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5NNN
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Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like
分子名称: GLYCEROL, ctATC
著者Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
7AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ...
著者Gouaux, J.E, Stevens, R.C, Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
9ATC
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ATCASE Y165F MUTANT
分子名称: ASPARTATE TRANSCARBAMOYLASE, ZINC ION
著者Ha, Y, Allewell, N.M.
登録日1998-06-26
公開日1999-07-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intersubunit hydrogen bond acts as a global molecular switch in Escherichia coli aspartate transcarbamoylase.
Proteins, 33, 1998
5AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
7TMD
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Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae
分子名称: BROMIDE ION, IODIDE ION, Ornithine carbamoyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-01-19
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae
To be published
1C9Y
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HUMAN ORNITHINE TRANSCARBAMYLASE: CRYSTALLOGRAPHIC INSIGHTS INTO SUBSTRATE RECOGNITION AND CATALYTIC MECHANISM
分子名称: NORVALINE, ORNITHINE CARBAMOYLTRANSFERASE, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
著者Shi, D, Yu, X, Morizono, H, Tuchman, M, Allewell, N.M.
登録日1999-08-03
公開日2000-06-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution.
Proteins, 39, 2000
2W37
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CRYSTAL STRUCTURE OF THE HEXAMERIC CATABOLIC ORNITHINE TRANSCARBAMYLASE FROM Lactobacillus hilgardii
分子名称: NICKEL (II) ION, ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC
著者de las Rivas, B, Fox, G.C, Angulo, I, Rodriguez, H, Munoz, R, Mancheno, J.M.
登録日2008-11-06
公開日2009-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Hexameric Catabolic Ornithine Transcarbamylase from Lactobacillus Hilgardii: Structural Insights Into the Oligomeric Assembly and Metal Binding.
J.Mol.Biol., 393, 2009
6FBA
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Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2,3-naphthalenediol
分子名称: Aspartate transcarbamoylase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
著者Lunev, S, Bosch, S.S, Batista, F.A, Wang, C, Wrenger, C, Groves, M.R.
登録日2017-12-18
公開日2018-02-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem. Biophys. Res. Commun., 497, 2018
7K46
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Crystal Structure of a putative aspartate carbamoyltransferase Leishmania major Friedlin
分子名称: 1,2-ETHANEDIOL, Aspartate carbamoyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-14
公開日2020-09-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of a putative aspartate carbamoyltransferase Leishmania major Friedlin
to be published
5VMQ
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STRUCTURE OF THE R105A MUTANT CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE AT 2.0-A RESOLUTION
分子名称: Aspartate carbamoyltransferase, CALCIUM ION, CHLORIDE ION
著者Beernink, P.T, Endrizzi, J.A.
登録日2017-04-28
公開日2017-05-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Charge neutralization in the active site of the catalytic trimer of aspartate transcarbamoylase promotes diverse structural changes.
Protein Sci., 26, 2017
5NNQ
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Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
分子名称: GLYCEROL, ctATC
著者Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
6AT1
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BU of 6at1 by Molmil
STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
8BPL
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BU of 8bpl by Molmil
Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2022-11-16
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
8BPS
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BU of 8bps by Molmil
Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like in apo form
分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2022-11-25
公開日2023-02-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
6OVW
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Crystal structure of ornithine carbamoyltransferase from Salmonella enterica
分子名称: GLYCEROL, Ornithine carbamoyltransferase, PHOSPHATE ION
著者Chang, C, Mesa, N, Skarina, T, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-05-08
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structure of ornithine carbamoyltransferase from Salmonella enterica
To Be Published
6PNZ
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The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
分子名称: Aspartate carbamoyltransferase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Edwards, B.F.P, Evans, D.R, Patel, C.
登録日2019-07-03
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
To Be Published
8QEV
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BU of 8qev by Molmil
Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with carbamoyl phosphate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ornithine transcarbamylase, ...
著者Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B.
登録日2023-09-01
公開日2023-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae .
Front Plant Sci, 14, 2023
8QEU
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BU of 8qeu by Molmil
Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with ornithine
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-ornithine, ...
著者Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B.
登録日2023-09-01
公開日2023-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae .
Front Plant Sci, 14, 2023
4KWT
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BU of 4kwt by Molmil
Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Ornithine carbamoyltransferase
著者Shabalin, I.G, Bacal, P, Bajor, J, Winsor, J, Grimshaw, S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-05-24
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
To be Published
1I5O
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BU of 1i5o by Molmil
CRYSTAL STRUCTURE OF MUTANT R105A OF E. COLI ASPARTATE TRANSCARBAMOYLASE
分子名称: ASPARTATE TRANSCARBAMOYLASE CATALYTIC CHAIN, ASPARTATE TRANSCARBAMOYLASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ...
著者Macol, C.P, Tsuruta, H, Stec, B, Kantrowitz, E.R.
登録日2001-02-28
公開日2001-05-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Direct structural evidence for a concerted allosteric transition in Escherichia coli aspartate transcarbamoylase.
Nat.Struct.Biol., 8, 2001
1JS1
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Crystal Structure of a new transcarbamylase from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution
分子名称: PHOSPHATE ION, Transcarbamylase
著者Shi, D, Gallegos, R, DePonte III, J, Morizono, H, Yu, X, Allewell, N.M, Malamy, M, Tuchman, M.
登録日2001-08-15
公開日2002-07-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution.
J.Mol.Biol., 320, 2002
4NF2
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BU of 4nf2 by Molmil
Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline
分子名称: CHLORIDE ION, NORVALINE, Ornithine carbamoyltransferase, ...
著者Shabalin, I.G, Handing, K, Cymborowski, M.T, Stam, J, Winsor, J, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-10-30
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
To be Published
4OH7
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Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ornithine carbamoyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-01-17
公開日2014-02-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
To be Published
1ML4
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The PALA-liganded Aspartate transcarbamoylase catalytic subunit from Pyrococcus abyssi
分子名称: Aspartate Transcarbamoylase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Van Boxstael, S, Cunin, R, Maes, D.
登録日2002-08-30
公開日2003-02-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Aspartate Transcarbamylase from the Hyperthermophilic Archaeon Pyrococcus abyssi: Thermostability and 1.8A Resolution Crystal Structure of the Catalytic Subunit Complexed With the Bisubstrate Analogue N-Phosphonacetyl-L-aspartate.
J.Mol.Biol., 326, 2003
5G1N
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Aspartate transcarbamoylase domain of human CAD bound to PALA
分子名称: 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016

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