PDB: 140 件ウェブページステータス検索Chemie searchBIRD

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6U8J	Crystal structure of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase/phospho-2-dehydro-3-deoxyheptonate aldolase (Aro3) from Candida auris 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, UNKNOWN ATOM OR ION 著者 Michalska, K, Evdokimova, E, Semper, C, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-09-05 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.492 Å) 主引用文献 Crystal structure of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase/phospho-2-dehydro-3-deoxyheptonate aldolase (Aro3) from Candida auris To Be Published
4LU0	Crystal structure of 2-Keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase from Pseudomonas aeruginosa. 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase 著者 Asojo, O.A. 登録日 2013-07-24 公開日 2013-10-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of 2-keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase from Pseudomonas aeruginosa. Acta Crystallogr.,Sect.F, 69, 2013
1D9E	STRUCTURE OF E. COLI KDO8P SYNTHASE 分子名称: 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE, SULFATE ION 著者 Radaev, S, Dastidar, P, Patel, M, Woodard, R.W, Gatti, D.L. 登録日 1999-10-27 公開日 2000-05-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and mechanism of 3-deoxy-D-manno-octulosonate 8-phosphate synthase. J.Biol.Chem., 275, 2000
7REU	Crystal structure of Aro4p, 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase from Candida auris, L-Tyr complex 分子名称: 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, CHLORIDE ION, GLYCEROL, ... 著者 Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-07-13 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal structure of Aro4p, 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase from Candida auris, L-Tyr complex To Be Published
7YKC	crystal structure of the Phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (ARO3) from Saccharomyces cerevisiae 分子名称: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase 著者 Liu, H, Luo, Y. 登録日 2022-07-22 公開日 2023-07-26 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Mechanistic investigation of a D to N mutation in DAHP synthase that dictates carbon flux into the shikimate pathway in yeast. Commun Chem, 6, 2023
6U57	KDO8PS Structure Determined at the EuXFEL using Segmented Flow Injection 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase 著者 Botha, S, Ros, A. 登録日 2019-08-27 公開日 2020-09-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Segmented flow generator for serial crystallography at the European X-ray free electron laser. Nat Commun, 11, 2020
6MDY	Crystal structure of a 2-dehydro-3-deoxyphosphooctonate aldolase from Legionella pneumophila Philadelphia 1 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-09-05 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of a 2-dehydro-3-deoxyphosphooctonate aldolase from Legionella pneumophila Philadelphia 1 To Be Published
7RUD	DAHP synthase complex with trifluoropyruvate oxime 分子名称: (2Z)-3,3,3-trifluoro-2-(hydroxyimino)propanoic acid, Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive 著者 Heimhalt, M, Mukherjee, P, Grainger, R, Szabla, R, Brown, C, Turner, R, Junop, M.S, Berti, P.J. 登録日 2021-08-16 公開日 2021-11-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition. Acs Infect Dis., 7, 2021
7RUE	DAHP synthase complexed with trifluoropyruvate semicarbazone 分子名称: (2E)-2-(2-carbamoylhydrazinylidene)-3,3,3-trifluoropropanoic acid, MANGANESE (II) ION, Phospho-2-dehydro-3-deoxyheptonate aldolase, ... 著者 Heimhalt, M, Mukherjee, P, Grainger, R, Szabla, R, Brown, C, Turner, R, Junop, M.S, Berti, P.J. 登録日 2021-08-16 公開日 2021-11-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition. Acs Infect Dis., 7, 2021
4C1K	Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOHEPTONATE ALDOLASE, CADMIUM ION, CARBONATE ION, ... 著者 Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. 登録日 2013-08-13 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Destabilization of the Homotetrameric Assembly of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from the Hyperthermophile Pyrococcus Furiosus Enhances Enzymatic Activity J.Mol.Biol., 426, 2014
4C1L	Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant 分子名称: 2-dehydro-3-deoxyphosphoheptonate aldolase, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. 登録日 2013-08-13 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity. J. Mol. Biol., 426, 2014
2A21	Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+ 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, PHOSPHOENOLPYRUVATE, ... 著者 Kona, F, Xu, X, Lu, J, Martin, P, Gatti, D.L. 登録日 2005-06-21 公開日 2006-06-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
2A2I	Aquifex aeolicus KDO8PS in complex with PEP, A5P, Zn2+ 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, ARABINOSE-5-PHOSPHATE, PHOSPHOENOLPYRUVATE, ... 著者 Kona, F, Xu, X, Lu, J, Martin, P, Gatti, D.L. 登録日 2005-06-22 公開日 2006-07-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
6AGL	Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive 著者 Cui, D, Qi, J, Wen, T. 登録日 2018-08-13 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli. J.Struct.Biol., 206, 2019
6AGM	Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive, TYROSINE 著者 Cui, D, Qi, J, Wen, T. 登録日 2018-08-13 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli. J.Struct.Biol., 206, 2019
6BNG	Structure of 2-dehydro-3-deoxyphosphooctonate aldolase from Acinetobacter baumannii 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-11-16 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of 2-dehydro-3-deoxyphosphooctonate aldolase from Acinetobacter baumannii to be published
2EF9	Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, ARABINOSE-5-PHOSPHATE, PHOSPHOENOLPYRUVATE 著者 Kona, F, Xu, X, Martin, P, Kuzmic, P, Gatti, D.L. 登録日 2007-02-22 公開日 2007-04-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Mechanistic Changes along an Engineered Path from Metallo to Nonmetallo 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthases Biochemistry, 46, 2007
5D09	Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Phe211Ala variant 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... 著者 Heyes, L.C, Parker, E.J. 登録日 2015-08-02 公開日 2016-08-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Phe211Ala variant at 2.35 Angstroms resolution To Be Published
5DCD	Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase regulated (Tyrosine) 分子名称: MANGANESE (II) ION, Phospho-2-dehydro-3-deoxyheptonate aldolase, SULFATE ION, ... 著者 Heyes, L.C, Parker, E. 登録日 2015-08-24 公開日 2016-08-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structure of Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase regulated and complexed with PEP at 2.05 Angstroms To Be Published
5CZ0	Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu98Ala variant 分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... 著者 Heyes, L.C, Parker, E.J. 登録日 2015-07-31 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 NmeDAH7PS E98A variant at 2.5 Angstroms resolution To Be Published
5CZT	Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu176Ala variant 分子名称: CHLORIDE ION, MANGANESE (II) ION, PHENYLALANINE, ... 著者 Heyes, L.C, Parker, E.J. 登録日 2015-08-01 公開日 2016-08-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu176Ala variant at 2.04 Angstroms resolution To Be Published
5D04	Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Val223Ala variant regulated 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Heyes, L.C, Parker, E.J. 登録日 2015-08-02 公開日 2016-08-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Val223Ala variant regulated at 1.70 Angstroms resolution To Be Published
4UMB	Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water 分子名称: (2R)-2-(phosphonooxy)propanoic acid, MANGANESE (II) ION, PHOSPHATE ION, ... 著者 Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J. 登録日 2014-05-16 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water. Bioorg.Chem., 57, 2014
4UMC	Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water 分子名称: L-PHOSPHOLACTATE, MANGANESE (II) ION, PHOSPHATE ION, ... 著者 Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J. 登録日 2014-05-16 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water. Bioorg.Chem., 57, 2014
4UC5	Neisseria Meningitidis DAH7PS-Phenylalanine regulated 分子名称: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, PHENYLALANINE, ... 著者 Heyes, L.C, Lang, E.J.M, Parker, E.J. 登録日 2014-12-03 公開日 2015-11-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Calculated Pka Variations Expose Dynamic Allosteric Communication Networks. J.Am.Chem.Soc., 138, 2016

 

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