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1AK5
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, SULFATE ION
著者Whitby, F.G.
登録日1997-05-28
公開日1997-09-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex.
Biochemistry, 36, 1997
1B3O
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TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE
分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), ...
著者Colby, T.D, Vanderveen, K, Strickler, M.D, Goldstein, B.M.
登録日1998-12-14
公開日1999-04-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.
Proc.Natl.Acad.Sci.USA, 96, 1999
1ZFJ
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH; EC 1.1.1.205) FROM STREPTOCOCCUS PYOGENES
分子名称: INOSINE MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID
著者Zhang, R, Evans, G, Rotella, F.J, Westbrook, E.M, Beno, D, Huberman, E, Joachimiak, A, Collart, F.R.
登録日1999-03-29
公開日2000-03-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase.
Biochemistry, 38, 1999
1EEP
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2.4 A RESOLUTION CRYSTAL STRUCTURE OF BORRELIA BURGDORFERI INOSINE 5'-MONPHOSPHATE DEHYDROGENASE IN COMPLEX WITH A SULFATE ION
分子名称: INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE, SULFATE ION
著者McMillan, F.M, Cahoon, M, White, A, Hedstrom, L, Petsko, G.A, Ringe, D.
登録日2000-02-01
公開日2000-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
Biochemistry, 39, 2000
1JR1
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Crystal structure of Inosine Monophosphate Dehydrogenase in complex with Mycophenolic Acid
分子名称: INOSINIC ACID, Inosine-5'-Monophosphate Dehydrogenase 2, MYCOPHENOLIC ACID, ...
著者Sintchak, M.D, Fleming, M.A, Futer, O, Raybuck, S.A, Chambers, S.P, Caron, P.R, Murcko, M.A, Wilson, K.P.
登録日2001-08-09
公開日2001-09-05
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.
Cell(Cambridge,Mass.), 85, 1996
1ME8
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP bound
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ...
著者Prosise, G.L, Wu, J, Luecke, H.
登録日2002-08-08
公開日2003-01-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
J.Biol.Chem., 277, 2002
1ME7
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP and MOA bound
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ...
著者Prosise, G.L, Wu, J, Luecke, H.
登録日2002-08-08
公開日2003-01-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
J.Biol.Chem., 277, 2002
1JCN
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BINARY COMPLEX OF HUMAN TYPE-I INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP
分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, INOSINE MONOPHOSPHATE DEHYDROGENASE I
著者Risal, D, Strickler, M.D, Goldstein, B.M.
登録日2001-06-11
公開日2003-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Human Type I Inosine Monophosphate Dehydrogenase and Implications for Isoform Specificity
To be Published
1LRT
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CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, ...
著者Gan, L, Petsko, G.A, Hedstrom, L.
登録日2002-05-15
公開日2003-07-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis
Biochemistry, 41, 2003
1PVN
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The crystal structure of the complex between IMP dehydrogenase catalytic domain and a transition state analogue MZP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-CARBAMOYL-1-BETA-D-RIBOFURANOSYL-IMIDAZOLIUM-5-OLATE-5'-PHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ...
著者Gan, L, Seyedsayamdost, M, Shuto, S, Matsuda, A, Petsko, G.A, Hedstrom, L.
登録日2003-06-27
公開日2003-07-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Immunosuppressive Agent Mizoribine Monophosphate Forms a Transition State Analogue Complex with Inosine Monophosphate Dehydrogenase
Biochemistry, 42, 2003
1MEH
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP and MOA bound
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ...
著者Prosise, G.L, Luecke, H.
登録日2002-08-08
公開日2003-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEI
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and mycophenolic acid bound
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, MYCOPHENOLIC ACID, POTASSIUM ION, ...
著者Prosise, G.L, Luecke, H.
登録日2002-08-08
公開日2003-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1ME9
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BU of 1me9 by Molmil
Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP bound
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, POTASSIUM ION
著者Prosise, G.L, Luecke, H.
登録日2002-08-08
公開日2003-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEW
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Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound
分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ...
著者Prosise, G.L, Luecke, H.
登録日2002-08-08
公開日2003-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1NF7
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Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
分子名称: Inosine-5'-monophosphate dehydrogenase 2, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ...
著者Risal, D, Strickler, M.D, Goldstein, B.M.
登録日2002-12-13
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structure of Human Inosine Monophosphate Dehydrogenase type II complexed with the MPA/NAD analog C2-MAD
To be Published
1NFB
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Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD
分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2, ...
著者Risal, D, Strickler, M.D, Goldstein, B.M.
登録日2002-12-13
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Conformation of NAD Bound to Human Inosine Monophosphate Dehydrogenase Type II
To be Published
2BLE
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Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP
分子名称: GMP REDUCTASE I, GUANOSINE-5'-MONOPHOSPHATE, SODIUM ION
著者Bunkoczi, G, Haroniti, A, Ng, S, von Delft, F, Oppermann, U, Arrowsmith, C, Sundstrom, M, Edwards, A, Gileadi, O.
登録日2005-03-03
公開日2005-03-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Human Guanosine Monophosphate Reductase Gmpr1 in Complex with Gmp
To be Published
1VRD
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Crystal structure of Inosine-5'-monophosphate dehydrogenase (TM1347) from THERMOTOGA MARITIMA at 2.18 A resolution
分子名称: inosine-5'-monophosphate dehydrogenase
著者Joint Center for Structural Genomics (JCSG)
登録日2005-02-22
公開日2005-03-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Crystal structure of Inosine-5'-monophosphate dehydrogenase (TM1347) from THERMOTOGA MARITIMA at 2.18 A resolution
To be published
2BWG
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Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP
分子名称: GMP REDUCTASE I, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION
著者Bunkoczi, G, Haroniti, A, Ng, S, von Delft, F, Gileadi, O, Oppermann, U, Arrowsmith, C, Edwards, A, Sundstrom, M.
登録日2005-07-13
公開日2005-07-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Human Guanosine Monophosphate Reductase Gmpr1 in Complex with Gmp
To be Published
2BZN
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Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP
分子名称: GMP REDUCTASE 2, INOSINIC ACID
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J.
登録日2005-08-19
公開日2005-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
2C6Q
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Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP and NADPH
分子名称: GMP REDUCTASE 2, INOSINIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Kursula, P, Stenmark, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J, Nordlund, P.
登録日2005-11-11
公開日2005-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
2A7R
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BU of 2a7r by Molmil
Crystal structure of human Guanosine Monophosphate reductase 2 (GMPR2)
分子名称: GMP reductase 2, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION
著者Li, J, Wei, Z, Zheng, M, Gu, X, Deng, Y, Qiu, R, Chen, F, Ji, C, Gong, W, Xie, Y, Mao, Y.
登録日2005-07-05
公開日2006-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMP
J.Mol.Biol., 355, 2006
1YPF
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Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution
分子名称: GMP reductase
著者Grenha, R, Levdikov, V.M, Blagova, E.V, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2005-01-31
公開日2006-02-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution.
To be Published
2CU0
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Crystal structure of inosine-5'-monophosphate dehydrogenase from Pyrococcus horikoshii OT3
分子名称: Inosine-5'-monophosphate dehydrogenase, XANTHOSINE-5'-MONOPHOSPHATE
著者Asada, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-24
公開日2006-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of inosine-5'-monophosphate dehydrogenase from Pyrococcus horikoshii OT3
To be Published
2A1Y
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Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.
分子名称: GMP reductase, GUANOSINE-5'-MONOPHOSPHATE
著者Grenha, R, Levdikov, V.M, Blagova, E.V, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
登録日2005-06-21
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A resolution.
To be Published

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