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7Z8B
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BU of 7z8b by Molmil
Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation
分子名称: Cullin-7, E3 ubiquitin-protein ligase RBX1, F-box/WD repeat-containing protein 8, ...
著者Hopf, L.V.M, Schulman, B.A.
登録日2022-03-17
公開日2022-08-24
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.
Nat.Struct.Mol.Biol., 29, 2022
3L2O
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BU of 3l2o by Molmil
Structure-Based Mechanism of Dimerization-Dependent Ubiquitination by the SCFFbx4 Ubiquitin Ligase
分子名称: F-box only protein 4, S-phase kinase-associated protein 1
著者Li, Y, Hao, B.
登録日2009-12-15
公開日2010-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase.
J.Biol.Chem., 285, 2010
2E31
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BU of 2e31 by Molmil
Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase
分子名称: F-box only protein 2, S-phase kinase-associated protein 1A
著者Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K.
登録日2006-11-20
公開日2007-03-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E32
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BU of 2e32 by Molmil
Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase
分子名称: F-box only protein 2, S-phase kinase-associated protein 1A
著者Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K.
登録日2006-11-20
公開日2007-03-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
3C6O
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BU of 3c6o by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
分子名称: (2S)-2-(1H-indol-3-yl)hexanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
著者Tan, X.
登録日2008-02-04
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C6N
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BU of 3c6n by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
分子名称: (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
著者Tan, X, Zheng, N, Hayashi, K.
登録日2008-02-04
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C6P
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BU of 3c6p by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
分子名称: (2S)-2-(1H-indol-3-yl)pentanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
著者Tan, X.
登録日2008-02-04
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2P1P
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BU of 2p1p by Molmil
Mechanism of Auxin Perception by the TIR1 ubiquitin ligase
分子名称: 1H-INDOL-3-YLACETIC ACID, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
著者Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
2P1N
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BU of 2p1n by Molmil
Mechanism of Auxin Perception by the TIR1 Ubiqutin Ligase
分子名称: (2,4-DICHLOROPHENOXY)ACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ...
著者Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, C, Zheng, N.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
2P1O
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BU of 2p1o by Molmil
Mechanism of Auxin Perception by the TIR1 ubiquitin ligase
分子名称: Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, NAPHTHALEN-1-YL-ACETIC ACID, ...
著者Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
2P1M
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BU of 2p1m by Molmil
TIR1-ASK1 complex structure
分子名称: INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, TRANSPORT INHIBITOR RESPONSE 1 protein
著者Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
登録日2007-03-05
公開日2007-04-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
2P1Q
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BU of 2p1q by Molmil
Mechanism of Auxin Perception by the TIR1 ubiquitin ligase
分子名称: 1H-INDOL-3-YLACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ...
著者Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Mechanism of auxin perception by the TIR1 ubiquitin ligase.
Nature, 446, 2007
8S4G
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BU of 8s4g by Molmil
Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2024-02-21
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex
To Be Published
7QE7
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BU of 7qe7 by Molmil
High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2021-12-01
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
1NEX
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BU of 1nex by Molmil
Crystal Structure of ScSkp1-ScCdc4-CPD peptide complex
分子名称: CDC4 protein, Centromere DNA-binding protein complex CBF3 subunit D, GLL(TPO)PPQSG
著者Orlicky, S, Tang, X, Willems, A, Tyers, M, Sicheri, F.
登録日2002-12-12
公開日2003-02-18
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCFCdc4 Ubiquitin Ligase
Cell(Cambridge,Mass.), 112, 2003
3MKS
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BU of 3mks by Molmil
Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2
分子名称: 1,1'-binaphthalene-2,2'-dicarboxylic acid, Cell division control protein 4, GLYCEROL, ...
著者Orlicky, S, Sicheri, F, Tyers, M, Tang, X.
登録日2010-04-15
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase.
Nat.Biotechnol., 28, 2010
6O60
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BU of 6o60 by Molmil
Crystal structure of GGTase3-FBXL2-SKP1 complex
分子名称: F-box/LRR-repeat protein 2, Geranylgeranyl transferase type-2 subunit beta, Protein prenyltransferase alpha subunit repeat-containing protein 1, ...
著者Wang, H, Zheng, N.
登録日2019-03-04
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.
Nat.Struct.Mol.Biol., 26, 2019
4UI9
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BU of 4ui9 by Molmil
Atomic structure of the human Anaphase-Promoting Complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2015-03-27
公開日2015-06-17
最終更新日2019-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
3V7D
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BU of 3v7d by Molmil
Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex
分子名称: Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1
著者Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M.
登録日2011-12-20
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109, 2012
7PMK
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BU of 7pmk by Molmil
S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)
分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
登録日2021-09-02
公開日2021-11-10
最終更新日2022-02-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PMN
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BU of 7pmn by Molmil
S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II)
分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
登録日2021-09-02
公開日2021-11-10
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
6C16
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BU of 6c16 by Molmil
Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.
分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2018-01-04
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6BYH
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BU of 6byh by Molmil
Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.
分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2017-12-20
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018

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