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1E17
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Solution structure of the DNA binding domain of the human Forkhead transcription factor AFX (FOXO4)
分子名称: AFX
著者Weigelt, J, Climent, I, Dahlman-Wright, K, Wikstrom, M.
登録日2000-04-25
公開日2000-08-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N Resonance Assignments of the DNA Binding Domain of the Human Forkhead Transcription Factor Afx
J.Biomol.NMR, 17, 2000
1D5V
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BU of 1d5v by Molmil
SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12)
分子名称: S12 TRANSCRIPTION FACTOR (FKH-14)
著者van Dongen, M.J.P, Cederberg, A, Carlsson, P, Enerback, S, Wikstrom, M.
登録日1999-10-12
公開日2000-10-11
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11.
J.Mol.Biol., 296, 2000
7FJ2
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Structure of FOXM1 homodimer bound to a palindromic DNA site
分子名称: DNA (5'-D(*AP*CP*CP*GP*TP*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*AP*CP*GP*GP*T)-3'), Forkhead box protein M1
著者Dai, S.Y, Li, J, Zhang, H.J.
登録日2021-08-02
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.098 Å)
主引用文献Mechanistic Insights into the Preference for Tandem Binding Sites in DNA Recognition by FOXM1.
J.Mol.Biol., 434, 2021
6XAT
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Crystal structure of the human FoxP4 DNA binding Domain
分子名称: FOXP4 protein, SODIUM ION
著者VIllalobos, P, Castro-Fernandez, V, Medina, E, Gonzalez-Ordenes, F, Maturana, P, Herrera-Morande, A, Ramirez-Sarmiento, C.A, Babul, J.
登録日2020-06-04
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unraveling the folding and dimerization properties of the human FoxP subfamily of transcription factors.
Febs Lett., 597, 2023
6EL8
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BU of 6el8 by Molmil
Crystal structure of the Forkhead domain of human FOXN1 in complex with DNA
分子名称: DNA (5'-D(*GP*GP*TP*GP*GP*CP*GP*TP*CP*TP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*AP*GP*AP*CP*GP*CP*CP*AP*CP*C)-3'), Forkhead box protein N1
著者Newman, J.A, Aitkenhead, H.A, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC)
登録日2017-09-28
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Crystal structure of the Forkhead domain of human FOXN1 in complex with DNA
To be published
5DUI
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Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter
分子名称: DNA (5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'), Forkhead box protein O1
著者Singh, P, Endrizzi, J.A, Chi, Y.-I.
登録日2015-09-18
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter.
J. Struct. Biol., 198, 2017
4WK8
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FOXP3 forms a domain-swapped dimer to bridge DNA
分子名称: DNA (5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3'), Forkhead box protein P3
著者Chen, Y, Chen, L.
登録日2014-10-01
公開日2015-01-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.4006 Å)
主引用文献DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Nucleic Acids Res., 43, 2015
6QVW
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Solution structure of the free FOXO1 DNA binding domain
分子名称: Forkhead box protein O1
著者Psenakova, K, Obsil, T, Veverka, V, Obsilova, V, Kohoutova, K.
登録日2019-03-05
公開日2019-09-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics.
Cells, 8, 2019
1VTN
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CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITION MOTIF RESEMBLES HISTONE H5
分子名称: DNA (5'-D(*GP*AP*CP*TP*AP*AP*GP*TP*CP*AP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*GP*AP*CP*TP*TP*AP*GP*TP*C)-3'), HNF-3/FORK HEAD DNA-RECOGNITION MOTIF, ...
著者Clark, K.L, Halay, E.D, Lai, E, Burley, S.K.
登録日1995-01-06
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Co-Crystal Structure of the HNF-3/Fork Head DNA-Recognition Motif Resembles Histone H5
Nature, 364, 1993
7CBY
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Structure of FOXG1 DNA binding domain bound to DBE2 DNA site
分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), ...
著者Dai, S.Y, Li, J, Chen, Y.H.
登録日2020-06-15
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.646 Å)
主引用文献Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations.
J.Mol.Biol., 432, 2020
5OCN
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Crystal structure of the forkhead domain of human FOXN1
分子名称: Forkhead box protein N1, POTASSIUM ION
著者Newman, J.A, Aitkenhead, H, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Edwwards, A, Bountra, C, Gileadi, O.
登録日2017-07-03
公開日2017-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the forkhead domain of human FOXN1
To be published
5X07
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BU of 5x07 by Molmil
Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site
分子名称: DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta
著者Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y.
登録日2017-01-20
公開日2017-08-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site
Biochemistry, 56, 2017
3L2C
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BU of 3l2c by Molmil
Crystal Structure of the DNA Binding Domain of FOXO4 Bound to DNA
分子名称: FOXO consensus binding sequence, minus strand, plus strand, ...
著者Boura, E, Silhan, J, Sulc, M, Brynda, J, Obsilova, V, Obsil, T.
登録日2009-12-15
公開日2009-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献Structure of the human FOXO4-DBD-DNA complex at 1.9 A resolution reveals new details of FOXO binding to the DNA
Acta Crystallogr.,Sect.D, 66, 2010
2UZK
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Crystal structure of the human FOXO3a-DBD bound to DNA
分子名称: 5'-D(*CP*TP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*AP*G)-3', FORKHEAD BOX PROTEIN O3A
著者Tsai, K.-L, Sun, Y.-J, Huang, C.-Y, Yang, J.-Y, Hung, M.-C, Hsiao, C.-D.
登録日2007-04-30
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the Human Foxo3A-Dbd/DNA Complex Suggests the Effects of Post-Translational Modification.
Nucleic Acids Res., 35, 2007
1JXS
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Solution Structure of the DNA-Binding Domain of Interleukin Enhancer Binding Factor
分子名称: interleukin enhancer binding factor
著者Chuang, W.J, Liu, P.P, Li, C, Hsieh, Y.H, Chen, S.W, Chen, S.H, Jeng, W.Y.
登録日2001-09-08
公開日2003-03-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a)
PROTEINS: STRUCT.,FUNCT.,GENET., 49, 2002
6AKO
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BU of 6ako by Molmil
Crystal Structure of FOXC2 DBD Bound to DBE2 DNA
分子名称: DNA (5'-D(CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Forkhead box protein C2, ...
著者Chen, X, Wei, H, Li, J, Liang, X, Dai, S, Jiang, L, Guo, M, Chen, Y.
登録日2018-09-03
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献Structural basis for DNA recognition by FOXC2.
Nucleic Acids Res., 47, 2019
6AKP
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Crystal Structural of FOXC2 DNA binding domain bound to PC promoter
分子名称: DNA (5'-D(AP*CP*AP*CP*AP*AP*AP*TP*AP*TP*TP*TP*GP*TP*GP*T)-3'), Forkhead box protein C2, MAGNESIUM ION
著者Chen, X, Wei, H, Li, J, Liang, X, Dai, S, Jiang, L, Guo, M, Chen, Y.
登録日2018-09-03
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.323 Å)
主引用文献Structural basis for DNA recognition by FOXC2.
Nucleic Acids Res., 47, 2019
1KQ8
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BU of 1kq8 by Molmil
Solution Structure of Winged Helix Protein HFH-1
分子名称: HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1
著者Sheng, W, Rance, M, Liao, X.
登録日2002-01-04
公開日2002-01-22
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structure comparison of two conserved HNF-3/fkh proteins HFH-1 and genesis indicates the existence of folding differences in their complexes with a DNA binding sequence.
Biochemistry, 41, 2002
6LBM
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Crystal Structure of FOXC2-DBD bound to a palindromic DNA sequence
分子名称: Forkhead box protein C2, IRE0, MAGNESIUM ION
著者Li, J, Dai, S.Y.
登録日2019-11-14
公開日2021-02-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.841 Å)
主引用文献Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
Nucleic Acids Res., 49, 2021
6LBI
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Crystal Structure of FOXO1-DBD homodimer bound to a palindromic DNA sequence
分子名称: Forkhead box protein O1, IRE0
著者Li, J, Dai, S.Y, Chen, Y.H.
登録日2019-11-14
公開日2021-02-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.067 Å)
主引用文献Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
Nucleic Acids Res., 49, 2021
6NCM
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BU of 6ncm by Molmil
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence
分子名称: DNA (5'-D(*AP*TP*AP*GP*CP*GP*TP*CP*TP*TP*AP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*CP*TP*AP*AP*GP*AP*CP*GP*CP*TP*A)-3'), Forkhead box protein N3, ...
著者Rogers, J.M, Jarrett, S.M, Seegar, T.C, Waters, C.T, Hallworth, A.N, Blacklow, S.C, Bulyk, M.L.
登録日2018-12-11
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.
Mol. Cell, 74, 2019
6NCE
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Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence
分子名称: DNA (5'-D(*AP*CP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*TP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*TP*AP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), Forkhead box protein N3, ...
著者Rogers, J.M, Jarrett, S.M, Seegar, T.C, Waters, C.T, Hallworth, A.N, Blacklow, S.C, Bulyk, M.L.
登録日2018-12-11
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.
Mol. Cell, 74, 2019
6O3T
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Structural basis of FOXC2 and DNA interactions
分子名称: DNA (5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein C2
著者Nam, H.-J, Li, S.
登録日2019-02-27
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Crystal Structure of FOXC2 in Complex with DNA Target.
Acs Omega, 4, 2019
2HDC
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STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX
分子名称: DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3'), PROTEIN (TRANSCRIPTION FACTOR)
著者Jin, C, Marsden, I, Chen, X, Liao, X.
登録日1999-05-05
公開日1999-07-05
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex.
J.Mol.Biol., 289, 1999
2HFH
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THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES
分子名称: GENESIS
著者Marsden, I, Jin, C, Liao, X.
登録日1998-01-27
公開日1998-06-17
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins.
J.Mol.Biol., 278, 1998

 

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