PDB: 34 件ウェブページステータス検索Chemie searchBIRD

---

7RBX	Crystal structure of isocitrate lyase and phosphorylmutase:isocitrate lyase from Brucella melitensis biovar Abortus 2308 bound to itaconic acid 分子名称: 1,2-ETHANEDIOL, 2-methylidenebutanedioic acid, Isocitrase, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-07-06 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice. Plos Pathog., 17, 2021
7RB1	Isocitrate Lyase-1 from Mycobacterium tuberculosis covalently modified by 5-descarboxy-5-nitro-D-isocitric acid 分子名称: (3E)-3-(hydroxyimino)propanoic acid, GLYCEROL, GLYOXYLIC ACID, ... 著者 Krieger, I.V, Mellott, D, Meek, T, Sacchettini, J.C. 登録日 2021-07-05 公開日 2021-12-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2 R ,3 S )-2-Hydroxy-3-(nitromethyl)succinic acid. J.Am.Chem.Soc., 143, 2021
7EBC	Crystal structure of Isocitrate lyase-1 from Saccaromyces cervisiae 分子名称: Isocitrate lyase, MAGNESIUM ION, TETRAETHYLENE GLYCOL 著者 Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. 登録日 2021-03-09 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase. J.Struct.Biol., 213, 2021
7EBE	Crystal structure of Isocitrate lyase-1 from Candida albicans 分子名称: FORMIC ACID, Isocitrate lyase, MAGNESIUM ION 著者 Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. 登録日 2021-03-09 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase. J.Struct.Biol., 213, 2021
7EBF	Cryo-EM structure of Isocitrate lyase-1 from Candida albicans 分子名称: Isocitrate lyase 著者 Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. 登録日 2021-03-09 公開日 2021-06-23 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.63 Å) 主引用文献 Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase. J.Struct.Biol., 213, 2021
7CP1	Crystal structure of isocitrate lyase in complex with succinate and itaconate 分子名称: 2-methylidenebutanedioic acid, Isocitrate lyase, MAGNESIUM ION, ... 著者 Kwon, S, Park, H.H. 登録日 2020-08-05 公開日 2021-05-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism. Plos One, 16, 2021
7CMY	Isocitrate lyase from Bacillus cereus ATCC 14579 in complex with Magnessium ion, glyoxylate, and succinate 分子名称: GLYOXYLIC ACID, Isocitrate lyase, MAGNESIUM ION, ... 著者 Kim, K, Ki, D, Lee, S.H. 登録日 2020-07-29 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Isocitrate lyase from Bacillus cereus ATCC 14579 in complex with Magnessium ion, glyoxylate, and succinate To Be Published
7CMX	Isocitrate lyase from Bacillus cereus ATCC 14579 分子名称: Isocitrate lyase 著者 Kim, K, Ki, D, Lee, S.H. 登録日 2020-07-29 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Isocitrate lyase from Bacillus cereus ATCC 14579 To Be Published
6XPP	Crystal structure of itaconate modified Mycobaterium tuberculosis isocitrate lyase 分子名称: 2-methylidenebutanedioic acid, Isocitrate lyase, MAGNESIUM ION 著者 Kwai, B.X.C, Bashiri, G, Leung, I.K.H. 登録日 2020-07-08 公開日 2020-10-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Itaconate is a covalent inhibitor of the Mycobacterium tuberculosis isocitrate lyase. Rsc Med Chem, 12, 2021
6WSI	Intact cis-2,3-epoxysuccinic acid bound to Isocitrate Lyase-1 from Mycobacterium tuberculosis 分子名称: (2R,3S)-oxirane-2,3-dicarboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Krieger, I.V, Mellott, D, Meek, T.D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2020-05-01 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis -2,3-Epoxy-Succinic Acid. Acs Chem.Biol., 16, 2021
6LRP	Crystal structure of isocitrate lyase (Caur_3889) from Chloroflexus aurantiacus in complex with manganese ion 分子名称: 3,6,9,12,15-PENTAOXAHEPTADECANE, GLYCEROL, Isocitrate lyase 著者 Lee, S.H, Kim, K.J. 登録日 2020-01-16 公開日 2021-07-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural studies reveal the molecular mechanism of isocitrate lyase from Chloroflexus aurantiacus To Be Published
6LRT	Crystal structure of isocitrate lyase (Caur_3889) from Chloroflexus aurantiacus in complex with isocitrate and manganese ion 分子名称: GLYCEROL, ISOCITRIC ACID, Isocitrate lyase, ... 著者 Lee, S.H, Kim, K.J. 登録日 2020-01-16 公開日 2021-07-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural studies reveal the molecular mechanism of isocitrate lyase from Chloroflexus aurantiacus To Be Published
6VB9	Covalent adduct of cis-2,3-epoxysuccinic acid with Isocitrate Lyase-1 from Mycobacterium tuberculosis 分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, Isocitrate lyase, ... 著者 Krieger, I.V, Pham, T.V, Meek, T.D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2019-12-18 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.881 Å) 主引用文献 Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis -2,3-Epoxy-Succinic Acid. Acs Chem.Biol., 16, 2021
6EDZ	Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA, form I 分子名称: ACETYL COENZYME *A, Isocitrate lyase 2 著者 Bashiri, G, Bhusal, R, Leung, I. 登録日 2018-08-12 公開日 2019-08-14 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10, 2019
6EDW	Crystal structure of Mycobacterium tuberculosis ICL2 in the apo form 分子名称: GLYCEROL, Isocitrate lyase 2, MAGNESIUM ION 著者 Bashiri, G, Bhusal, R, Leung, I. 登録日 2018-08-12 公開日 2019-08-14 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10, 2019
6EE1	Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA 分子名称: ACETYL COENZYME *A, Isocitrate lyase 2, MAGNESIUM ION 著者 Bashiri, G, Bhusal, R, Leung, I. 登録日 2018-08-12 公開日 2019-08-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10, 2019
6G1O	Structure of Pseudomonas aeruginosa Isocitrate Lyase, ICL 分子名称: CALCIUM ION, GLYOXYLIC ACID, Isocitrate lyase 著者 Crousilles, A, Welch, M. 登録日 2018-03-21 公開日 2018-08-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.882 Å) 主引用文献 Gluconeogenic precursor availability regulates flux through the glyoxylate shunt inPseudomonas aeruginosa. J. Biol. Chem., 293, 2018
6C4A	Crystal structure of 3-nitropropionate modified isocitrate lyase from Mycobacterium tuberculosis with pyruvate 分子名称: 3-NITROPROPANOIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Kreitler, D.F, Ray, S, Murkin, A.S, Gulick, A.M. 登録日 2018-01-11 公開日 2018-06-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition. ACS Chem. Biol., 13, 2018
6C4C	Crystal structure of 3-nitropropionate modified isocitrate lyase from Mycobacterium tuberculosis with glyoxylate and pyruvate 分子名称: 3-NITROPROPANOIC ACID, GLYOXYLIC ACID, Isocitrate lyase 1, ... 著者 Kreitler, D.F, Ray, S, Murkin, A.S, Gulick, A.M. 登録日 2018-01-11 公開日 2018-06-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition. ACS Chem. Biol., 13, 2018
5E9F	Structural insights of isocitrate lyases from Magnaporthe oryzae 分子名称: Isocitrate lyase, MAGNESIUM ION 著者 Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S. 登録日 2015-10-15 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum J.Struct.Biol., 194, 2016
5E9H	Structural insights of isocitrate lyases from Fusarium graminearum 分子名称: Isocitrate lyase, MALONATE ION, MANGANESE (II) ION 著者 Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S. 登録日 2015-10-15 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum J.Struct.Biol., 194, 2016
5E9G	Structural insights of isocitrate lyases from Magnaporthe oryzae 分子名称: GLYCEROL, GLYOXYLIC ACID, Isocitrate lyase, ... 著者 Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S. 登録日 2015-10-15 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum J.Struct.Biol., 194, 2016
5DQL	Crystal Structure of 2-vinyl glyoxylate modified isocitrate lyase from Mycobacterium tuberculosis 分子名称: 4-hydroxy-2-oxobutanoic acid, Isocitrate lyase 1, MAGNESIUM ION 著者 Huang, H.-L, Meek, T.D. 登録日 2015-09-14 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3P0X	Crystal structure of isocitrate lyase from Brucella melitensis, bound to magnesium isocitrate 分子名称: 1,2-ETHANEDIOL, ISOCITRIC ACID, Isocitrate lyase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-09-29 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of isocitrate lyase from Brucella melitensis, bound to magnesium isocitrate To be Published
3OQ8	Crystal structure of isocitrate lyase from Brucella melitensis, bound to the product mimic malonate 分子名称: 1,2-ETHANEDIOL, Isocitrate lyase, MALONIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-09-02 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of isocitrate lyase from Brucella melitensis, bound to the product mimic malonate To be Published

 

12>