1GP1
 
 | |
5L71
 | | Crystal structure of mouse phospholipid hydroperoxide glutathione peroxidase 4 (GPx4) | | 分子名称: | 1,2-ETHANEDIOL, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | | 著者 | Janowski, R, Scanu, S, Madl, T, Niessing, D. | | 登録日 | 2016-06-01 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta Crystallogr.,Sect.F, 72, 2016
|
|
6VPD
 | | Crystal structure of Trgpx in apo form | | 分子名称: | Glutathione peroxidase | | 著者 | Adriani, P.P, De Oliveira, G.S, Paiva, F.C.R, Dias, M.V.B, Chambergo, F.S. | | 登録日 | 2020-02-03 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | | 主引用文献 | Structural and functional characterization of the glutathione peroxidase-like thioredoxin peroxidase from the fungus Trichoderma reesei.
Int.J.Biol.Macromol., 167, 2020
|
|
6ELW
 | | High resolution structure of selenocysteine containing human GPX4 | | 分子名称: | CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | | 著者 | Kalms, J, Borchert, A, Kuhn, H, Scheerer, P. | | 登録日 | 2017-09-29 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction.
Biochim. Biophys. Acta, 1863, 2018
|
|
3KIJ
 | |
6HN3
 | | wildtype form (apo) of human GPX4 with Se-Cys46 | | 分子名称: | CHLORIDE ION, ETHANOL, GLYCEROL, ... | | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, J, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S. | | 登録日 | 2018-09-13 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
6HKQ
 | | Human GPX4 in complex with covalent Inhibitor ML162 (S enantiomer) | | 分子名称: | (2~{S})-2-[2-chloranylethanoyl-(3-chloranyl-4-methoxy-phenyl)amino]-~{N}-(2-phenylethyl)-2-thiophen-2-yl-ethanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, L, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S. | | 登録日 | 2018-09-07 | | 公開日 | 2020-04-01 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
2V1M
 | | Crystal structure of Schistosoma mansoni glutathione peroxidase | | 分子名称: | ACETATE ION, GLUTATHIONE PEROXIDASE, LITHIUM ION, ... | | 著者 | Dimastrogiovanni, D, Miele, A.E, Angelucci, F, Boumis, G, Bellelli, A, Brunori, M. | | 登録日 | 2008-09-16 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Combining Crystallography and Molecular Dynamics: The Case of Schistosoma Mansoni Phospholipid Glutathione Peroxidase.
Proteins, 78, 2010
|
|
5H5Q
 | | Crystal structure of human GPX4 in complex with GXpep-1 | | 分子名称: | GLYCEROL, GXpep-1, Phospholipid hydroperoxide glutathione peroxidase, ... | | 著者 | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
|
|
5H5R
 | | Crystal structure of human GPX4 in complex with GXpep-2 | | 分子名称: | GLYCEROL, GXpep-2, Phospholipid hydroperoxide glutathione peroxidase, ... | | 著者 | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
|
|
5H5S
 | | Crystal structure of human GPX4 in complex with GXpep-3 | | 分子名称: | GLYCEROL, GXpep-3, Phospholipid hydroperoxide glutathione peroxidase, ... | | 著者 | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
|
|
2VUP
 | |
2WGR
 | | Combining crystallography and molecular dynamics: The case of Schistosoma mansoni phospholipid glutathione peroxidase | | 分子名称: | GLUTATHIONE PEROXIDASE, PYROPHOSPHATE 2- | | 著者 | Dimastrogiovanni, D, Anselmi, M, Miele, A.E, Boumis, G, Angelucci, F, Di Nola, A, Brunori, M, Bellelli, A. | | 登録日 | 2009-04-24 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Combining Crystallography and Molecular Dynamics: The Case of Schistosoma Mansoni Phospholipid Glutathione Peroxidase.
Proteins, 78, 2010
|
|
2F8A
 | | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1 | | 分子名称: | Glutathione peroxidase 1, MALONIC ACID | | 著者 | Kavanagh, K.L, Johansson, C, Smee, C, Gileadi, O, von Delft, F, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2005-12-02 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
To be Published
|
|
2GS3
 | | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4) | | 分子名称: | CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-04-25 | | 公開日 | 2006-05-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)
To be Published
|
|
3CYN
 | | The structure of human GPX8 | | 分子名称: | GLYCEROL, Probable glutathione peroxidase 8, SULFATE ION | | 著者 | Kavanagh, K.L, Johansson, C, Yue, W.W, Kochan, G, Pike, A.C.W, Murray, J, Roos, A.K, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Wikstrom, M, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2008-04-25 | | 公開日 | 2008-08-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of human GPX8
To be Published
|
|
2HE3
 | | Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2) | | 分子名称: | CHLORIDE ION, Glutathione peroxidase 2 | | 著者 | Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-06-21 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
|
|
3CMI
 | |
2I3Y
 | | Crystal structure of human glutathione peroxidase 5 | | 分子名称: | 1,2-ETHANEDIOL, Epididymal secretory glutathione peroxidase | | 著者 | Kavanagh, K.L, Johansson, C, Rojkova, A, Umeano, C, Bunkoczi, G, Gileadi, O, von Delft, F, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-08-21 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human glutathione peroxidase 5
To be published
|
|
3E0U
 | | Crystal structure of T. cruzi GPX1 | | 分子名称: | AMMONIUM ION, GLYCEROL, Glutathione peroxidase | | 著者 | Patel, S.H, Hussain, S, Harris, R, Driscoll, P, Djordjevic, S. | | 登録日 | 2008-08-01 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I).
Biochem.J., 425, 2010
|
|
3DWV
 | |
7FC2
 | | Crystal Structure of GPX6 | | 分子名称: | Glutathione peroxidase 6, SULFATE ION | | 著者 | Sun, J. | | 登録日 | 2021-07-13 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of GPX6
To Be Published
|
|
7U4K
 | | Crystal structure of human GPX4-U46C-R152H in complex with ML162 | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-[(1R)-2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4I
 | | Crystal structure of human GPX4-U46C-R152H in complex with CDS9 | | 分子名称: | 2-bromo-N-[(thiophen-2-yl)methyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4N
 | | Crystal structure of human GPX4-U46C in complex with RSL3 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
