PDB: 189 件ウェブページステータス検索Chemie searchBIRD

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6DKT	Crystal structure of Arginase from Bacillus subtilis 分子名称: Arginase, MANGANESE (II) ION 著者 Lewis, M.C, Hollingsworth, S.A, Holden, J.K, Poulos, T.L. 登録日 2018-05-30 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structure of Arginase from Bacillus subtilis at 2.08 Angstroms resolution To Be Published
7OI1	Crystal structure of Synechocystis sp PCC6803 guanidinium hydrolase 分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ... 著者 Fleming, J.R, Mayans, O.M. 登録日 2021-05-11 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a Ni 2+ -dependent guanidine hydrolase in bacteria. Nature, 603, 2022
5RLA	ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION 分子名称: ARGINASE, MANGANESE (II) ION 著者 Scolnick, L.R, Kanyo, Z.F, Christianson, D.W. 登録日 1997-05-07 公開日 1998-05-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function. Biochemistry, 36, 1997
2ZAV	Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolution 分子名称: Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Christianson, D.W. 登録日 2007-10-11 公開日 2007-10-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster J.Am.Chem.Soc., 129, 2007
5CEV	ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX 分子名称: GUANIDINE, LYSINE, MANGANESE (II) ION, ... 著者 Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. 登録日 1999-03-16 公開日 1999-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
5YNL	Crystal structure of a cold-adapted arginase from psychrophilic yeast, Glaciozyma antarctica 分子名称: Arginase 著者 Yusof, N.Y, Quay, D.H.X, Illias, R.M, Firdaus-Raih, M, Abu-Bakar, F.D, Mahadi, N.M, Murad, A.M.A. 登録日 2017-10-24 公開日 2018-01-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Crystal structure of a cold-adapted arginase from psychrophilic yeast, Glaciozyma antarctica To Be Published
5HJ9	Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE 分子名称: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... 著者 Hai, Y, Christianson, D.W. 登録日 2016-01-13 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors. Acta Crystallogr F Struct Biol Commun, 72, 2016
5HJA	Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHDP 分子名称: (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid, Arginase, GLYCEROL, ... 著者 Hai, Y, Christianson, D.W. 登録日 2016-01-13 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors. Acta Crystallogr F Struct Biol Commun, 72, 2016
1D3V	CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG 分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE) 著者 Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W. 登録日 1999-10-01 公開日 1999-11-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Arginase-boronic acid complex highlights a physiological role in erectile function. Nat.Struct.Biol., 6, 1999
1CEV	ARGINASE FROM BACILLUS CALDOVELOX, NATIVE STRUCTURE AT PH 5.6 分子名称: MANGANESE (II) ION, PROTEIN (ARGINASE) 著者 Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. 登録日 1999-03-12 公開日 1999-04-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
8E5M	Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6 分子名称: 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION 著者 Palte, R.L, Gathiaka, S. 登録日 2022-08-22 公開日 2023-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods. Bioorg.Med.Chem.Lett., 84, 2023
8E5N	Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 10 分子名称: 1-{[(3S,4S)-3-(3-fluorophenyl)-4-{[4-(1,3,4-triethyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl}pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION 著者 Palte, R.L, Gathiaka, S. 登録日 2022-08-22 公開日 2023-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.538 Å) 主引用文献 Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods. Bioorg.Med.Chem.Lett., 84, 2023
5ZEF	Crystal structure of Entamoeba histolytica Arginase in complex with L- Norvaline at 2.01 A 分子名称: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... 著者 Malik, A, Dalal, V, Ankri, S, Tomar, S. 登録日 2018-02-27 公開日 2019-06-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286, 2019
5ZEH	Crystal structure of Entamoeba histolytica Arginase in complex with L- Ornithine at 2.35 A 分子名称: 1,2-ETHANEDIOL, Arginase, L-ornithine, ... 著者 Malik, A, Dalal, V, Ankri, S, Tomar, S. 登録日 2018-02-27 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286, 2019
8AUP	Structure of hARG1 with a novel inhibitor. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, ... 著者 Napiorkowska-Gromadzka, A, Nowak, E, Nowotny, M. 登録日 2022-08-25 公開日 2023-03-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy. Mol.Cancer Ther., 22, 2023
5ZEE	Crystal structure of Entamoeba histolytica Arginase in complex with N(omega)-hydroxy-L-arginine (NOHA) at 1.74 A 分子名称: 1,2-ETHANEDIOL, Arginase, MANGANESE (II) ION, ... 著者 Malik, A, Dalal, V, Ankri, S, Tomar, S. 登録日 2018-02-27 公開日 2019-06-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286, 2019
8C0H	Crystal structure of guanidinase from Nitrospira inopinata 分子名称: NICKEL (II) ION, Putative agmatinase 2, SULFATE ION 著者 Puehringer, D. 登録日 2022-12-16 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Growth of complete ammonia oxidizers on guanidine To Be Published
8D27	Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum 分子名称: Arginase 著者 Chan, A.C, Kolesnikov, M, Murphy, M.E. 登録日 2022-05-27 公開日 2022-07-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry, 61, 2022
6KSY	Crystal structure of arginase from Zymomonas mobilis ZM4 分子名称: Arginase/agmatinase/formiminoglutamase, ZINC ION 著者 Park, S.Y, Hwangbo, S.A. 登録日 2019-08-26 公開日 2020-08-05 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.649 Å) 主引用文献 Characterization of a Dimeric Arginase FromZymomonas mobilisZM4. Front Microbiol, 10, 2019
6LUH	High resolution structure of N(omega)-hydroxy-L-arginine hydrolase 分子名称: MAGNESIUM ION, MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase 著者 Oda, K, Matoba, Y. 登録日 2020-01-28 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of an Nomega-hydroxy-L-arginine hydrolase found in the D-cycloserine biosynthetic pathway. Acta Crystallogr D Struct Biol, 76, 2020
6LUG	Crystal structure of N(omega)-hydroxy-L-arginine hydrolase 分子名称: MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase 著者 Oda, K, Matoba, Y. 登録日 2020-01-28 公開日 2020-06-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of an Nomega-hydroxy-L-arginine hydrolase found in the D-cycloserine biosynthetic pathway. Acta Crystallogr D Struct Biol, 76, 2020
4CEV	ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX 分子名称: GUANIDINE, L-ornithine, MANGANESE (II) ION, ... 著者 Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. 登録日 1999-03-15 公開日 1999-04-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
2PHA	Crystal structure of native, unliganded human arginase at 1.90 resolution 分子名称: Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Pique, M.E, Christianson, D.W. 登録日 2007-04-10 公開日 2007-05-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster. J.Am.Chem.Soc., 129, 2007
2PLL	Crystal structure of perdeuterated human arginase I 分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, arginase-1 著者 Di Costanzo, L, Moulin, M, Haertlein, M, Meilleur, F, Christianson, D.W. 登録日 2007-04-19 公開日 2007-08-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Expression, purification, assay, and crystal structure of perdeuterated human arginase I Arch.Biochem.Biophys., 465, 2007
2PHO	Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution 分子名称: Arginase-1, HYDRAZINECARBOTHIOAMIDE, MANGANESE (II) ION 著者 Di Costanzo, L, Christianson, D.W. 登録日 2007-04-11 公開日 2007-05-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster. J.Am.Chem.Soc., 129, 2007

 

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