1T7H
 
 | | X-ray structure of [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide | | 分子名称: | Endothelin-1 | | 著者 | Hoh, F, Cerdan, R, Kaas, Q, Nishi, Y, Chiche, L, Kubo, S, Chino, N, Kobayashi, Y, Dumas, C, Aumelas, A. | | 登録日 | 2004-05-10 | | 公開日 | 2004-12-21 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide
Biochemistry, 43, 2004
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6DK5
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6IGK
 | | Crystal Structure of human ETB receptor in complex with Endothelin-3 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Endothelin receptor type B,Endolysin,Endothelin receptor type B, ... | | 著者 | Shihoya, W, Izume, T, Inoue, A, Yamashita, K, Kadji, F.M.N, Hirata, K, Aoki, J, Nishizawa, T, Nureki, O. | | 登録日 | 2018-09-25 | | 公開日 | 2018-11-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of human ETBreceptor provide mechanistic insight into receptor activation and partial activation.
Nat Commun, 9, 2018
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1EDN
 | | HUMAN ENDOTHELIN-1 | | 分子名称: | ENDOTHELIN-1 | | 著者 | Wallace, B.A, Janes, R.W. | | 登録日 | 1994-09-19 | | 公開日 | 1995-10-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | The crystal structure of human endothelin.
Nat.Struct.Biol., 1, 1994
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5GLH
 | | Human endothelin receptor type-B in complex with ET-1 | | 分子名称: | Endothelin Receptor Subtype-B, Peptide from Endothelin-1 | | 著者 | Shihoya, W, Nishizawa, T, Okuta, A, Tani, K, Fujiyoshi, Y, Dohmae, N, Nureki, O, Doi, T. | | 登録日 | 2016-07-11 | | 公開日 | 2016-09-07 | | 最終更新日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Activation mechanism of endothelin ETB receptor by endothelin-1.
Nature, 537, 2016
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8IY5
 | | ETB-Gi complex bound to endothelin-1 | | 分子名称: | Endothelin type B receptor, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Sano, F.K, Akasaka, H, Shihoya, W, Nureki, O. | | 登録日 | 2023-04-04 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structure of the endothelin-1-ET B -G i complex.
Elife, 12, 2023
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6LRY
 | | Crystal structure of human endothelin ETB receptor in complex with sarafotoxin S6b | | 分子名称: | Endothelin receptor type B,Endolysin,Endothelin receptor type B, Sarafotoxin-B | | 著者 | Izume, T, Miyauchi, H, Shihoya, W, Nureki, O. | | 登録日 | 2020-01-16 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human endothelin ETBreceptor in complex with sarafotoxin S6b.
Biochem.Biophys.Res.Commun., 528, 2020
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8HCQ
 | | Cryo-EM structure of endothelin1-bound ETAR-Gq complex | | 分子名称: | Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. | | 登録日 | 2022-11-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
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8IY6
 | | ETB-Gi complex bound to Endotheline-1, focused on receptor | | 分子名称: | Endothelin type B receptor, Endothelin-1 | | 著者 | Sano, F.K, Akasaka, H, Shihoya, W, Nureki, O. | | 登録日 | 2023-04-04 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Cryo-EM structure of the endothelin-1-ET B -G i complex.
Elife, 12, 2023
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8XGR
 | | ETB-eGt complex bound to endothelin-1 | | 分子名称: | Camelid antibody VHH fragment, Endothelin receptor type B, Endothelin-1, ... | | 著者 | Oshima, H.S, Sano, F.K, Akasaka, H, Iwama, A, Shihoya, W, Nureki, O. | | 登録日 | 2023-12-15 | | 公開日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Optimizing cryo-EM structural analysis of G i -coupling receptors via engineered G t and Nb35 application.
Biochem.Biophys.Res.Commun., 693, 2024
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8HCX
 | | Cryo-EM structure of Endothelin1-bound ETBR-Gq complex | | 分子名称: | Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. | | 登録日 | 2022-11-03 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
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1SRB
 | | CONFORMATIONAL STUDIES ON SRTB, A NON-SELECTIVE ENDOTHELIN RECEPTOR AGONIST, AND ON IRL 1620, AN ETB RECEPTOR SPECIFIC AGONIST | | 分子名称: | Sarafotoxins precursor | | 著者 | Smith, R, Atkins, A.R. | | 登録日 | 1994-09-06 | | 公開日 | 1994-11-01 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H NMR studies of sarafotoxin SRTb, a nonselective endothelin receptor agonist, and IRL 1620, an ETB receptor-specific agonist.
Biochemistry, 34, 1995
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1EDP
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1V6R
 | | Solution Structure of Endothelin-1 with its C-terminal Folding | | 分子名称: | Endothelin-1 | | 著者 | Takashima, H, Mimura, N, Ohkubo, T, Yoshida, T, Tamaoki, H, Kobayashi, Y. | | 登録日 | 2003-12-03 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Distributed Computing and NMR Constraint-Based High-Resolution Structure
Determination: Applied for Bioactive Peptide Endothelin-1 To Determine C-Terminal
Folding
J.Am.Chem.Soc., 126, 2004
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3CMH
 | | SYNTHETIC LINEAR TRUNCATED ENDOTHELIN-1 AGONIST | | 分子名称: | PROTEIN (ENDOTHELIN-1) | | 著者 | Hewage, C.M, Jiang, L, Parkinson, J.A, Ramage, R, Sadler, I.H. | | 登録日 | 1998-09-03 | | 公開日 | 1999-09-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling.
J.Pept.Res., 53, 1999
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6CMH
 | | SYNTHETIC LINEAR MODIFIED ENDOTHELIN-1 AGONIST | | 分子名称: | PROTEIN (ENDOTHELIN-1) | | 著者 | Hewage, C.M, Jiang, L, Parkinson, J.A, Ramage, R, Sadler, I.H. | | 登録日 | 1998-09-03 | | 公開日 | 1999-09-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling.
J.Pept.Res., 53, 1999
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2LDF
 | | Solution structure of the long sarafotoxin srtx-m | | 分子名称: | Sarafotoxin-m | | 著者 | Cordier, F, Zorba, A, Hajj, M, Ducancel, F, Servent, D, Delepierre, M. | | 登録日 | 2011-05-24 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pharmacological and structural characterization of long-sarafotoxins, a new family of endothelin-like peptides: Role of the C-terminus extension.
Biochimie, 94, 2012
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