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6ZBK
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BU of 6zbk by Molmil
Crystal structure of the human complex between RPAP3 and TRBP
分子名称: RISC-loading complex subunit TARBP2, RNA polymerase II-associated protein 3
著者Charron, C, Abel, Y, Charpentier, B, Rederstorff, M.
登録日2020-06-08
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.
Nucleic Acids Res., 50, 2022
2BUG
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BU of 2bug by Molmil
Solution structure of the TPR domain from Protein phosphatase 5 in complex with Hsp90 derived peptide
分子名称: HSP90, SERINE/THREONINE PROTEIN PHOSPHATASE 5
著者Cliff, M.J, Harris, R, Barford, D, Ladbury, J.E, Williams, M.A.
登録日2005-06-13
公開日2006-03-16
最終更新日2020-01-15
実験手法SOLUTION NMR
主引用文献Conformational Diversity in the Tpr Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90.
Structure, 14, 2006
6I57
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BU of 6i57 by Molmil
NMR structure of the third TPR domain of the human SPAG1 protein
分子名称: Sperm-associated antigen 1
著者Chagot, M.E, Quinternet, M.
登録日2018-11-13
公開日2019-06-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Binding properties of the quaternary assembly protein SPAG1.
Biochem.J., 476, 2019
4CGV
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BU of 4cgv by Molmil
First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD
分子名称: GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, RNA POLYMERASE II-ASSOCIATED PROTEIN 3
著者Roe, S.M, Pal, M.
登録日2013-11-26
公開日2014-05-14
最終更新日2014-06-25
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
2KC7
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BU of 2kc7 by Molmil
Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
分子名称: bfr218_protein
著者Eletsky, A, Wu, Y, Sukumaran, D, Lee, H, Lee, D.Y, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2008-12-17
公開日2009-01-13
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
To be Published
2LNI
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BU of 2lni by Molmil
Solution NMR Structure of Stress-induced-phosphoprotein 1 STI1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4403E
分子名称: Stress-induced-phosphoprotein 1
著者Tang, Y, Liu, G, Hamilton, K, Ciccosanti, C, Shastry, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2011-12-28
公開日2012-03-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target HR4403E
To be Published
4GCO
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BU of 4gco by Molmil
Central domain of stress-induced protein-1 (STI-1) from C.elegans
分子名称: Protein STI-1
著者Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-07-30
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
3UQ3
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BU of 3uq3 by Molmil
TPR2AB-domain:pHSP90-complex of yeast Sti1
分子名称: Heat shock protein, Heat shock protein STI1
著者Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J.
登録日2011-11-19
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
3UPV
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BU of 3upv by Molmil
TPR2B-domain:pHsp70-complex of yeast Sti1
分子名称: Heat shock protein SSA4, Heat shock protein STI1
著者Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H.
登録日2011-11-18
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
6FD7
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BU of 6fd7 by Molmil
NMR structure of the first TPR domain of the human RPAP3 protein
分子名称: RNA polymerase II-associated protein 3
著者Quinternet, M, Chagot, M.E, Manival, X.
登録日2017-12-22
公開日2018-08-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
5LYP
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BU of 5lyp by Molmil
Crystal structure of the Tpr Domain of Sgt2.
分子名称: BORATE ION, Small glutamine-rich tetratricopeptide repeat-containing protein 2
著者Krysztofinska, E.M, Morgan, R.M.L, Thapaliya, A, Evans, N.J, Murray, J.W, Martinez-Lumbreras, S, Isaacson, R.L.
登録日2016-09-28
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
5LYN
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BU of 5lyn by Molmil
Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment
分子名称: PRO-THR-VAL-GLU-GLU-VAL-ASP, Small glutamine-rich tetratricopeptide repeat-containing protein 2, ZINC ION
著者Krysztofinska, E.M, Evans, N.J, Thapaliya, A, Murray, J.W, Morgan, R.M.L, Martinez-Lumbreras, S, Isaacson, R.L.
登録日2016-09-28
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
1A17
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BU of 1a17 by Molmil
TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5
分子名称: SERINE/THREONINE PROTEIN PHOSPHATASE 5, SULFATE ION
著者Das, A.K, Cohen, P.T.W, Barford, D.
登録日1997-12-23
公開日1998-04-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions.
EMBO J., 17, 1998
2NC9
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BU of 2nc9 by Molmil
Apo solution structure of Hop TPR2A
分子名称: Stress-induced-phosphoprotein 1
著者Darby, J.F, Vidler, L.R, Simpson, P.J, Matthews, S.J, Sharp, S.Y, Pearl, L.H, Hoelder, S, Workman, P.
登録日2016-03-23
公開日2017-03-29
最終更新日2020-10-28
実験手法SOLUTION NMR
主引用文献Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
Sci Rep, 10, 2020
1ELR
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BU of 1elr by Molmil
Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
分子名称: HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP
著者Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I.
登録日2000-03-14
公開日2000-04-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
Cell(Cambridge,Mass.), 101, 2000
8PKP
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BU of 8pkp by Molmil
Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2023-06-27
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
3FWV
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BU of 3fwv by Molmil
Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide
分子名称: Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION
著者Jackrel, M.E, Valverde, R, Regan, L.
登録日2009-01-19
公開日2009-04-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
3LCA
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BU of 3lca by Molmil
Structure of Tom71 complexed with Hsp70 Ssa1 C terminal tail indicating conformational plasticity
分子名称: GLYCEROL, Heat shock protein SSA1, Protein TOM71
著者Li, J.Z, Sha, B.D.
登録日2010-01-10
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The structural plasticity of Tom71 for mitochondrial precursor translocations.
Acta Crystallogr.,Sect.F, 66, 2010
3ZFW
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BU of 3zfw by Molmil
Crystal structure of the TPR domain of kinesin light chain 2 in complex with a tryptophan-acidic cargo peptide
分子名称: KINESIN LIGHT CHAIN 2, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2
著者Pernigo, S, Lamprecht, A, Steiner, R.A, Dodding, M.P.
登録日2012-12-12
公開日2013-04-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Kinesin-1:Cargo Recognition.
Science, 340, 2013
6HFT
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BU of 6hft by Molmil
Hsp90 co-chaperone Cns1 from Saccharomyces cerevisiae (delta69)
分子名称: Hsp70/Hsp90 co-chaperone CNS1, MAGNESIUM ION
著者Huber, E.M, Groll, M.
登録日2018-08-21
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
Mol.Cell, 74, 2019
5OJ8
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BU of 5oj8 by Molmil
Crystal structure of the KLC1-TPR domain ([A1-B5] fragment)
分子名称: Kinesin light chain 1, PHOSPHATE ION
著者Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J.
登録日2017-07-20
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.
PLoS ONE, 12, 2017
7NTF
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BU of 7ntf by Molmil
Cryo-EM structure of unliganded O-GlcNAc transferase
分子名称: Isoform 1 of UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
著者Meek, R.W, Blaza, J.N, Davies, G.J.
登録日2021-03-09
公開日2021-11-17
最終更新日2021-11-24
実験手法ELECTRON MICROSCOPY (5.32 Å)
主引用文献Cryo-EM structure provides insights into the dimer arrangement of the O-linked beta-N-acetylglucosamine transferase OGT.
Nat Commun, 12, 2021
3NF1
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BU of 3nf1 by Molmil
Crystal structure of the TPR domain of kinesin light chain 1
分子名称: Kinesin light chain 1
著者Tong, Y, Tempel, W, Shen, L, Shen, Y, Nedyalkova, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2010-06-09
公開日2011-05-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the TPR domain of kinesin light chain 1
to be published
3IEG
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BU of 3ieg by Molmil
Crystal Structure of P58(IPK) TPR Domain at 2.5 A
分子名称: DnaJ homolog subfamily C member 3
著者Tao, J, Sha, B.
登録日2009-07-22
公開日2010-03-31
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPR.
J.Mol.Biol., 64, 2010
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
分子名称: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
著者Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
登録日2004-07-14
公開日2004-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004

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