PDB: 253 件ウェブページステータス検索Chemie searchBIRD

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1BG2	HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, KINESIN, ... 著者 Kull, F.J, Sablin, E.P, Lau, R, Fletterick, R.J, Vale, R.D. 登録日 1998-06-04 公開日 1998-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature, 380, 1996
1CZ7	THE CRYSTAL STRUCTURE OF A MINUS-END DIRECTED MICROTUBULE MOTOR PROTEIN NCD REVEALS VARIABLE DIMER CONFORMATIONS 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MICROTUBULE MOTOR PROTEIN NCD 著者 Kozielski, F.K, De Bonis, S, Burmeister, W, Cohen-Addad, C, Wade, R. 登録日 1999-09-01 公開日 1999-11-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations. Structure Fold.Des., 7, 1999
1F9T	CRYSTAL STRUCTURES OF KINESIN MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.-G, Park, H.-W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
1F9U	CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
1F9V	CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
1F9W	CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION 著者 Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. 登録日 2000-07-11 公開日 2001-06-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A structural pathway for activation of the kinesin motor ATPase. EMBO J., 20, 2001
1GOJ	Structure of a fast kinesin: Implications for ATPase mechanism and interactions with microtubules 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION 著者 Song, Y.-H, Marx, A, Muller, J, Woehlke, G, Schliwa, M, Krebs, A, Hoenger, A, Mandelkow, E. 登録日 2001-10-21 公開日 2001-11-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a Fast Kinesin: Implications for ATPase Mechanism and Interactions with Microtubules Embo J., 20, 2001
1I5S	CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION 著者 Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. 登録日 2001-02-28 公開日 2001-05-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Switch-based mechanism of kinesin motors Nature, 411, 2001
1I6I	CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION, ... 著者 Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. 登録日 2001-03-02 公開日 2001-05-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Switch-based mechanism of kinesin motors Nature, 411, 2001
1IA0	KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ... 著者 Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. 登録日 2001-03-22 公開日 2002-03-22 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Switch-based Mechanism of Kinesin Motors Nature, 411, 2001
1II6	Crystal Structure of the Mitotic Kinesin Eg5 in Complex with Mg-ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-RELATED MOTOR PROTEIN Eg5, MAGNESIUM ION, ... 著者 Turner, J, Anderson, R, Guo, J, Beraud, C, Sakowicz, R, Fletterick, R. 登録日 2001-04-20 公開日 2001-07-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker. J.Biol.Chem., 276, 2001
1MKJ	Human Kinesin Motor Domain With Docked Neck Linker 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ... 著者 Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R. 登録日 2002-08-29 公開日 2002-10-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy. Nat.Struct.Biol., 9, 2002
1N6M	Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd 分子名称: ADENOSINE-5'-DIPHOSPHATE, Claret segregational protein, MAGNESIUM ION 著者 Yun, M, Bronner, C.E, Park, C.-G, Cha, S.-S, Park, H.-W, Endow, S.A. 登録日 2002-11-11 公開日 2003-10-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd EMBO J., 22, 2003
1Q0B	Crystal structure of the motor protein KSP in complex with ADP and monastrol 分子名称: ADENOSINE-5'-DIPHOSPHATE, ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE, Kinesin-like protein KIF11, ... 著者 Yan, Y, Sardana, V, Xu, B, Halczenko, W, Homnick, C, Buser, C.A, Hartman, G.D, Huber, H.E, Kuo, L.C. 登録日 2003-07-15 公開日 2004-01-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Inhibition of a mitotic motor protein: where, how, and conformational consequences J.Mol.Biol., 335, 2004
1RY6	Crystal Structure of Internal Kinesin Motor Domain 分子名称: INTERNAL KINESIN, SULFATE ION 著者 Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R. 登録日 2003-12-19 公開日 2004-04-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of a kinesin microtubule depolymerization machine. Embo J., 23, 2004
1SDM	Crystal structure of kinesin-like calmodulin binding protein 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kinesin heavy chain-like protein 著者 Vinogradova, M.V, Reddy, V.S, Reddy, A.S, Sablin, E.P, Fletterick, R.J. 登録日 2004-02-13 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of kinesin regulated by Ca(2+)-calmodulin. J.Biol.Chem., 279, 2004
1T5C	Crystal structure of the motor domain of human kinetochore protein CENP-E 分子名称: ADENOSINE-5'-DIPHOSPHATE, Centromeric protein E, MAGNESIUM ION, ... 著者 Garcia-Saez, I, Yen, T, Wade, R.H, Kozielski, F, Structural Proteomics in Europe (SPINE) 登録日 2004-05-04 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the motor domain of the human kinetochore protein CENP-E. J.Mol.Biol., 340, 2004
1V8J	The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION 著者 Ogawa, T, Nitta, R, Okada, Y, Hirokawa, N. 登録日 2004-01-09 公開日 2004-03-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell(Cambridge,Mass.), 116, 2004
1V8K	The Crystal Structure of the Minimal Functional Domain of the Microtubule Destabilizer KIF2C Complexed with Mg-AMPPNP 分子名称: Kinesin-like protein KIF2C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Ogawa, T, Nitta, R, Okada, Y, Hirokawa, N. 登録日 2004-01-09 公開日 2004-03-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell(Cambridge,Mass.), 116, 2004
1VFV	Crystal Structure of the Kif1A Motor Domain Complexed With Mg-AMPPNP 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1VFW	Crystal Structure of the Kif1A Motor Domain Complexed With Mg-AMPPNP 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1VFX	Crystal Structure of the Kif1A Motor Domain Complexed With ADP-Mg-AlFx 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1VFZ	Crystal Structure of the Kif1A Motor Domain Complexed With ADP-Mg-VO4 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (Fusion protein consisting of Kinesin-like protein KIF1A, ... 著者 Nitta, R, Kikkawa, M, Okada, Y, Hirokawa, N. 登録日 2004-04-19 公開日 2004-08-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 KIF1A Alternately Uses Two Loops to Bind Microtubules Science, 305, 2004
1X88	Human Eg5 motor domain bound to Mg-ADP and monastrol 分子名称: ADENOSINE-5'-DIPHOSPHATE, ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE, Kinesin-like protein KIF11, ... 著者 Maliga, Z, Mitchison, T.J. 登録日 2004-08-17 公開日 2005-11-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of Eg5 Inhibition by Monastrol TO BE PUBLISHED
1YRS	Crystal structure of KSP in complex with inhibitor 1 分子名称: 3-[(5S)-1-ACETYL-3-(2-CHLOROPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-5-YL]PHENOL, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... 著者 Cox, C.D, Breslin, M.J, Mariano, B.J, Coleman, P.J, Buser, C.A, Walsh, E.S, Hamilton, K, Kohl, N.E, Torrent, M, Yan, Y, Kuo, L.C, Hartman, G.D. 登録日 2005-02-04 公開日 2005-04-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP BIOORG.MED.CHEM.LETT., 15, 2005

 

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