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2PR9
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Mu2 adaptin subunit (AP50) of AP2 adaptor (second domain), complexed with GABAA receptor-gamma2 subunit-derived internalization peptide DEEYGYECL
分子名称: AP-2 complex subunit mu-1, GABA(A) receptor subunit gamma-2 peptide
著者Vahedi-Faridi, A, Haucke, V, Kittler, J.T, Kukhtina, V, Moss, S.J, Saenger, W, Chen, G.-J, Tretter, V, Smith, K, Yan, Z, McAinsh, K, Arancibia-Carcamo, L.
登録日2007-05-04
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor gamma2 subunit.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1BXX
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH TGN38 INTERNALIZATION PEPTIDE DYQRLN
分子名称: PROTEIN (AP50), PROTEIN (TGN38 PEPTIDE)
著者Owen, D.J, Evans, P.R.
登録日1998-10-08
公開日1998-11-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A structural explanation for the recognition of tyrosine-based endocytotic signals.
Science, 282, 1998
1BW8
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM
分子名称: PROTEIN (INTERNALIZATION SIGNAL FROM EGFR), PROTEIN (MU2 ADAPTIN SUBUNIT)
著者Owen, D.J, Evans, P.R.
登録日1998-09-30
公開日1998-11-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A structural explanation for the recognition of tyrosine-based endocytotic signals.
Science, 282, 1998
3H85
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Molecular basis for the association of PIPKI gamma-p90 with the clathrin adaptor AP-2
分子名称: AP-2 complex subunit mu-1, NICKEL (II) ION, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
著者Vahedi-Faridi, A, Kahlfeldt, N, Schaefer, J.G, Haucke, V.
登録日2009-04-28
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
J.Biol.Chem., 285, 2010
4IKN
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Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38
分子名称: AP-3 complex subunit mu-1, Trans-Golgi network integral membrane protein TGN38
著者Mardones, G.A, Kloer, D.P, Burgos, P.V, Bonifacino, J.S, Hurley, J.H.
登録日2012-12-26
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structural basis for the recognition of tyrosine-based sorting signals by the mu 3A subunit of the AP-3 adaptor complex.
J.Biol.Chem., 288, 2013
3L81
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Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain, in complex with a sorting peptide from the amyloid precursor protein (APP)
分子名称: AP-4 complex subunit mu-1, Amyloid beta A4 protein, GLYCEROL
著者Mardones, G.A, Rojas, A.L, Burgos, P.V, Dasilva, L.L.P, Prabhu, Y, Bonifacino, J.S, Hurley, J.H.
登録日2009-12-29
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex.
Dev.Cell, 18, 2010
1HES
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH P-selectin INTERNALIZATION PEPTIDE SHLGTYGVFTNAA
分子名称: CLATHRIN COAT ASSEMBLY PROTEIN AP50, P-SELECTIN PEPTIDE
著者Owen, D.J, Evans, P.R, Green, S.A.
登録日2000-11-24
公開日2001-05-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Third Specificity-Determining Site in Mu 2 Adaptin for Sequences Upstream of Yxx Phi Sorting Motifs
Traffic, 2, 2001
1H6E
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH CTLA-4 INTERNALIZATION PEPTIDE TTGVYVKMPPT
分子名称: CLATHRIN COAT ASSEMBLY PROTEIN AP50, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4
著者Rowsell, S, Pauptit, R.A.
登録日2001-06-12
公開日2001-11-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Study of the Interaction of the Medium Chain Mu2 Subunit of the Clathrin-Associated Adapter Protein Complex 2 with Cytotoxic T-Lymphocyte Antigen 4 and Cd28
Biochem.J., 359, 2001
1I31
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM AT 2.5 A RESOLUTION
分子名称: CLATHRIN COAT ASSEMBLY PROTEIN AP50, EPIDERMAL GROWTH FACTOR RECEPTOR
著者Modis, Y, Boll, W, Rapoport, I, Kirchhausen, T.
登録日2001-02-12
公開日2001-02-21
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM AT 2.5 A RESOLUTION
To be Published
4MDR
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Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, in complex with a sorting peptide from the amyloid precursor protein (APP)
分子名称: AP-4 complex subunit mu-1, Amyloid beta A4 protein
著者Ross, B.H, Lin, Y, Corales, E.A, Burgos, P.V, Mardones, G.A.
登録日2013-08-23
公開日2014-03-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Characterization of Cargo-Binding Sites on the mu 4-Subunit of Adaptor Protein Complex 4.
Plos One, 9, 2014
4O8Q
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Crystal structure of bovine MHD domain of the COPI delta subunit at 2.15 A resolution
分子名称: Coatomer subunit delta, FORMIC ACID
著者Lahav, A, Rozenberg, H, Cassel, D, Adir, N.
登録日2013-12-29
公開日2015-01-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the bovine COPI delta subunit mu homology domain at 2.15 angstrom resolution.
Acta Crystallogr.,Sect.D, 71, 2015
5WRM
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Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1
著者Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S.
登録日2016-12-02
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
6BNT
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BU of 6bnt by Molmil
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1
著者Kikuchi, S, Choi, E, Yu, H.
登録日2017-11-17
公開日2018-11-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun, 10, 2019
5WRL
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Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1
著者Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S.
登録日2016-12-02
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.095 Å)
主引用文献IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
5WRK
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BU of 5wrk by Molmil
Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide
分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION
著者Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S.
登録日2016-12-02
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
5C7Z
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AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
分子名称: AP-2 complex subunit mu, Integrin alpha-4
著者Owen, D.J, Evans, P.R, Wilson, T.A.
登録日2015-06-25
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
5FJW
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Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWx(MSE) peptide
分子名称: COATOMER SUBUNIT DELTA, PROTEIN TRANSPORT PROTEIN DSL1
著者Suckling, R.J, Evans, P.R, Owen, D.J.
登録日2015-10-13
公開日2015-11-11
最終更新日2016-04-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FJZ
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Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWxV peptide
分子名称: COATOMER SUBUNIT DELTA, PROTEIN TRANSPORT PROTEIN DSL1
著者Suckling, R.J, Evans, P.R, Owen, D.J.
登録日2015-10-14
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FJX
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Yeast delta-COP-I mu-homology domain complexed with Gcs1 WxxF peptide
分子名称: ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN GCS1, COATOMER SUBUNIT DELTA
著者Suckling, R.J, Evans, P.R, Owen, D.J.
登録日2015-10-13
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
5FK0
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Yeast delta-COP-I mu-homology domain
分子名称: CALCIUM ION, COATOMER SUBUNIT DELTA
著者Suckling, R.J, Evans, P.R, Owen, D.J.
登録日2015-10-14
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Binding of Tryptophan-Based Motifs by Delta-Cop.
Proc.Natl.Acad.Sci.USA, 112, 2015
7OIT
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BU of 7oit by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form)
分子名称: AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL
著者Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
登録日2021-05-12
公開日2022-06-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OIQ
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Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form)
分子名称: AP-2 complex subunit mu, F-BAR domain only protein 2
著者Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
登録日2021-05-12
公開日2022-06-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OI5
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Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved)
分子名称: AP-2 complex subunit mu,F-BAR domain only protein 2, GLYCEROL
著者Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
登録日2021-05-11
公開日2022-06-01
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OFP
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Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor
分子名称: AP-2 complex subunit mu, CITRIC ACID, GLYCEROL
著者Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
登録日2021-05-05
公開日2022-06-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHZ
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Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged)
分子名称: AP-2 complex subunit mu,F-BAR domain only protein 2
著者Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
登録日2021-05-11
公開日2022-06-01
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022

 

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