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6UXZ
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(S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR
分子名称: (4S)-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-5-phenoxypentanoic acid, HTH-type transcriptional regulatory protein GabR, SULFATE ION
著者Catlin, D.S, Liu, D.
登録日2019-11-09
公開日2020-10-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献(S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR.
Protein Sci., 29, 2020
6ONN
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BU of 6onn by Molmil
Crystal structure of 8-amino-7-oxononanoate synthase from Burkholderia phymatum
分子名称: 8-amino-7-oxononanoate synthase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-04-22
公開日2019-05-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of 8-amino-7-oxononanoate synthase from Burkholderia phymatum
To be published
7N79
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BU of 7n79 by Molmil
O2-, PLP-dependent desaturase Plu4 holo-enzyme
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ...
著者Hoffarth, E.R, Ryan, K.S.
登録日2021-06-09
公開日2021-10-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases.
Proc.Natl.Acad.Sci.USA, 118, 2021
5JAY
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BU of 5jay by Molmil
Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans
分子名称: 8-amino-7-oxononanoate synthase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2016-04-12
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans
to be published
2G6W
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BU of 2g6w by Molmil
Suicide inhibition of a-Oxamine Synthase: Structures of the Covalent Adducts of 8-Amino-7-oxonanoate Synthase with trifluoroalanine
分子名称: (4-{(E)-[(2,2-DIFLUOROETHYL)IMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 8-amino-7-oxononanoate synthase
著者Alexeev, D.
登録日2006-02-26
公開日2006-04-25
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine.
Org.Biomol.Chem., 4, 2006
2GB3
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BU of 2gb3 by Molmil
Crystal structure of Aspartate aminotransferase (tm1698) from Thermotoga maritima at 2.50 A resolution
分子名称: aspartate aminotransferase
著者Joint Center for Structural Genomics (JCSG)
登録日2006-03-09
公開日2006-03-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Aspartate aminotransferase (tm1698) from Thermotoga maritima at 2.50 A resolution
To be published
7AAT
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BU of 7aat by Molmil
X-RAY STRUCTURE REFINEMENT AND COMPARISON OF THREE FORMS OF MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE
分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Mcphalen, C.A, Vincent, M.G, Jansonius, J.N.
登録日1991-12-02
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase.
J.Mol.Biol., 225, 1992
6ZUP
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BU of 6zup by Molmil
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-(-)-3-phenyllactic acid
分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, Aminotransferase, MAGNESIUM ION, ...
著者Bujacz, A, Rum, J, Rutkiewicz, M, Pietrzyk-Brzezinska, A.J, Bujacz, G.
登録日2020-07-23
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6.
Materials (Basel), 14, 2021
6ZVG
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BU of 6zvg by Molmil
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-indole-3-lactic acid
分子名称: 3-(INDOL-3-YL) LACTATE, Aminotransferase, MAGNESIUM ION, ...
著者Rum, J, Rutkiewicz, M, Pruska, A, Bujacz, A, Pietrzyk-Brzezinska, A.J, Bujacz, G.
登録日2020-07-24
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6.
Materials (Basel), 14, 2021
6ZUR
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Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - L-p-hydroxyphenyllactic acid
分子名称: (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid, Aminotransferase, MAGNESIUM ION, ...
著者Bujacz, A, Rum, J, Rutkiewicz, M, Pietrzyk-Brzezinska, A.J, Bujacz, G.
登録日2020-07-23
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6.
Materials (Basel), 14, 2021
2JG2
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BU of 2jg2 by Molmil
HIGH RESOLUTION STRUCTURE OF SPT WITH PLP INTERNAL ALDIMINE
分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J.
登録日2007-02-07
公開日2007-05-01
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis.
J.Mol.Biol., 370, 2007
5BJ3
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BU of 5bj3 by Molmil
THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 1
分子名称: PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE
著者Ura, H, Nakai, T, Kawaguchi, S.I, Miyahara, I, Hirotsu, K, Kuramitsu, S.
登録日1999-01-11
公開日2003-09-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate recognition mechanism of thermophilic dual-substrate enzyme
J.BIOCHEM.(TOKYO), 130, 2001
5AX8
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BU of 5ax8 by Molmil
Recombinant expression, purification and preliminary crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
分子名称: Aspartate aminotransferase, mitochondrial
著者Jiang, X, Wang, J, Chang, H, Zhou, Y.
登録日2015-07-20
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
Biosci Trends, 10, 2016
5BK7
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BU of 5bk7 by Molmil
The structure of MppP E15A mutant soaked with the substrate L-arginine
分子名称: (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, PLP-Dependent L-Arginine Hydroxylase MppP
著者Han, L, Silvaggi, N.R.
登録日2018-01-27
公開日2018-09-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Streptomyces wadayamensis MppP is a PLP-Dependent Oxidase, Not an Oxygenase.
Biochemistry, 57, 2018
2JGT
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BU of 2jgt by Molmil
Low resolution structure of SPT
分子名称: SERINE PALMITOYLTRANSFERASE
著者Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J.
登録日2007-02-14
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis.
J.Mol.Biol., 370, 2007
5BJ4
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BU of 5bj4 by Molmil
THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2
分子名称: PHOSPHATE ION, PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE
著者Ura, H, Nakai, T, Kawaguchi, S.I, Miyahara, I, Hirotsu, K, Kuramitsu, S.
登録日1999-01-11
公開日2003-09-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Substrate recognition mechanism of thermophilic dual-substrate enzyme
J.BIOCHEM.(TOKYO), 130, 2001
4W5K
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BU of 4w5k by Molmil
Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei, K237A mutant
分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase, mitochondrial, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-08-18
公開日2014-09-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.
Acta Crystallogr.,Sect.F, 71, 2015
4R5Z
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BU of 4r5z by Molmil
Crystal structure of Rv3772 encoded aminotransferase
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者Nasir, N, Anant, A, Vyas, R, Biswal, B.K.
登録日2014-08-22
公開日2015-08-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities
Sci Rep, 6, 2016
5DJ3
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BU of 5dj3 by Molmil
Structure of the PLP-Dependent L-Arginine Hydroxylase MppP with D-Arginine Bound
分子名称: (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-D-arginine, MAGNESIUM ION, PLP-Dependent L-Arginine Hydroxylase MppP
著者Silvaggi, N.R, Han, L.
登録日2015-09-01
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.227 Å)
主引用文献Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent l-Arginine alpha-Deaminase, gamma-Hydroxylase in the Enduracididine Biosynthetic Pathway.
Biochemistry, 54, 2015
5DJ1
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Structure of the PLP-Dependent L-Arginine Hydroxylase MppP Holoenzyme
分子名称: CHLORIDE ION, MAGNESIUM ION, PLP-Dependent L-Arginine Hydroxylase MppP
著者Silvaggi, N.R, Han, L.
登録日2015-09-01
公開日2015-11-25
最終更新日2017-05-03
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent l-Arginine alpha-Deaminase, gamma-Hydroxylase in the Enduracididine Biosynthetic Pathway.
Biochemistry, 54, 2015
6QP3
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Crystal structure of the PLP-bound C-S lyase from Bacillus subtilis (strain 168)
分子名称: ACETATE ION, Cystathionine beta-lyase PatB, PYRIDOXAL-5'-PHOSPHATE
著者Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H.
登録日2019-02-13
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The molecular basis of thioalcohol production in human body odour.
Sci Rep, 10, 2020
4WBT
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BU of 4wbt by Molmil
Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Shabalin, I.G, Bacal, P, Kowalska, A.K, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-09-03
公開日2014-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
to be published
4RKD
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BU of 4rkd by Molmil
Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with aspartic acid
分子名称: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aromatic amino acid aminotransferase, ...
著者Bujacz, A, Rutkiewicz-Krotewicz, M, Bujacz, G, Nowakowska-Sapota, K, Turkiewicz, M.
登録日2014-10-12
公開日2015-03-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Crystal structure and enzymatic properties of a broad substrate-specificity psychrophilic aminotransferase from the Antarctic soil bacterium Psychrobacter sp. B6.
Acta Crystallogr.,Sect.D, 71, 2015
4WP0
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Crystal structure of human kynurenine aminotransferase-I with a C-terminal V5-hexahistidine tag
分子名称: Kynurenine--oxoglutarate transaminase 1
著者Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B.
登録日2014-10-17
公開日2014-11-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human kynurenine aminotransferase-I in a novel space group
To be published
4WLJ
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High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate
分子名称: 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Kynurenine--oxoglutarate transaminase 1
著者Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B.
登録日2014-10-07
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate.
Protein Sci., 26, 2017

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