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6NUI
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Human Guanylate Kinase
分子名称: Guanylate kinase
著者Sabo, T.M, Khan, N, Ban, D, Trigo-Mourino, P, Carneiro, M.G, Trent, J.O, Konrad, M, Lee, D.
登録日2019-02-01
公開日2019-06-26
最終更新日2019-08-14
実験手法SOLUTION NMR
主引用文献Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.
J.Biol.Chem., 294, 2019
3NEY
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BU of 3ney by Molmil
Crystal structure of the kinase domain of MPP1/p55
分子名称: 55 kDa erythrocyte membrane protein, SULFATE ION, UNKNOWN ATOM OR ION
著者Shen, Y, Tong, Y, Zhong, N, Guan, X, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2010-06-09
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of the kinase domain of MPP1/p55
To be Published
6WCT
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BU of 6wct by Molmil
Crystal structure of a guanylate kinase from Stenotrophomonas maltophilia K279a bound to guanosine-5'-monophosphate
分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-03-31
公開日2020-04-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a guanylate kinase from Stenotrophomonas maltophilia K279a bound to guanosine-5'-monophosphate
To Be Published
2J41
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Crystal structure of Staphylococcus aureus guanylate monophosphate kinase
分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANYLATE KINASE, POTASSIUM ION, ...
著者El Omari, K, Dhaliwal, B, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K.
登録日2006-08-24
公開日2006-10-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Staphylococcus Aureus Guanylate Monophosphate Kinase
Acta Crystallogr.,Sect.F, 62, 2006
2QOR
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Crystal structure of Plasmodium vivax guanylate kinase
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, PYROPHOSPHATE 2-
著者Merritt, E.A, Le Trong, I, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2007-07-20
公開日2007-08-07
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Plasmodium vivax guanylate kinase.
To be Published
4QRH
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Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp
分子名称: 1,2-ETHANEDIOL, Guanylate kinase, MAGNESIUM ION, ...
著者Liu, K, Krasny, K, Myers, A.R, Satyshur, K.A, Keck, J.L, Wnag, J.D.
登録日2014-07-01
公開日2015-02-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp.
Mol.Cell, 57, 2015
7F7G
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a linear Peptide Inhibitors in complex with GK domain
分子名称: DLG4 GK domain, UNK-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYS-ALA-ILE-GLN-UNK
著者Shang, Y, Huang, X, Li, X, Zhang, M.
登録日2021-06-29
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.446 Å)
主引用文献Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Rsc Chem Biol, 2, 2021
7F7I
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Stapled Peptide Inhibitor in complex with PSD95 GK domain
分子名称: ACE-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYZ-ALA-ILE-GLN-NH2, Disks large homolog 4
著者Shang, Y, Huang, X, Li, X, Zhang, M.
登録日2021-06-29
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.595 Å)
主引用文献Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Rsc Chem Biol, 2, 2021
1EX6
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CRYSTAL STRUCTURE OF UNLIGANDED FORM OF GUANYLATE KINASE FROM YEAST
分子名称: GUANYLATE KINASE
著者Blaszczyk, J, Ji, X.
登録日2000-05-01
公開日2001-03-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of unligated guanylate kinase from yeast reveals GMP-induced conformational changes.
J.Mol.Biol., 307, 2001
1EX7
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CRYSTAL STRUCTURE OF YEAST GUANYLATE KINASE IN COMPLEX WITH GUANOSINE-5'-MONOPHOSPHATE
分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANYLATE KINASE, SULFATE ION
著者Blaszczyk, J, Ji, X.
登録日2000-05-01
公開日2001-03-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of unligated guanylate kinase from yeast reveals GMP-induced conformational changes.
J.Mol.Biol., 307, 2001
1GKY
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REFINED STRUCTURE OF THE COMPLEX BETWEEN GUANYLATE KINASE AND ITS SUBSTRATE GMP AT 2.0 ANGSTROMS RESOLUTION
分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANYLATE KINASE, SULFATE ION
著者Stehle, T, Schulz, G.E.
登録日1991-12-23
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refined structure of the complex between guanylate kinase and its substrate GMP at 2.0 A resolution.
J.Mol.Biol., 224, 1992
5GNV
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Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain
分子名称: Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION
著者Shang, Y, Xia, Y, Zhu, R, Zhu, J.
登録日2016-07-25
公開日2017-08-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain
Biochem. J., 474, 2017
4F4J
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Conversion of the enzyme guanylate kinase into a mitotic spindle orienting protein by a single mutation that inhibits gmp- induced closing
分子名称: Guanylate kinase, SULFATE ION
著者Johnston, C.A, Whitney, D, Volkman, B.F, Prehoda, K.E.
登録日2012-05-10
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing.
Proc.Natl.Acad.Sci.USA, 108, 2011
5YPO
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Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide
分子名称: Disks large homolog 4, GLYCEROL, SAPAP
著者Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhang, R, Zhang, M.
登録日2017-11-02
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
3LNC
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Crystal structure of guanylate kinase from Anaplasma phagocytophilum
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-02-02
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of guanylate kinase from Anaplasma phagocytophilum
TO BE PUBLISHED
7LUY
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Crystal Structure of guanylate kinase from Bartonella henselae str. Houston-1
分子名称: 1,2-ETHANEDIOL, Guanylate kinase, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-02-23
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of guanylate kinase from Bartonella henselae str. Houston-1
to be published
7S5E
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Crystal structure of a guanylate kinase from Stenotrophomonas maltophilia K279a with heterogeneous ligand states of GMP/ADP, GMP/-, GDP/-, and GMP/ATPgS
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-09-10
公開日2021-09-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a guanylate kinase from Stenotrophomonas maltophilia K279c with heterogeneous ligand states of GMP/ADP, GMP/-, GDP/-, and GMP/ATPgS.
To Be Published
2ANB
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Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION
著者Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J.
登録日2005-08-11
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase
J.Mol.Biol., 352, 2005
2ANC
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Crystal Structure Of Unliganded Form Of Oligomeric E.coli Guanylate Kinase
分子名称: Guanylate kinase
著者Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J.
登録日2005-08-11
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase
J.Mol.Biol., 352, 2005
2AN9
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Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GDP
分子名称: GUANOSINE, GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase, ...
著者Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J.
登録日2005-08-11
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase
J.Mol.Biol., 352, 2005
7U5F
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Crystal structure of guanylate kinase from Pseudomonas aeruginosa PAO1 in complex with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, MAGNESIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-03-02
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of guanylate kinase from Pseudomonas aeruginosa PAO1 in complex with GMP
To be Published
1KGD
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Crystal Structure of the Guanylate Kinase-like Domain of Human CASK
分子名称: FORMIC ACID, PERIPHERAL PLASMA MEMBRANE CASK
著者Li, Y, Spangenberg, O, Paarmann, I, Konrad, M, Lavie, A.
登録日2001-11-26
公開日2001-12-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.314 Å)
主引用文献Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains.
J.Biol.Chem., 277, 2002
1LVG
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Crystal structure of mouse guanylate kinase in complex with GMP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, ...
著者Sekulic, N, Shuvalova, L, Spangenberg, O, Konrad, M, Lavie, A.
登録日2002-05-28
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of the closed conformation of mouse guanylate kinase.
J.Biol.Chem., 277, 2002
6MFU
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Crystal structure of a Guanylate kinase from Cryptococcus neoformans var. grubii serotype A in complex with GDP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-09-12
公開日2018-09-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a Guanylate kinase from Cryptococcus neoformans var. grubii serotype A in complex with GDP and ADP
TO BE PUBLISHED
2F3T
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Crystal Structure Of E.coli Guanylate Kinase In Complex With Ganciclovir monophosphate
分子名称: Guanylate kinase, N9-1-HYDROXY-PROP-2-OXYMETHYL-GUANINE-3'-MONOPHOSPHATE
著者Hible, G, Cherfils, J.
登録日2005-11-22
公開日2006-05-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G.
Biochimie, 88, 2006

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