1PRY
 
 | | Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527) | | 分子名称: | Fibrillarin-like pre-rRNA processing protein | | 著者 | Deng, L, Starostina, N.G, Liu, Z.-J, Rose, J.P, Terns, R.M, Terns, M.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2003-06-20 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus
Biochem.Biophys.Res.Commun., 315, 2004
|
|
2IPX
 | | Human Fibrillarin | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CALCIUM ION, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2006-10-12 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The Crystal Structure of Human Fibrillarin in complex with SAH
To be Published
|
|
4DF3
 | |
1FBN
 | | CRYSTAL STRUCTURE OF A FIBRILLARIN HOMOLOGUE FROM METHANOCOCCUS JANNASCHII, A HYPERTHERMOPHILE, AT 1.6 A | | 分子名称: | MJ FIBRILLARIN HOMOLOGUE | | 著者 | Wang, H, Boisvert, D, Kim, K.K, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 1999-04-25 | | 公開日 | 2000-04-26 | | 最終更新日 | 2014-11-26 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.
EMBO J., 19, 2000
|
|
1G8S
 | |
1G8A
 | |
7SEB
 | | Crystal structure of human Fibrillarin in complex with compound 2 from single soak | | 分子名称: | 6-(trifluoromethyl)pyrimidin-4-amine, FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SEC
 | | Crystal structure of human Fibrillarin in complex with compound 1a | | 分子名称: | 2-[(8S)-4-oxo-2-(trifluoromethyl)-4,5-dihydropyrazolo[1,5-a]pyrazin-6-yl]acetamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SED
 | | Crystal structure of human Fibrillarin in complex with compound 2a | | 分子名称: | FORMIC ACID, N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SE6
 | | Crystal structure of human Fibrillarin in ligand-free state | | 分子名称: | FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SE7
 | | Crystal structure of human Fibrillarin in complex with S-adenosyl-L-methionine | | 分子名称: | S-ADENOSYLMETHIONINE, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SE9
 | | Crystal structure of human Fibrillarin in complex with compound 1 from single soak | | 分子名称: | (5S)-3-methyl-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazin-1(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SEA
 | | Crystal structure of human Fibrillarin in complex with compound 2 from cocktail soak | | 分子名称: | 6-(trifluoromethyl)pyrimidin-4-amine, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
7SE8
 | | Crystal structure of human Fibrillarin in complex with fragment 1 from cocktail soak | | 分子名称: | (5S)-3-methyl-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazin-1(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... | | 著者 | Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T. | | 登録日 | 2021-09-30 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
|
|
2NNW
 | | Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs | | 分子名称: | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein | | 著者 | Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H. | | 登録日 | 2006-10-24 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.
J.Mol.Biol., 371, 2007
|
|
7XPL
 | |
1NT2
 | | CRYSTAL STRUCTURE OF FIBRILLARIN/NOP5P COMPLEX | | 分子名称: | Fibrillarin-like pre-rRNA processing protein, S-ADENOSYLMETHIONINE, conserved hypothetical protein | | 著者 | Aittaleb, M, Rashid, R, Chen, Q, Palmer, J.R, Daniels, C.J, Li, H. | | 登録日 | 2003-01-28 | | 公開日 | 2003-04-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure and function of archaeal box C/D sRNP core proteins.
Nat.Struct.Biol., 10, 2003
|
|
3ID6
 | |
3NVM
 | |
6ZDT
 | | Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain | | 分子名称: | Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin | | 著者 | Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W. | | 登録日 | 2020-06-15 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Rna, 27, 2021
|
|
5OQL
 | | Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum | | 分子名称: | 35S rRNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ... | | 著者 | Cheng, J, Kellner, N, Berninghausen, O, Hurt, E, Beckmann, R. | | 登録日 | 2017-08-12 | | 公開日 | 2017-10-11 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017
|
|
6ND4
 | | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | | 分子名称: | 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ... | | 著者 | Hunziker, M, Barandun, J, Klinge, S. | | 登録日 | 2018-12-13 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit.
Elife, 8, 2019
|
|
5JPQ
 | | Cryo-EM structure of the 90S pre-ribosome | | 分子名称: | 18S ribosomal RNA, Bms1, Emg1, ... | | 著者 | Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R. | | 登録日 | 2016-05-04 | | 公開日 | 2016-07-27 | | 最終更新日 | 2020-03-11 | | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | | 主引用文献 | Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome.
Cell, 166, 2016
|
|
4BY9
 | | The structure of the Box CD enzyme reveals regulation of rRNA methylation | | 分子名称: | 5'-R(*UP*CP*GP*CP*CP*CP*AP*UP*CP*AP*CP)-3', 50S RIBOSOMAL PROTEIN L7AE, FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERASE, ... | | 著者 | Lapinaite, A, Simon, B, Skjaerven, L, Rakwalska-Bange, M, Gabel, F, Carlomagno, T. | | 登録日 | 2013-07-18 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
Nature, 502, 2013
|
|
3ID5
 | |
