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5OWV
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An oligomerised bacterial dynamin pair provides a mechanism for the long-range sensing and tethering of membranes
分子名称: GTP-binding protein
著者Liu, J.W, Noel, J.K, Low, H.H.
登録日2017-09-04
公開日2018-09-05
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (3.72 Å)
主引用文献Structural basis for membrane tethering by a bacterial dynamin-like pair.
Nat Commun, 9, 2018
7ZW6
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Oligomeric structure of SynDLP
分子名称: Slr0869 protein
著者Gewehr, L, Junglas, B, Jilly, R, Franz, J, Wenyu, E.Z, Weidner, T, Bonn, M, Sachse, C, Schneider, D.
登録日2022-05-18
公開日2023-04-19
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献SynDLP is a dynamin-like protein of Synechocystis sp. PCC 6803 with eukaryotic features.
Nat Commun, 14, 2023
5OXF
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An oligomerised bacterial dynamin pair provides a mechanism for the long range sensing and tethering of membranes
分子名称: GTP-binding protein, GUANOSINE-5'-DIPHOSPHATE
著者Liu, J.W, Noel, J.K, Low, H.H.
登録日2017-09-06
公開日2018-09-05
実験手法X-RAY DIFFRACTION (3.94 Å)
主引用文献Structural basis for membrane tethering by a bacterial dynamin-like pair.
Nat Commun, 9, 2018
5YEW
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BU of 5yew by Molmil
Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion
分子名称: BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Yan, L, Qi, Y, Huang, X, Yu, C.
登録日2017-09-20
公開日2018-01-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion
Nat. Struct. Mol. Biol., 25, 2018
6J72
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BU of 6j72 by Molmil
Crystal structure of IniA from Mycobacterium smegmatis with GTP bound
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ...
著者Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
登録日2019-01-16
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
6JFK
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GDP bound Mitofusin2 (MFN2)
分子名称: CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
6J73
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Crystal structure of IniA from Mycobacterium smegmatis
分子名称: Isoniazid inducible gene protein IniA
著者Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
登録日2019-01-16
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.211 Å)
主引用文献Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
6JFL
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Nucleotide-free Mitofusin2 (MFN2)
分子名称: CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
6JFM
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Mitofusin2 (MFN2)_T111D
分子名称: ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
6JSJ
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BU of 6jsj by Molmil
Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1
分子名称: Dynamin-like GTPase MGM1, mitochondrial, GUANOSINE-5'-DIPHOSPHATE, ...
著者Yan, L, Li, L.
登録日2019-04-08
公開日2020-02-19
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1.
Proc.Natl.Acad.Sci.USA, 117, 2020
6JTG
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BU of 6jtg by Molmil
Structural insights into G domain dimerization and pathogenic mutations of OPA1
分子名称: BERYLLIUM TRIFLUORIDE ION, Dynamin-like 120 kDa protein, mitochondrial,OPA1 protein, ...
著者Yan, L, Hu, J.
登録日2019-04-11
公開日2020-04-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into G domain dimerization and pathogenic mutation of OPA1.
J.Cell Biol., 219, 2020
5GNS
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BU of 5gns by Molmil
Structures of human Mitofusin 1 provide insight into mitochondrial tethering
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Mitofusin-1
著者Qi, Y, Yan, L, Yu, C, Guo, X, Zhou, X, Hu, X, Huang, X, Rao, Z, Lou, Z, Hu, J.
登録日2016-07-24
公開日2016-12-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Structures of human Mitofusin 1 provide insight into mitochondrial tethering
To Be Published
5GOE
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BU of 5goe by Molmil
Truncated mitofusin-1, GDP-bound
分子名称: GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1
著者Cao, Y.L, Gao, S.
登録日2016-07-26
公開日2017-01-25
最終更新日2017-03-08
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
Nature, 542, 2017
5GNU
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BU of 5gnu by Molmil
the structure of mini-MFN1 apo
分子名称: Mitofusin-1
著者Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J.
登録日2016-07-25
公開日2016-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (4.113 Å)
主引用文献BDLP-like folding of Mitofusin 1
To Be Published
5GO4
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BU of 5go4 by Molmil
Truncated mitofusin-1, nucleotide-free
分子名称: Mitofusin-1
著者Cao, Y.L, Gao, S.
登録日2016-07-26
公開日2017-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
Nature, 542, 2017
5GOF
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BU of 5gof by Molmil
Truncated mitofusin-1, GTP-bound
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitofusin-1, ...
著者Cao, Y.L, Gao, S.
登録日2016-07-26
公開日2017-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
Nature, 542, 2017
5GNT
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BU of 5gnt by Molmil
BDLP-like folding of Mitofusin 1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1
著者Yan, L, Yu, C, Ming, Z, Rao, Z, Lou, Z, Hu, J.
登録日2016-07-24
公開日2016-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.665 Å)
主引用文献the structure of mini-MFN1 in complex with GDP
To Be Published
5GNR
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BU of 5gnr by Molmil
the structure of mini-MFN1 K88A in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1
著者Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Hu, J.
登録日2016-07-24
公開日2016-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献BDLP-like folding of Mitofusin 1
To Be Published
5GOM
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BU of 5gom by Molmil
Truncated mitofusin-1, transition-like state
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1
著者Cao, Y.L, Gao, S.
登録日2016-07-27
公開日2017-02-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
Nature, 542, 2017
7SOX
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BU of 7sox by Molmil
Cryo-electron tomography structure of membrane-bound EHD4 complex
分子名称: EH domain-containing protein 4
著者Melo, A.A, Noel, J.K, Daumke, O.
登録日2021-11-01
公開日2022-11-09
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Nat Commun, 13, 2022
6VJF
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BU of 6vjf by Molmil
The P-Loop K to A mutation of C. therm Vps1 GTPase-BSE
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Putative sorting protein Vps1
著者Tornabene, B.A, Varlakhanova, N.V, Chappie, J.S, Ford, M.G.J.
登録日2020-01-15
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.472 Å)
主引用文献Structural and functional characterization of the dominant negative P-loop lysine mutation in the dynamin superfamily protein Vps1.
Protein Sci., 29, 2020
6QL4
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BU of 6ql4 by Molmil
Crystal structure of nucleotide-free Mgm1
分子名称: 1,2-ETHANEDIOL, Putative mitochondrial dynamin protein
著者Faelber, K, Dietrich, L, Noel, J.K, Wollweber, F, Pfitzner, A.-K, Muehleip, A, Sanchez, R, Kudryashev, M, Chiaruttin, N, Lilie, H, Schlegel, J, Rosenbaum, E, Hessenberger, M, Matthaeus, C, Noe, F, Roux, A, vanderLaan, M, Kuehlbrandt, W, Daumke, O.
登録日2019-01-31
公開日2019-07-03
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Nature, 571, 2019
2QPT
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BU of 2qpt by Molmil
Crystal structure of an EHD ATPase involved in membrane remodelling
分子名称: CALCIUM ION, EH DOMAIN-CONTAINING PROTEIN-2, MAGNESIUM ION, ...
著者Daumke, O.
登録日2007-07-25
公開日2007-10-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Nature, 449, 2007
3L43
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BU of 3l43 by Molmil
Crystal structure of the dynamin 3 GTPase domain bound with GDP
分子名称: Dynamin-3, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
著者Yang, S, Tempel, W, Tong, Y, Nedyalkova, L, Guan, X, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2009-12-18
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of the dynamin 3 GTPase domain bound with GDP
to be published
8SKN
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BU of 8skn by Molmil
Crystal structure of compound 3-bound human Dynamin-1-like protein GTPase-BSE fusion
分子名称: 1,2-ETHANEDIOL, Dynamin-1-like protein GTPase-BSE fusion, N-[4-(azetidin-1-yl)-2-(4-methylphenyl)quinolin-6-yl]-2-methylpropanamide
著者Ma, B.
登録日2023-04-20
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Discovery of Potent Allosteric DRP1 Inhibitors by Disrupting Protein-Protein Interaction with MiD49.
Acs Med.Chem.Lett., 14, 2023

 

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