PDB: 12 件ウェブページステータス検索Chemie searchBIRD

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1CSG	Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor 分子名称: Granulocyte-macrophage colony-stimulating factor 著者 Walter, M.R, Cook, W.J, Ealick, S.E. 登録日 1992-11-23 公開日 1993-10-31 最終更新日 2016-01-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor. J.Mol.Biol., 224, 1992
2GMF	HUMAN GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR 分子名称: GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR 著者 Rozwarski, D, Diederichs, K, Hecht, R, Boone, T, Karplus, P.A. 登録日 1996-04-24 公開日 1996-11-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor. Proteins, 26, 1996
5D70	Crystal structure of MOR03929, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF 分子名称: Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, heavy chain, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-08-13 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
5D72	Crystal structure of MOR04252, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF 分子名称: DI(HYDROXYETHYL)ETHER, Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-08-13 公開日 2015-10-14 最終更新日 2016-01-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
6BFQ	The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies 分子名称: Fab Heavy chain, Fab Light Chain, Granulocyte-macrophage colony-stimulating factor 著者 Dhagat, U, Hercus, T.R, Broughton, S.E, Nero, T.L, Lopez, A.F, Parker, M.W. 登録日 2017-10-26 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. MAbs, 10, 2018
6BFS	The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies 分子名称: Fab Heavy Chain, Fab light Chain, Granulocyte-macrophage colony-stimulating factor 著者 Dhagat, U, Hercus, T.R, Broughton, S.E, Nero, T.L, Lopez, A.F, Parker, M.W. 登録日 2017-10-26 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. MAbs, 10, 2018
5C7X	Crystal structure of MOR04357, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, DI(HYDROXYETHYL)ETHER, Granulocyte-macrophage colony-stimulating factor, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-06-25 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
5D28	Complex of GM-CSF/IL-2 inhibition factor with Granulocyte-macrophage colony-stimulating factor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GM-CSF/IL-2 inhibition factor, ... 著者 Felix, J, Savvides, S.N. 登録日 2015-08-05 公開日 2016-11-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.845 Å) 主引用文献 Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF. Nat Commun, 7, 2016
5D71	Crystal structure of MOR04302, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF 分子名称: DI(HYDROXYETHYL)ETHER, Granulocyte-macrophage colony-stimulating factor, Immunglobulin G1 Fab fragment, ... 著者 Eylenstein, R, Weinfurtner, D, Steidl, S, Boettcher, J, Augustin, M. 登録日 2015-08-13 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. Mabs, 8, 2016
5D22	Structure of ovine granulocyte-macrophage colony-stimulating factor 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Granulocyte-macrophage colony-stimulating factor 著者 Felix, J, Savvides, S.N. 登録日 2015-08-05 公開日 2016-11-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.994 Å) 主引用文献 Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF. Nat Commun, 7, 2016
4RS1	Crystal structure of receptor-cytokine complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Granulocyte-macrophage colony-stimulating factor, ... 著者 Broughton, S.E, Parker, M.W, Dhagat, U. 登録日 2014-11-06 公開日 2015-11-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24, 2016
4NKQ	Structure of a Cytokine Receptor Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Granulocyte-macrophage colony-stimulating factor, ... 著者 Parker, M.W, Broughton, S.E. 登録日 2013-11-13 公開日 2015-09-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24, 2016