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1M10
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Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain
分子名称: Glycoprotein Ib alpha, von Willebrand Factor
著者Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P.
登録日2002-06-16
公開日2002-08-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
1M0Z
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Crystal Structure of the von Willebrand Factor Binding Domain of Glycoprotein Ib alpha
分子名称: Glycoprotein Ib alpha
著者Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P.
登録日2002-06-16
公開日2002-08-28
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
1GWB
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STRUCTURE OF GLYCOPROTEIN 1B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ...
著者Emsley, J, Uff, S, Clemetson, K.J.M, Clemetson, J.M, Harrison, T.
登録日2002-03-14
公開日2003-02-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals an Unmasking Mechanism of Receptor Activation
J.Biol.Chem., 277, 2002
1P8V
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CRYSTAL STRUCTURE OF THE COMPLEX OF PLATELET RECEPTOR GPIB-ALPHA AND ALPHA-THROMBIN AT 2.6A
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIISOPROPYL PHOSPHONATE, ...
著者Dumas, J.J, Kumar, R, Seehra, J, Somers, W.S, Mosyak, L.
登録日2003-05-07
公開日2003-07-22
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the GpIbalpha-Thrombin Complex Essential for Platelet Aggregation
Science, 301, 2003
1P9A
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Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain precursor, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Varughese, K.I, Celikel, R, Ruggeri, Z.M.
登録日2003-05-09
公開日2003-07-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
1OOK
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Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Human Alpha Thrombin, ...
著者Varughese, K.I, Celikel, R, Ruggeri, Z.M.
登録日2003-03-03
公開日2003-07-22
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
Science, 301, 2003
1QYY
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Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PLATINUM (II) ION, Platelet glycoprotein Ib alpha chain, ...
著者Varughese, K.I, Ruggeri, Z.M, Celikel, R.
登録日2003-09-12
公開日2004-03-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain.
Acta Crystallogr.,Sect.D, 60, 2004
1SQ0
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Crystal Structure of the Complex of the Wild-type Von Willebrand Factor A1 domain and Glycoprotein Ib alpha at 2.6 Angstrom Resolution
分子名称: Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin], Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II]
著者Dumas, J.J, Kumar, R, McDonagh, T, Sullivan, F, Stahl, M.L, Somers, W.S, Mosyak, L.
登録日2004-03-17
公開日2004-04-13
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
1W8A
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Third LRR domain of Drosophila Slit
分子名称: SLIT PROTEIN
著者Howitt, J.A, Clout, N.J, Hohenester, E.
登録日2004-09-17
公開日2004-10-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Binding Site for Robo Receptors Revealed by Dissection of the Leucine-Rich Repeat Region of Slit.
Embo J., 23, 2004
1XCD
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Dimeric bovine tissue-extracted decorin, crystal form 1
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin
著者Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J.
登録日2004-09-01
公開日2004-11-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
1XEC
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Dimeric bovine tissue-extracted decorin, crystal form 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin
著者Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J.
登録日2004-09-09
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.USA, 101, 2004
1XKU
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Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Decorin
著者Scott, P.G, McEwan, P.A, Dodd, C.M, Bergmann, E.M, Bishop, P.N, Bella, J.
登録日2004-09-29
公開日2004-11-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan
Proc.Natl.Acad.Sci.Usa, 101, 2004
1XWD
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Crystal Structure of Human Follicle Stimulating Hormone Complexed with its Receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle stimulating hormone receptor, ...
著者Fan, Q.R, Hendrickson, W.A.
登録日2004-10-30
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structure of human follicle-stimulating hormone in complex with its receptor.
Nature, 433, 2005
1U0N
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The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex
分子名称: Botrocetin, Platelet glycoprotein Ib, Von Willebrand factor
著者Fukuda, K, Liddington, R.C.
登録日2004-07-13
公開日2005-04-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
2FT3
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Crystal structure of the biglycan dimer core protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Biglycan, CITRATE ANION
著者Scott, P.G, Dodd, C.M, Bergmann, E.M.
登録日2006-01-23
公開日2006-03-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structure of the Biglycan Dimer and Evidence That Dimerization Is Essential for Folding and Stability of Class I Small Leucine-rich Repeat Proteoglycans.
J.Biol.Chem., 281, 2006
2O6R
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Structural diversity of the hagfish Variable Lymphocyte Receptors B61
分子名称: Variable lymphocyte receptor B
著者Lee, J.O, Kim, H.M, Oh, S.C.
登録日2006-12-08
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural diversity of the hagfish variable lymphocyte receptors
J.Biol.Chem., 282, 2007
2Z66
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Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
著者Lee, J.-O, Kim, H.M, Park, B.S.
登録日2007-07-22
公開日2007-09-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
2V9T
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Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
分子名称: ROUNDABOUT HOMOLOG 1, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-08-25
公開日2007-09-25
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9S
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Second LRR domain of human Slit2
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-08-25
公開日2007-09-25
最終更新日2014-11-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2WFH
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The Human Slit 2 Dimerization Domain D4
分子名称: SLIT HOMOLOG 2 PROTEIN C-PRODUCT, SULFATE ION
著者Seiradake, E, von Philipsborn, A.C, Henry, M, Fritz, M, Lortat-Jacob, H, Jamin, M, Hemrika, W, Bastmeyer, M, Cusack, S, McCarthy, A.A.
登録日2009-04-06
公開日2009-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and functional relevance of the Slit2 homodimerization domain.
EMBO Rep., 10, 2009
3G39
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Structure of a lamprey variable lymphocyte receptor
分子名称: Variable lymphocyte receptor VLRB.2D
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2009-02-02
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3A
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Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen
分子名称: Lysozyme C, Variable lymphocyte receptor VLRB.2D
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2009-02-02
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3B
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Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen
分子名称: Lysozyme C, variable lymphocyte receptor VLRB.2D
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2009-02-02
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3P72
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structure of platelet Glycoprotein 1b alpha with a bound peptide inhibitor
分子名称: CHLORIDE ION, OS1 peptide, Platelet glycoprotein Ib alpha chain
著者McEwan, P.A, Andrews, R.K, Emsley, J.
登録日2010-10-12
公開日2010-11-24
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism.
Blood, 114, 2009
3PMH
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Mechanism of Sulfotyrosine-Mediated Glycoprotein Ib Interaction with Two Distinct alpha-Thrombin Sites
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide, Platelet glycoprotein Ib alpha chain, ...
著者Varughese, K.I, Celikel, R.
登録日2010-11-16
公開日2011-06-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Proc.Natl.Acad.Sci.USA, 108, 2011

 

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