8EMT
| Cryo-EM analysis of the human aldehyde oxidase from liver | 分子名称: | Aldehyde oxidase, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Su, C, Lyu, M, Zhang, Z, Yu, E.W. | 登録日 | 2022-09-28 | 公開日 | 2023-05-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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1DGJ
| CRYSTAL STRUCTURE OF THE ALDEHYDE OXIDOREDUCTASE FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 | 分子名称: | ALDEHYDE OXIDOREDUCTASE, FE2/S2 (INORGANIC) CLUSTER, MOLYBDENUM (IV)OXIDE, ... | 著者 | Rebelo, J.M, Macieira, S, Dias, J.M, Huber, R, Romao, M.J. | 登録日 | 1999-11-24 | 公開日 | 2000-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Gene sequence and crystal structure of the aldehyde oxidoreductase from Desulfovibrio desulfuricans ATCC 27774. J.Mol.Biol., 297, 2000
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8J79
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7PX0
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6Q6Q
| Human aldehyde oxidase SNP G1269R | 分子名称: | Aldehyde oxidase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Mota, C, Coelho, C, Santos-Silva, T, Romao, M.J. | 登録日 | 2018-12-11 | 公開日 | 2019-05-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.10003781 Å) | 主引用文献 | Human aldehyde oxidase (hAOX1): structure determination of the Moco-free form of the natural variant G1269R and biophysical studies of single nucleotide polymorphisms. Febs Open Bio, 9, 2019
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7DQX
| Crystal structure of xanthine dehydrogenase family protein | 分子名称: | 6-hydroxypseudooxynicotine dehydrogenase complex subunit alpha, 6-hydroxypseudooxynicotine dehydrogenase complex subunit beta, 6-hydroxypseudooxynicotine dehydrogenase complex subunit gamma, ... | 著者 | Lei, W. | 登録日 | 2020-12-24 | 公開日 | 2022-01-26 | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | 主引用文献 | crystal structure of xanthine dehydrogenase family protein To Be Published
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5Y6Q
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2W3S
| Crystal Structure of Xanthine Dehydrogenase (desulfo form) from Rhodobacter capsulatus in Complex with Xanthine | 分子名称: | CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Dietzel, U, Kuper, J, Leimkuhler, S, Kisker, C. | 登録日 | 2008-11-14 | 公開日 | 2008-12-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Mechanism of Substrate and Inhibitor Binding of Rhodobacter Capsulatus Xanthine Dehydrogenase. J.Biol.Chem., 284, 2009
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3HRD
| Crystal structure of nicotinate dehydrogenase | 分子名称: | CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wagener, N, Pierik, A.J, Hille, R, Dobbek, H. | 登録日 | 2009-06-09 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Mo-Se active site of nicotinate dehydrogenase Proc.Natl.Acad.Sci.USA, 106, 2009
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4UHW
| Human aldehyde oxidase | 分子名称: | ALDEHYDE OXIDASE, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Coelho, C, Romao, M.J, Santos-Silva, T. | 登録日 | 2015-03-26 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Insights Into Xenobiotic and Inhibitor Binding to Human Aldehyde Oxidase Nat.Chem.Biol., 11, 2015
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4UHX
| Human aldehyde oxidase in complex with phthalazine and thioridazine | 分子名称: | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, 10-{2-[(2S)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, ALDEHYDE OXIDASE, ... | 著者 | Coelho, C, Romao, M.J, Santos-Silva, T. | 登録日 | 2015-03-26 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Insights Into Xenobiotic and Inhibitor Binding to Human Aldehyde Oxidase Nat.Chem.Biol., 11, 2015
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7ORC
| Human Aldehyde Oxidase in complex with Raloxifene | 分子名称: | Aldehyde oxidase, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Mota, C, Coelho, C, Santos Silva, T, Romao, M.J. | 登録日 | 2021-06-05 | 公開日 | 2021-09-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case. J.Med.Chem., 64, 2021
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7OPN
| Human Aldehyde Oxidase SNP R1231H in complex with Raloxifene | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Aldehyde oxidase, DIMETHYL SULFOXIDE, ... | 著者 | Mota, C, Coelho, C, Santos Silva, T, Romao, M.J. | 登録日 | 2021-06-01 | 公開日 | 2021-09-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case. J.Med.Chem., 64, 2021
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3L4P
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4US9
| Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with 3- phenylpropionaldehyde | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), 3-PHENYLPROPANAL, ALDEHYDE OXIDOREDUCTASE, ... | 著者 | Correia, H.D, Romao, M.J, Santos-Silva, T. | 登録日 | 2014-07-03 | 公開日 | 2014-10-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
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4USA
| Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with trans-cinnamaldehyde | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | 著者 | Correia, H.D, Romao, M.J, Santos-Silva, T. | 登録日 | 2014-07-03 | 公開日 | 2014-10-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
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4US8
| Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with benzaldehyde | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | 著者 | Correia, H.D, Romao, M.J, Santos-Silva, T. | 登録日 | 2014-07-03 | 公開日 | 2014-10-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
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5EPG
| Human aldehyde oxidase SNP S1271L | 分子名称: | Aldehyde oxidase, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Coelho, C, Romao, M.J, Santos-Silva, T. | 登録日 | 2015-11-11 | 公開日 | 2016-02-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms. Drug Metab.Dispos., 44, 2016
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4C7Z
| Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), activated with sodium dithionite and sodium sulfide | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | 著者 | Correia, H.D, Romao, M.J, Santos-Silva, T. | 登録日 | 2013-09-27 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Kinetic and Structural Studies of Aldehyde Oxidoreductase from Desulfovibrio Gigas Reveal a Dithiolene-Based Chemistry for Enzyme Activation and Inhibition by H2O2. Plos One, 8, 2013
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4C7Y
| Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with sodium dithionite and sodium sulfide | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | 著者 | Correia, H.D, Romao, M.J, Santos-Silva, T. | 登録日 | 2013-09-27 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Kinetic and Structural Studies of Aldehyde Oxidoreductase from Desulfovibrio Gigas Reveal a Dithiolene-Based Chemistry for Enzyme Activation and Inhibition by H2O2. Plos One, 8, 2013
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4C80
| Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with hydrogen peroxide | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | 著者 | Correia, H.D, Romao, M.J, Santos-Silva, T. | 登録日 | 2013-09-27 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Kinetic and Structural Studies of Aldehyde Oxidoreductase from Desulfovibrio Gigas Reveal a Dithiolene-Based Chemistry for Enzyme Activation and Inhibition by H2O2. Plos One, 8, 2013
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2CKJ
| Human milk xanthine oxidoreductase | 分子名称: | ACETIC ACID, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Pearson, A.R, Godber, B.L.J, Eisenthal, R, Taylor, G.L, Harrison, R. | 登録日 | 2006-04-19 | 公開日 | 2007-05-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Human Milk Xanthine Dehydrogenase is Incompletely Converted to the Oxidase Form in the Absence of Proteolysis. A Structural Explanation. To be Published
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5G5H
| Escherichia coli Periplasmic Aldehyde Oxidase R440H mutant | 分子名称: | ACETATE ION, Aldehyde oxidoreductase FAD-binding subunit PaoB, Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA, ... | 著者 | Correia, M.A.S, Otrelo-Cardoso, A.R, Romao, M.J, Santos-Silva, T. | 登録日 | 2016-05-25 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Escherichia Coli Periplasmic Aldehyde Oxidoreductase is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes. Acs Chem.Biol., 11, 2016
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5G5G
| Escherichia coli Periplasmic Aldehyde Oxidase | 分子名称: | ACETATE ION, CHLORIDE ION, DIOXOTHIOMOLYBDENUM(VI) ION, ... | 著者 | Correia, M.A.S, Otrelo-Cardoso, A.R, Romao, M.J, Santos-Silva, T. | 登録日 | 2016-05-25 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Escherichia Coli Periplasmic Aldehyde Oxidoreductase is an Exceptional Member of the Xanthine Oxidase Family of Molybdoenzymes. Acs Chem.Biol., 11, 2016
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2E1Q
| Crystal Structure of Human Xanthine Oxidoreductase mutant, Glu803Val | 分子名称: | 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ... | 著者 | Yamaguchi, Y, Matsumura, T, Ichida, K, Okamoto, K, Nishino, T. | 登録日 | 2006-10-27 | 公開日 | 2007-09-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate J.Biochem.(Tokyo), 141, 2007
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