3SPW
 
 | | Structure of Osh4p/Kes1p in complex with phosphatidylinositol 4-phosphate | | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Protein KES1 | | 著者 | Delfosse, V, de Saint-Jean, M, Douguet, D, Antonny, B, Drin, G, Bourguet, W. | | 登録日 | 2011-07-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers.
J.Cell Biol., 195, 2011
|
|
5H2D
 | | Crystal structure of Osh1 ORD domain in complex with ergosterol | | 分子名称: | ERGOSTEROL, KLLA0C04147p, SULFATE ION | | 著者 | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | | 登録日 | 2016-10-14 | | 公開日 | 2017-05-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
|
|
5WVR
 | | Crystal structure of Osh1 ORD domain in complex with cholesterol | | 分子名称: | CHOLESTEROL, KLLA0C04147p, SULFATE ION | | 著者 | Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. | | 登録日 | 2016-12-28 | | 公開日 | 2017-05-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
|
|
8P7A
 | |
7V62
 | | Crystal structure of human OSBP ORD in complex with cholesterol | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHOLESTEROL, CITRIC ACID, ... | | 著者 | Kobayashi, J, Kato, R. | | 登録日 | 2021-08-19 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Ligand Recognition by the Lipid Transfer Domain of Human OSBP Is Important for Enterovirus Replication.
Acs Infect Dis., 8, 2022
|
|
4PH7
 | | Structure of Osh6p in complex with phosphatidylinositol 4-phosphate | | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, Oxysterol-binding protein homolog 6 | | 著者 | Delfosse, V, Moser von Filseck, J, Antonny, B, Bourguet, W, Drin, G. | | 登録日 | 2014-05-05 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate.
Science, 349, 2015
|
|
4B2Z
 | | Structure of Osh6 in complex with phosphatidylserine | | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... | | 著者 | Maeda, K, Anand, K, Chiapparino, A, Kumar, A, Poletto, M, Kaksonen, M, Gavin, A.C. | | 登録日 | 2012-07-19 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Interactome Map Uncovers Phosphatidylserine Transport by Oxysterol-Binding Proteins
Nature, 501, 2013
|
|
7CYZ
 | | The structure of human ORP3 OSBP-related domain | | 分子名称: | Oxysterol-binding protein-related protein 3 | | 著者 | Dong, X. | | 登録日 | 2020-09-05 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of ORP3 reveals the conservative PI4P binding pattern.
Biochem.Biophys.Res.Commun., 529, 2020
|
|
4INQ
 | | Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae | | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein homolog 3 | | 著者 | Tong, J, Im, Y.J. | | 登録日 | 2013-01-05 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
|
|
7DEJ
 | | Structure of human ORP3 ORD in apo-form | | 分子名称: | Oxysterol-binding protein-related protein 3 | | 著者 | Tong, J, Tan, L, Im, Y.J. | | 登録日 | 2020-11-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Plos One, 16, 2021
|
|
7DEI
 | | Structure of human ORP3 ORD domain in complex with PI(4)P | | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein-related protein 3 | | 著者 | Tong, J, Tan, L, Im, Y.J. | | 登録日 | 2020-11-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Plos One, 16, 2021
|
|
4IC4
 | |
4JCH
 | | OSH4 bound to an electrophilic oxysterol | | 分子名称: | (3beta,9beta,22R,25R)-3-hydroxyfurost-5-en-27-yl propanoate, Protein KES1 | | 著者 | Koag, M.C, Kou, Y.I, Monzingo, A.F, Lee, S. | | 登録日 | 2013-02-21 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of OSH4 bound to an electrophilic oxysterol
To be Published
|
|
4F4B
 | | Structure of OSH4 with a cholesterol analog | | 分子名称: | (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione, Protein KES1 | | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | | 登録日 | 2012-05-10 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
|
|
4FES
 | | Structure of OSH4 in complex with cholesterol analogs | | 分子名称: | (3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2S,6S)-6-methyl-3-oxooctan-2-yl]-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-16H-cyclopenta[a]phenanthren-16-one, Protein KES1 | | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | | 登録日 | 2012-05-30 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
|
|
5ZM7
 | | Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | 著者 | Dong, J, Wang, J, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
|
|
5ZM6
 | | Crystal structure of ORP1-ORD in complex with PI(4,5)P2 | | 分子名称: | ACETATE ION, Oxysterol-binding protein-related protein 1, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | | 著者 | Dong, J, Wang, J, Luo, Z, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
|
|
5ZM5
 | | Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution | | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | 著者 | Dong, J, Wang, J, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
|
|
5ZM8
 | | Crystal structure of ORP2-ORD in complex with PI(4,5)P2 | | 分子名称: | Oxysterol-binding protein-related protein 2, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | | 著者 | Wang, H, Dong, J.Q, Wang, J, Wu, J.W. | | 登録日 | 2018-04-01 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).
Mol. Cell, 73, 2019
|
|
1ZHW
 | | Structure of yeast oxysterol binding protein Osh4 in complex with 20-hydroxycholesterol | | 分子名称: | 20-HYDROXYCHOLESTEROL, KES1 protein, LEAD (II) ION | | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | | 登録日 | 2005-04-26 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
|
|
1ZI7
 | | Structure of truncated yeast oxysterol binding protein Osh4 | | 分子名称: | KES1 protein, SULFATE ION | | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | | 登録日 | 2005-04-27 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
|
|
1ZHX
 | | Structure of yeast oxysterol binding protein Osh4 in complex with 25-hydroxycholesterol | | 分子名称: | 25-HYDROXYCHOLESTEROL, KES1 protein | | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | | 登録日 | 2005-04-26 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
|
|
1ZHZ
 | | Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol | | 分子名称: | ERGOSTEROL, KES1 protein, LEAD (II) ION | | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | | 登録日 | 2005-04-26 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
|
|
1ZHY
 | | Structure of yeast oxysterol binding protein Osh4 in complex with cholesterol | | 分子名称: | CHOLESTEROL, KES1 protein, LEAD (II) ION | | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | | 登録日 | 2005-04-26 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
|
|
1ZHT
 | | Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol | | 分子名称: | 7-HYDROXYCHOLESTEROL, KES1 protein | | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | | 登録日 | 2005-04-26 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins
Nature, 437, 2005
|
|
