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1N1F
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Crystal Structure of Human Interleukin-19
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, interleukin-19
著者Chang, C, Magracheva, E, Kozlov, S, Fong, S, Tobin, G, Kotenko, S, Wlodawer, A, Zdanov, A.
登録日2002-10-17
公開日2003-02-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of interleukin-19 defines a new subfamily of helical cytokines
J.Biol.Chem., 278, 2003
4X51
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X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y
分子名称: Interleukin-10
著者Kuenze, G.
登録日2014-12-04
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y
To Be Published
2H24
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Crystal structure of human IL-10
分子名称: Interleukin-10
著者Yoon, S.I, Walter, M.R.
登録日2006-05-18
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.
J.Biol.Chem., 281, 2006
2ILK
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CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN-10 AT 1.6 ANGSTROMS RESOLUTION
分子名称: INTERLEUKIN-10, SULFATE ION
著者Zdanov, A, Schalk-Hihi, C, Wlodawer, A.
登録日1996-07-01
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of human interleukin-10 at 1.6 A resolution and a model of a complex with its soluble receptor.
Protein Sci., 5, 1996
1VLK
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STRUCTURE OF VIRAL INTERLEUKIN-10
分子名称: VIRAL INTERLEUKIN-10
著者Zdanov, A, Schalk-Hihi, C, Wlodawer, A.
登録日1997-02-14
公開日1997-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Epstein-Barr virus protein BCRF1, a homolog of cellular interleukin-10.
J.Mol.Biol., 268, 1997
1ILK
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INTERLEUKIN-10 CRYSTAL STRUCTURE REVEALS THE FUNCTIONAL DIMER WITH AN UNEXPECTED TOPOLOGICAL SIMILARITY TO INTERFERON GAMMA
分子名称: INTERLEUKIN-10
著者Zdanov, A, Schalk-Hihi, C, Gustchina, A, Wlodawer, A.
登録日1995-04-21
公開日1995-07-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma.
Structure, 3, 1995
1INR
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CYTOKINE SYNTHESIS
分子名称: INTERLEUKIN-10
著者Walter, M.R.
登録日1995-07-31
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of interleukin 10 reveals an interferon gamma-like fold.
Biochemistry, 34, 1995
6X93
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Interleukin-10 signaling complex with IL-10RA and IL-10RB
分子名称: Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta
著者Saxton, R.A, Tsutsumi, N, Gati, C, Garcia, K.C.
登録日2020-06-02
公開日2021-03-17
最終更新日2021-03-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.
Science, 371, 2021
4DOH
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IL20/IL201/IL20R2 Ternary Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-20, Interleukin-20 receptor subunit alpha, ...
著者Logsdon, N.J, Walter, M.R.
登録日2012-02-09
公開日2012-07-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.
Proc.Natl.Acad.Sci.USA, 109, 2012
1Y6M
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Crystal structure of Epstein-Barr virus IL-10 complexed with the soluble IL-10R1 chain
分子名称: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
著者Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
登録日2004-12-06
公開日2005-05-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1Y6K
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Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain
分子名称: Interleukin-10, Interleukin-10 receptor alpha chain
著者Yoon, S.I, Jones, B.C, Josepson, K, Logsdon, N.J, Walter, M.R.
登録日2004-12-06
公開日2005-12-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1Y6N
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Crystal structure of Epstein-Barr virus IL-10 mutant (A87I) complexed with the soluble IL-10R1 chain
分子名称: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
著者Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
登録日2004-12-06
公開日2005-05-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1J7V
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HUMAN IL-10 / IL-10R1 COMPLEX
分子名称: INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN
著者Josephson, K, Logsdon, N, Walter, M.R.
登録日2001-05-18
公開日2001-09-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.
Immunity, 15, 2001
1LK3
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ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT
分子名称: 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10
著者Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R.
登録日2002-04-23
公開日2002-07-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography.
Structure, 10, 2002
1LQS
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CRYSTAL STRUCTURE OF HUMAN CYTOMEGALOVIRUS IL-10 BOUND TO SOLUBLE HUMAN IL-10R1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN, INTERLEUKIN-10-LIKE PROTEIN
著者Jones, B.C, Logsdon, N.J, Josephson, K, Cook, J, Barry, P.A, Walter, M.R.
登録日2002-05-13
公開日2002-07-17
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1.
Proc.Natl.Acad.Sci.USA, 99, 2002

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