4L02
 
 | | Crystal Structure of SphK1 with inhibitor | | 分子名称: | (2R,4S)-1-[2-(4-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]amino}phenyl)ethyl]-2-(hydroxymethyl)piperidin-4-ol, Sphingosine kinase 1 | | 著者 | Min, X, Walker, N, Wang, Z. | | 登録日 | 2013-05-30 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure guided design of a series of sphingosine kinase (SphK) inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
|
|
4V24
 | | Sphingosine kinase 1 in complex with PF-543 | | 分子名称: | ACETATE ION, SPHINGOSINE KINASE 1, {(2R)-1-[4-({3-METHYL-5-[(PHENYLSULFONYL)METHYL]PHENOXY}METHYL)BENZYL]PYRROLIDIN-2-YL}METHANOL | | 著者 | Elkins, J.M, Wang, J, Sorrell, F, Tallant, C, Wang, D, Shrestha, L, Bountra, C, von Delft, F, Knapp, S, Edwards, A. | | 登録日 | 2014-10-05 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Sphingosine Kinase 1 with Pf-543.
Acs Med.Chem.Lett., 5, 2014
|
|
3VZD
 | | Crystal structure of Sphingosine Kinase 1 with inhibitor and ADP | | 分子名称: | 4-{[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino}phenol, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Min, X, Walker, N.P, Wang, Z. | | 登録日 | 2012-10-11 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular basis of sphingosine kinase 1 substrate recognition and catalysis.
Structure, 21, 2013
|
|
3VZB
 | | Crystal structure of Sphingosine Kinase 1 | | 分子名称: | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, 1,2-ETHANEDIOL, SULFATE ION, ... | | 著者 | Min, X, Walker, N.P, Wang, Z. | | 登録日 | 2012-10-10 | | 公開日 | 2013-05-08 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis of sphingosine kinase 1 substrate recognition and catalysis.
Structure, 21, 2013
|
|
3VZC
 | | Crystal structure of Sphingosine Kinase 1 with inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino}phenol, Sphingosine kinase 1 | | 著者 | Min, X, Walker, N.P, Wang, Z. | | 登録日 | 2012-10-11 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular basis of sphingosine kinase 1 substrate recognition and catalysis.
Structure, 21, 2013
|
|
2BON
 | | Structure of an Escherichia coli lipid kinase (YegS) | | 分子名称: | LIPID KINASE, MAGNESIUM ION | | 著者 | Bakali, H.M, Johnson, K.A, Hallberg, B.M, Herman, M.D, Nordlund, P. | | 登録日 | 2005-04-12 | | 公開日 | 2006-10-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Yegs, a Homologue to the Mammalian Diacylglycerol Kinases, Reveals a Novel Regulatory Metal Binding Site.
J.Biol.Chem., 282, 2007
|
|
7CGP
 | | Cryo-EM structure of the human mitochondrial translocase TIM22 complex at 3.7 angstrom. | | 分子名称: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acylglycerol kinase, mitochondrial, ... | | 著者 | Qi, L, Wang, Q, Guan, Z, Yan, C, Yin, P. | | 登録日 | 2020-07-01 | | 公開日 | 2020-10-14 | | 最終更新日 | 2021-03-17 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of the human mitochondrial translocase TIM22 complex.
Cell Res., 31, 2021
|
|
2JGR
 | | Crystal structure of YegS in complex with ADP | | 分子名称: | PYROPHOSPHATE 2-, YEGS | | 著者 | Bakali, H.M, Herman, M.D, Johnson, K.A, Kelly, A.A, Wieslander, A, Hallberg, B.M, Nordlund, P. | | 登録日 | 2007-02-14 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of Yegs, a Homologue to the Mammalian Diacylglycerol Kinases, Reveals a Novel Regulatory Metal Binding Site.
J.Biol.Chem., 282, 2007
|
|
3S40
 | | The crystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne | | 分子名称: | diacylglycerol kinase | | 著者 | Tan, K, Zhang, R, Xu, X, Cui, H, Peterson, S, Savchenko, A, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-05-18 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne
To be Published
|
|
4WER
 | | Crystal structure of diacylglycerol kinase catalytic domain protein from Enterococcus faecalis V583 | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Diacylglycerol kinase catalytic domain protein | | 著者 | Chang, C, Clancy, S, Hatzos-Skintges, C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-09-10 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of diacylglycerol kinase catalytic domain protein from Enterococcus faecalis V583
To Be Published
|
|
4WRR
 | | A putative diacylglycerol kinase from Bacillus anthracis str. Sterne | | 分子名称: | MAGNESIUM ION, putative diacylglycerol kinase | | 著者 | Hou, J, Zheng, H, Cooper, D.R, Zimmerman, M.D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-10-24 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne
to be published
|
|
2P1R
 | | Crystal structure of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases. | | 分子名称: | CALCIUM ION, CHLORIDE ION, Lipid kinase yegS, ... | | 著者 | Nichols, C.E, Lamb, H.K, Lockyer, M, Charles, I.G, Pyne, S, Hawkins, A.R, Stammers, D.K. | | 登録日 | 2007-03-06 | | 公開日 | 2007-10-23 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Characterization of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases
Proteins: Struct.,Funct.,Genet., 68, 2007
|
|
2QV7
 | | Crystal Structure of Diacylglycerol Kinase DgkB in complex with ADP and Mg | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Diacylglycerol Kinase DgkB, MAGNESIUM ION | | 著者 | Miller, D.J, Jerga, A, Rock, C.O, White, S.W. | | 登録日 | 2007-08-07 | | 公開日 | 2008-06-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases.
Structure, 16, 2008
|
|
2QVL
 | |
3T5P
 | | Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne | | 分子名称: | BmrU protein, MAGNESIUM ION | | 著者 | Hou, J, Zheng, H, Chruszcz, M, Cooper, D.R, Onopriyenko, O, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-07-27 | | 公開日 | 2011-09-07 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne
To be Published
|
|
