PDB: 26 件ウェブページステータス検索Chemie searchBIRD

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7FCY	Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor 分子名称: (1S)-2-methyl-1-(2-methyl-1,2,4-triazol-3-yl)propan-1-amine, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Tiwari, S, Pal, R.K, Biswal, B.K. 登録日 2021-07-15 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.848 Å) 主引用文献 Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor To Be Published
2F1D	X-Ray Structure of imidazoleglycerol-phosphate dehydratase 分子名称: Imidazoleglycerol-phosphate dehydratase 1, MANGANESE (II) ION, SULFATE ION 著者 Rice, D.W, Glynn, S.E, Baker, P.J, Sedelnikova, S.E, Davies, C.L, Eadsforth, T.C. 登録日 2005-11-14 公開日 2006-01-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and mechanism of imidazoleglycerol-phosphate dehydratase. Structure, 13, 2005
6YJH	Crystal structure of Imidazole Glycerol Phosphate Dehydratase from Mycobacterium tuberculosis at 1.61 A resolution 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION 著者 Timofeev, V.I, Abramchik, Y.A, Skvortsov, T.A, Azhikina, T.L, Muravieva, T.I, Kostromina, M.A, Esipov, R.S, Kuranova, I.P. 登録日 2020-04-03 公開日 2021-04-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Crystal structure of Imidazole Glycerol Phosphate Dehydratase from Mycobacterium tuberculosis at 1.61 A resolution To Be Published
2AE8	Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315 分子名称: Imidazoleglycerol-phosphate dehydratase, MAGNESIUM ION 著者 Kim, Y, Quartey, P, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2005-07-21 公開日 2005-09-06 最終更新日 2015-05-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315 To be Published
7OJ5	Cryo-EM structure of Medicago truncatula HISN5 protein 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION 著者 Ruszkowski, M, Witek, W. 登録日 2021-05-13 公開日 2021-06-02 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Cryo-EM and crystal structures of a herbicide development target, HISN5 To Be Published
4GQU	Crystal structure of HisB from Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION 著者 Ahangar, M.S, Vyas, R, Nasir, N, Biswal, B.K. 登録日 2012-08-24 公開日 2013-08-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal structures of the native, substrate- bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase Acta Crystallogr.,Sect.D, 2013
6KHH	Crystal Structure of HisB from Mycobacterium tuberculosis 分子名称: ACETAMIDE, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ... 著者 Kumar, D, Jha, B, Pal, R.K, Biswal, B.K. 登録日 2019-07-15 公開日 2020-07-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. Proteins, 2021
1RHY	Crystal structure of Imidazole Glycerol Phosphate Dehydratase 分子名称: ACETIC ACID, ETHYL MERCURY ION, GLYCEROL, ... 著者 Sinha, S.C, Chaudhuri, B.N, Burgner, J.W, Yakovleva, G, Davisson, V.J, Smith, J.L. 登録日 2003-11-14 公開日 2004-05-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of imidazole glycerol-phosphate dehydratase: duplication of an unusual fold J.Biol.Chem., 279, 2004
5XDS	Crystal structure of Mycobacterium tuberculosis HisB bound with an inhibitor 分子名称: (2S)-2-azanyl-3-(4H-1,2,4-triazol-3-yl)propanoic acid, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ... 著者 Kumar, D, Jha, B, Ahangar, M.S, Kumar, B.B. 登録日 2017-03-29 公開日 2018-04-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. Proteins, 2021
4QNJ	The structure of wt A. thaliana IGPD2 in complex with Mn2+ and formate at 1.3A resolution 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FORMIC ACID, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W. 登録日 2014-06-18 公開日 2015-06-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
4QNK	The structure of wt A. thaliana IGPD2 in complex with Mn2+ and phosphate 分子名称: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W. 登録日 2014-06-18 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
5ZQN	Crystal structure of Mycobacterium tuberculosis HisB in complex with a ligand 分子名称: (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ... 著者 Kumar, D, Pal, R.K, Biswal, B.K. 登録日 2018-04-19 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. Proteins, 2021
7DDV	Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor 分子名称: (1S)-1-(2-methyl-1,2,4-triazol-3-yl)ethanamine, CHLORIDE ION, GLYCEROL, ... 著者 Tiwari, S, Pal, R.K, Biswal, B.K. 登録日 2020-10-29 公開日 2021-11-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor To Be Published
7DNQ	Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor 分子名称: 1,2-ETHANEDIOL, 2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine, CHLORIDE ION, ... 著者 Tiwari, S, Pal, R.K, Biswal, B.K. 登録日 2020-12-10 公開日 2021-12-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor To Be Published
6EZM	Imidazoleglycerol-phosphate dehydratase from Saccharomyces cerevisiae 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid 著者 Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P. 登録日 2017-11-15 公開日 2018-02-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EZJ	Imidazoleglycerol-phosphate dehydratase 分子名称: Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, ... 著者 Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P. 登録日 2017-11-15 公開日 2018-02-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FWH	Acanthamoeba IGPD in complex with R-C348 to 1.7A resolution 分子名称: Imidazoleglycerol-phosphate dehydratase, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Roberts, C.W, Bisson, C, Baker, P.J. 登録日 2018-03-06 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials. PLoS ONE, 13, 2018
4MU4	The form B structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and its substrate, 2R3S-IGP, to 1.41 A resolution 分子名称: (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase 2, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W. 登録日 2013-09-20 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
4MU0	The structure of wt A. thaliana IGPD2 in complex with Mn2+ and 1,2,4-triazole at 1.3 A resolution 分子名称: 1,2,4-TRIAZOLE, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W. 登録日 2013-09-20 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
4MU3	The form A structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and a mixture of its substrate, 2R3S-IGP, and an inhibitor, 2S3S-IGP, to 1.12 A resolution 分子名称: (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, 1,2-ETHANEDIOL, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W. 登録日 2013-09-20 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
4MU1	The structure of wt A. thaliana IGPD2 in complex with Mn2+, imidazole, and sulfate at 1.5 A resolution 分子名称: 1,2-ETHANEDIOL, IMIDAZOLE, Imidazoleglycerol-phosphate dehydratase 2, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Baker, P.J, Rice, D.W. 登録日 2013-09-20 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure, 23, 2015
5DNL	Crystal structure of IGPD from Pyrococcus furiosus in complex with (S)-C348 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2S)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W. 登録日 2015-09-10 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55, 2016
5DNX	Crystal structure of IGPD from Pyrococcus furiosus in complex with (R)-C348 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, [(2R)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]phosphonic acid 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W. 登録日 2015-09-10 公開日 2016-10-05 最終更新日 2016-10-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55, 2016
5EKW	A. thaliana IGPD2 in complex with the racemate of the triazole-phosphonate inhibitor, C348 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W. 登録日 2015-11-04 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55, 2016
5EL9	A. thaliana IGPD2 in complex with the triazole-phosphonate inhibitor, (S)-C348, to 1.1A resolution 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Imidazoleglycerol-phosphate dehydratase 2, ... 著者 Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W. 登録日 2015-11-04 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55, 2016

 

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