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4XWK
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BU of 4xwk by Molmil
P-glycoprotein co-crystallized with BDE-100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, Multidrug resistance protein 1A
著者McGrath, A.P, Rees, S.D, Chang, G.
登録日2015-01-28
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure.
Sci Adv, 2, 2016
2ONJ
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BU of 2onj by Molmil
Structure of the multidrug ABC transporter Sav1866 from S. aureus in complex with AMP-PNP
分子名称: Multidrug export ATP-binding/permease protein SAV1866, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION
著者Dawson, R.J.P, Locher, K.P.
登録日2007-01-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP.
Febs Lett., 581, 2007
2HYD
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BU of 2hyd by Molmil
Multidrug ABC transporter SAV1866
分子名称: ABC transporter homolog, ADENOSINE-5'-DIPHOSPHATE, SODIUM ION
著者Dawson, R.J.P, Locher, K.P.
登録日2006-08-05
公開日2006-09-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a bacterial multidrug ABC transporter.
Nature, 443, 2006
3QF4
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BU of 3qf4 by Molmil
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ...
著者Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A.
登録日2011-01-21
公開日2012-03-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Nat.Struct.Mol.Biol., 19, 2012
6VQU
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BU of 6vqu by Molmil
Structure of a bacterial Atm1-family ABC exporter
分子名称: ATM1-type heavy metal exporter
著者Fan, C, Rees, D.C.
登録日2020-02-05
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VQT
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BU of 6vqt by Molmil
Structure of a bacterial Atm1-family ABC exporter with MgADPVO4 bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION, ...
著者Fan, C, Rees, D.C.
登録日2020-02-05
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
3G60
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BU of 3g60 by Molmil
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
分子名称: (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a
著者Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
登録日2009-02-05
公開日2009-03-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
5OFR
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BU of 5ofr by Molmil
Structure of the antibacterial peptide ABC transporter McjD in a high energy outward occluded intermediate state
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
著者Beis, K, Bountra, K.
登録日2017-07-11
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
3G5U
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BU of 3g5u by Molmil
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
分子名称: MERCURY (II) ION, Multidrug resistance protein 1a
著者Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
登録日2009-02-05
公開日2009-03-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
5OCH
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BU of 5och by Molmil
The crystal structure of human ABCB8 in an outward-facing state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 8, mitochondrial, ...
著者Faust, B, Pike, A.C.W, Shintre, C.A, Quiqley, A.M, Chu, A, Barr, A, Shrestha, L, Mukhopadhyay, S, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
登録日2017-06-30
公開日2018-07-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The crystal structure of human ABCB8 in an outward-facing state
To Be Published
5OFP
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BU of 5ofp by Molmil
Structure of the antibacterial peptide ABC transporter McjD in an apo inward occluded conformation
分子名称: Microcin-J25 export ATP-binding/permease protein McjD
著者Beis, K, Choudhury, H.G.
登録日2017-07-11
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.71 Å)
主引用文献Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
3G61
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BU of 3g61 by Molmil
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
分子名称: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a
著者Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
登録日2009-02-05
公開日2009-03-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.35 Å)
主引用文献Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
3WMG
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BU of 3wmg by Molmil
Crystal structure of an inward-facing eukaryotic ABC multidrug transporter G277V/A278V/A279V mutant in complex with an cyclic peptide inhibitor, aCAP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-binding cassette, sub-family B, ...
著者Kodan, A, Yamaguchi, T, Nakatsu, T, Sakiyama, K, Hipolito, C.J, Fujioka, A, Hirokane, R, Ikeguchi, K, Watanabe, B, Hirtake, J, Kimura, Y, Suga, H, Ueda, K, Kato, H.
登録日2013-11-18
公開日2014-04-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WME
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BU of 3wme by Molmil
Crystal structure of an inward-facing eukaryotic ABC multidrug transporter
分子名称: ATP-binding cassette, sub-family B, member 1, ...
著者Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H.
登録日2013-11-18
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WMF
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BU of 3wmf by Molmil
Crystal structure of an inward-facing eukaryotic ABC multitrug transporter G277V/A278V/A279V mutant
分子名称: ATP-binding cassette, sub-family B, member 1, ...
著者Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H.
登録日2013-11-18
公開日2014-03-19
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
4F4C
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BU of 4f4c by Molmil
The Crystal Structure of the Multi-Drug Transporter
分子名称: Multidrug resistance protein pgp-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
著者Jin, M.S, Oldham, M.L, Zhang, Q, Chen, J.
登録日2012-05-10
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.
Nature, 490, 2012
5C76
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BU of 5c76 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward facing state (2)
分子名称: WlaB protein
著者Perez, C, Gerber, S, Locher, K.P.
登録日2015-06-24
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.94 Å)
主引用文献Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5C73
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BU of 5c73 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in outward-occluded conformation
分子名称: Protein glycosylation K
著者Perez, C, Locher, K.P.
登録日2015-06-24
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5C78
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BU of 5c78 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward state (1)
分子名称: ATP-driven flippase PglK, PENTAETHYLENE GLYCOL
著者Perez, C, Locher, K.P.
登録日2015-06-24
公開日2015-08-19
最終更新日2015-09-02
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5EG1
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BU of 5eg1 by Molmil
Antibacterial peptide ABC transporter McjD with a resolved lipid
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
著者Choudhury, H.G, Beis, K.
登録日2015-10-26
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.
J.Biol.Chem., 291, 2016
4KSD
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BU of 4ksd by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
分子名称: Multidrug resistance protein 1A, R2 protein
著者Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
登録日2013-05-17
公開日2013-07-31
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (4.1001 Å)
主引用文献Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSC
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BU of 4ksc by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
分子名称: Multidrug resistance protein 1A
著者Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
登録日2013-05-17
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSB
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BU of 4ksb by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
分子名称: Multidrug resistance protein 1A
著者Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
登録日2013-05-17
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8001 Å)
主引用文献Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
6C0V
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BU of 6c0v by Molmil
Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1
著者Kim, Y.J, Chen, J.
登録日2018-01-02
公開日2018-01-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation.
Science, 359, 2018
6C3P
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BU of 6c3p by Molmil
Cryo-EM structure of human KATP bound to ATP and ADP in propeller form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Lee, K.P.K, Chen, J, MacKinnon, R.
登録日2018-01-10
公開日2018-01-24
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017

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