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3REU
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BU of 3reu by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid and Adenosine triphosphate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein, ...
著者Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
登録日2011-04-05
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
1NNH
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BU of 1nnh by Molmil
Hypothetical protein from Pyrococcus furiosus Pfu-1801964
分子名称: SODIUM ION, asparaginyl-tRNA synthetase-related peptide
著者Tempel, W, Liu, Z.-J, Schubot, F.D, Shah, A, Arendall III, W.B, Rose, J.P, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-01-13
公開日2004-02-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Hypothetical protein from Pyrococcus furiosus Pfu-1801964
To be published
3G1Z
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BU of 3g1z by Molmil
Structure of IDP01693/yjeA, a potential t-RNA synthetase from Salmonella typhimurium
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PHOSPHATE ION, ...
著者Singer, A.U, Evdokimova, E, Kudritska, M, Cuff, M.E, Edwards, A.M, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-01-30
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica.
Mol.Cell, 39, 2010
3A5Y
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BU of 3a5y by Molmil
Crystal structure of GenX from Escherichia coli in complex with lysyladenylate analog
分子名称: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Putative lysyl-tRNA synthetase
著者Sumida, T, Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2009-08-17
公開日2010-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P.
Nat.Struct.Mol.Biol., 17, 2010
3P8Y
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BU of 3p8y by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine
分子名称: ASPARAGINE, AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3P8T
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BU of 3p8t by Molmil
Crystal structure of the archaeal asparagine synthetase A
分子名称: AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3P8V
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BU of 3p8v by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid
分子名称: ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3REX
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BU of 3rex by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with Adenosine monophosphate
分子名称: ADENOSINE MONOPHOSPHATE, AsnS-like asparaginyl-tRNA synthetase related protein, MAGNESIUM ION
著者Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
登録日2011-04-05
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3RL6
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BU of 3rl6 by Molmil
Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine and Adenosine monophosphate
分子名称: ADENOSINE MONOPHOSPHATE, ASPARAGINE, Archaeal asparagine synthetase A, ...
著者Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
登録日2011-04-19
公開日2011-08-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
8H53
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BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
分子名称: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
著者Park, J.S, Han, B.W.
登録日2022-10-12
公開日2023-10-25
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
To Be Published
4WJ3
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BU of 4wj3 by Molmil
Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa
分子名称: 76mer-tRNA, Aspartate--tRNA(Asp/Asn) ligase, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, ...
著者Suzuki, T, Nakamura, A, Kato, K, Tanaka, I, Yao, M.
登録日2014-09-29
公開日2014-12-31
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (3.705 Å)
主引用文献Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis
Proc.Natl.Acad.Sci.USA, 112, 2015
6WOM
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BU of 6wom by Molmil
Crystal structure of Aspartyl-tRNA ligase from Elizabethkingia sp.
分子名称: Aspartate--tRNA ligase, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-04-24
公開日2020-05-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of Aspartyl-tRNA ligase from Elizabethkingia sp.
TO BE PUBLISHED
1B8A
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BU of 1b8a by Molmil
ASPARTYL-TRNA SYNTHETASE
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROTEIN (ASPARTYL-TRNA SYNTHETASE)
著者Schmitt, E, Moulinier, L, Thierry, J.-C, Moras, D.
登録日1999-01-27
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation.
EMBO J., 17, 1998
7ZOG
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BU of 7zog by Molmil
Crystal structure of Cryptosporidium parvum -Plasmodium falciparum mutant lysyl tRNA synthetase in complex with inhibitor
分子名称: 8-[[4-[2-[2-[2-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]sulfonylamino]-~{N}-(cyclohexylmethyl)-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, GLYCEROL, LYSINE, ...
著者Dawson, A, Wyllie, S.
登録日2022-04-25
公開日2022-09-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Acs Infect Dis., 8, 2022
6OD8
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BU of 6od8 by Molmil
Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Putative aspartyl-tRNA synthetase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-03-26
公開日2019-04-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
to be published
6C86
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BU of 6c86 by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
分子名称: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-01-24
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
to be published
6CHD
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BU of 6chd by Molmil
Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
分子名称: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, ...
著者Dranow, D.M, Abendroth, J, Lorimer, D.D.
登録日2018-02-22
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine
to be published
1N9W
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BU of 1n9w by Molmil
Crystal structure of the non-discriminating and archaeal-type aspartyl-tRNA synthetase from Thermus thermophilus
分子名称: aspartyl-tRNA synthetase 2
著者Charron, C, Roy, H, Blaise, M, Giege, R, Kern, D.
登録日2002-11-26
公開日2003-04-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain
EMBO J., 22, 2003
6PQH
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BU of 6pqh by Molmil
Crystal structure of Asparagine-tRNA ligase from Elizabethkingia sp. CCUG 26117
分子名称: 1,2-ETHANEDIOL, Asparagine--tRNA ligase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-07-09
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Asparagine-tRNA ligase from Elizabethkingia sp. CCUG 26117
TO BE PUBLISHED
6SJC
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BU of 6sjc by Molmil
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine
分子名称: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, Aspartate--tRNA(Asp) ligase
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2019-08-13
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
7AP4
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BU of 7ap4 by Molmil
Thermus thermophilus Aspartyl-tRNA Synthetase in Complex with Compound AspS7HMDDA
分子名称: (3~{S})-3-azanyl-4-[[(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxysulfonylamino]-4-oxidanylidene-butanoic acid, Aspartate--tRNA(Asp) ligase
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2020-10-15
公開日2020-12-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.
Molecules, 25, 2020
7EA9
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BU of 7ea9 by Molmil
Crystal Structure of human lysyl-tRNA synthetase Y145H mutant
分子名称: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, Lysine--tRNA ligase
著者Wu, S, Hei, Z, Zheng, L, Zhou, J, Liu, Z, Wang, J, Fang, P.
登録日2021-03-06
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment.
Biochem.Biophys.Res.Commun., 554, 2021
4H02
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BU of 4h02 by Molmil
Crystal structure of P. falciparum Lysyl-tRNA synthetase
分子名称: Lysyl-tRNA synthetase
著者Khan, S, Garg, A, Sharma, A.
登録日2012-09-07
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献Structural analysis of malaria-parasite lysyl-tRNA synthetase provides a platform for drug development.
Acta Crystallogr.,Sect.D, 69, 2013
7BT5
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BU of 7bt5 by Molmil
Crystal structure of plasmodium LysRS complexing with an antitumor compound
分子名称: LYSINE, Lysine--tRNA ligase, N4-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-N2-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
著者Zhou, J, Wang, J, Fang, P.
登録日2020-03-31
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Inhibition of Plasmodium falciparum Lysyl-tRNA synthetase via an anaplastic lymphoma kinase inhibitor.
Nucleic Acids Res., 48, 2020
7F6W
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BU of 7f6w by Molmil
Crystal structure of Saccharomyces cerevisiae lysyl-tRNA Synthetase
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine--tRNA ligase
著者Wu, S, Li, P, Hei, Z, Zheng, L, Wang, J, Fang, P.
登録日2021-06-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.607 Å)
主引用文献Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex.
Cell.Mol.Life Sci., 79, 2022

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