4LG7
 
 | | Crystal structure MBD4 MBD domain in complex with methylated CpG DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 4, UNKNOWN ATOM OR ION | | 著者 | Xu, C, Tempel, W, Wernimont, A.K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-27 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure MBD4 MBD domain in complex with methylated CpG DNA
To be Published
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1UB1
 | | Solution structure of the matrix attachment region-binding domain of chicken MeCP2 | | 分子名称: | attachment region binding protein | | 著者 | Heitmann, B, Maurer, T, Weitzel, J.M, Stratling, W.H, Kalbitzer, H.R, Brunner, E, Structural Proteomics in Europe (SPINE) | | 登録日 | 2003-03-27 | | 公開日 | 2003-08-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the matrix attachment region-binding domain of chicken MeCP2
EUR.J.BIOCHEM., 270, 2003
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1IG4
 | | Solution Structure of the Methyl-CpG-Binding Domain of Human MBD1 in Complex with Methylated DNA | | 分子名称: | 5'-D(*GP*TP*AP*TP*CP*(5CM)P*GP*GP*AP*TP*AP*C)-3', Methyl-CpG Binding Protein | | 著者 | Ohki, I, Shimotake, N, Fujita, N, Jee, J.-G, Ikegami, T, Nakao, M, Shirakawa, M. | | 登録日 | 2001-04-17 | | 公開日 | 2001-05-30 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.
Cell(Cambridge,Mass.), 105, 2001
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1D9N
 | | SOLUTION STRUCTURE OF THE METHYL-CPG-BINDING DOMAIN OF THE METHYLATION-DEPENDENT TRANSCRIPTIONAL REPRESSOR MBD1/PCM1 | | 分子名称: | METHYL-CPG-BINDING PROTEIN MBD1 | | 著者 | Ohki, I, Shimotake, N, Fujita, N, Nakao, M, Shirakawa, M. | | 登録日 | 1999-10-28 | | 公開日 | 2000-10-28 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1.
EMBO J., 18, 1999
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3C2I
 | | The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF | | 分子名称: | DNA (5'-D(*DAP*DTP*DAP*DGP*DAP*DAP*DGP*DAP*DAP*DTP*DTP*DCP*(5CM)P*DGP*DTP*DTP*DCP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DCP*DTP*DGP*DGP*DAP*DAP*(5CM)P*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DTP*DA)-3'), Methyl-CpG-binding protein 2 | | 著者 | Ho, K.L, McNae, I.W, Schmiedeberg, L, Klose, R.J, Bird, A.P, Walkinshaw, M.D. | | 登録日 | 2008-01-25 | | 公開日 | 2008-05-13 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | MeCP2 binding to DNA depends upon hydration at methyl-CpG
Mol.Cell, 29, 2008
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7WIN
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6YWW
 | | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion | | 分子名称: | DNA (5'-D(*AP*TP*AP*TP*AP*AP*TP*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*CP*AP*G)-3'), DNA/RNA (5'-D(*TP*CP*TP*GP*CP*AP*CP*A)-R(P*(5HC))-D(P*AP*CP*AP*CP*AP*AP*TP*TP*AP*TP*A)-3'), Truncated methyl CpG binding protein 2 transcript 1 | | 著者 | Ibrahim, A, Papin, C, Mohideen-Abdul, K, Gras, S.L, Stoll, I, Bronner, C, Dimitrov, S, Klaholz, B.P, Hamiche, A. | | 登録日 | 2020-04-30 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion.
Science, 372, 2021
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1QK9
 | | The solution structure of the domain from MeCP2 that binds to methylated DNA | | 分子名称: | METHYL-CPG-BINDING PROTEIN 2 | | 著者 | Wakefield, R.I.D, Smith, B.O, Nan, X, Free, A, Soteriou, A, Uhrin, D, Bird, A.P, Barlow, P.N. | | 登録日 | 1999-07-12 | | 公開日 | 1999-10-08 | | 最終更新日 | 2018-04-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structure of the Domain from Mecp2 that Binds to Methylated DNA
J.Mol.Biol., 291, 1999
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7RAY
 | | Crystal structure of MBD2 with DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*A)-R(P*(5MC))-D(P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION | | 著者 | Liu, K, Dong, A, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2021-07-05 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of MBD2 with DNA
To Be Published
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8AJR
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8ALQ
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6OGJ
 | | MeCP2 MBD in complex with DNA | | 分子名称: | DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*CP*AP*CP*TP*CP*CP*G)-3'), Methyl-CpG-binding protein 2, ... | | 著者 | Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2019-04-02 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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6OGK
 | | MeCP2 MBD in complex with DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*CP*TP*CP*CP*G)-3'), ... | | 著者 | Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | | 登録日 | 2019-04-02 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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5AGQ
 | | Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes | | 分子名称: | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A | | 著者 | Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M. | | 登録日 | 2015-02-03 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
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5BT2
 | | MeCP2 MBD domain (A140V) in complex with methylated DNA | | 分子名称: | DNA (5'-D(*AP*TP*AP*GP*AP*AP*GP*AP*AP*TP*TP*CP*(5CM)P*GP*TP*TP*CP*CP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*GP*GP*AP*AP*(5CM)P*GP*GP*AP*AP*TP*TP*CP*TP*TP*CP*TP*A)-3'), Methyl-CpG-binding protein 2 | | 著者 | Ho, K.L, Chia, J.Y, Tan, W.S, Ng, C.L, Hu, N.J, Foo, H.L. | | 登録日 | 2015-06-02 | | 公開日 | 2016-08-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence.
Sci Rep, 6, 2016
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7FEO
 | | Crystal structure of AtMBD5 MBD domain | | 分子名称: | Methyl-CpG-binding domain-containing protein 5, SULFATE ION | | 著者 | Zhou, M.Q, Wu, Z.B, Liu, K, Min, J.R, Structural Genomics Consortium (SGC) | | 登録日 | 2021-07-21 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs.
J.Mol.Biol., 434, 2022
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7FEF
 | | Crystal structure of AtMBD6 with DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain-containing protein 6 | | 著者 | Wu, Z.B, Liu, K, Min, J.R. | | 登録日 | 2021-07-19 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs.
J.Mol.Biol., 434, 2022
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7FHJ
 | | Crystal structure of BAZ2A with DNA | | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | | 著者 | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | | 登録日 | 2021-07-29 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.
J.Biol.Chem., 297, 2021
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2KY8
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2MOE
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2MB7
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3VXV
 | | Crystal structure of methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*CP*(5CM)P*GP*GP*AP*CP*A)-3'), ... | | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2012-09-21 | | 公開日 | 2013-01-16 | | 最終更新日 | 2013-08-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
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7D8K
 | | Solution structure of the methyl-CpG binding domain of MBD6 from Arabidopsis thaliana | | 分子名称: | Methyl-CpG-binding domain-containing protein 6 | | 著者 | Mahana, Y, Ohki, I, Walinda, E, Morimoto, D, Sugase, K, Shirakawa, M. | | 登録日 | 2020-10-08 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insights into Methylated DNA Recognition by the Methyl-CpG Binding Domain of MBD6 from Arabidopsis thaliana .
Acs Omega, 7, 2022
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3VYB
 | | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/hmCG sequence | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5HC)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2012-09-22 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
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3VXX
 | | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5CM)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2012-09-21 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
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