5MG5
 
 | | A multi-component acyltransferase PhlABC from Pseudomonas protegens soaked with the monoacetylphloroglucinol (MAPG) | | 分子名称: | 2,4-diacetylphloroglucinol biosynthesis protein, 2,4-diacetylphloroglucinol biosynthesis protein PhlC, Hydroxymethylglutaryl-CoA synthase, ... | | 著者 | Pavkov-Keller, T, Schmidt, N.G, Kroutil, W, Gruber, K. | | 登録日 | 2016-11-20 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | | 主引用文献 | Structure and Catalytic Mechanism of a Bacterial Friedel-Crafts Acylase.
Chembiochem, 20, 2019
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4YZO
 | | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Padmanabhan, B, Manjula, R, Yokoyama, S, Bessho, Y. | | 登録日 | 2015-03-25 | | 公開日 | 2016-03-30 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii
To Be Published
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8PF8
 | | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-72 | | 分子名称: | (2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... | | 著者 | Dalwani, S, Wierenga, R.K, Venkatesan, R. | | 登録日 | 2023-06-15 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
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3GOA
 | | Crystal structure of the Salmonella typhimurium FadA 3-ketoacyl-CoA thiolase | | 分子名称: | 3-ketoacyl-CoA thiolase, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Anderson, S.M, Skarina, T, Onopriyenko, O, Wawrzak, Z, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-03-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 |
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7FEA
 | | PY14 in complex with Col-D | | 分子名称: | (6~{R},7~{R},9~{E})-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase | | 著者 | Lin, C.C, Ko, T.P, Huang, K.F, Yang, Y.L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors.
Commun Biol, 5, 2022
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1AFW
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5ONC
 | | Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch | | 分子名称: | CHLORIDE ION, Steroid 3-ketoacyl-CoA thiolase | | 著者 | Schaefer, C, Kuper, J, Sampson, N.S, Kisker, C. | | 登録日 | 2017-08-03 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch.
ACS Infect Dis, 3, 2017
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2VTZ
 | | Biosynthetic thiolase from Z. ramigera. Complex of the C89A mutant with coenzyme A. | | 分子名称: | ACETYL-COA ACETYLTRANSFERASE, COENZYME A, SULFATE ION | | 著者 | Kursula, P, Merilainen, G, Wierenga, R.K. | | 登録日 | 2008-05-19 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme.
FEBS J., 275, 2008
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8ECM
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7PYT
 | | Benzoylsuccinyl-CoA thiolase with coenzyme A | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Benzoylsuccinyl-CoA thiolase subunit, ... | | 著者 | Ermler, U, Heider, J, Weidenweber, S, Demmer, U. | | 登録日 | 2021-10-11 | | 公開日 | 2022-04-06 | | 最終更新日 | 2022-09-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism.
Febs J., 289, 2022
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7PXP
 | | Benzoylsuccinyl-CoA thiolase | | 分子名称: | Benzoylsuccinyl-CoA thiolase subunit, ZINC ION | | 著者 | Ermler, U, Heider, H, Weidenweber, S, Demmer, U. | | 登録日 | 2021-10-08 | | 公開日 | 2022-04-06 | | 最終更新日 | 2022-09-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism.
Febs J., 289, 2022
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7CW4
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5F0V
 | | X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution | | 分子名称: | 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase | | 著者 | Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N. | | 登録日 | 2015-11-28 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.
Acta Crystallogr.,Sect.F, 72, 2016
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5F38
 | | X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution | | 分子名称: | 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase, COENZYME A, ... | | 著者 | Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N. | | 登録日 | 2015-12-02 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.
Acta Crystallogr.,Sect.F, 72, 2016
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7CW5
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8GQF
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5XYJ
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5XZ5
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1DLU
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1DM3
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1DLV
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1OU6
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8BNU
 | | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex | | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | | 登録日 | 2022-11-14 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
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8BRJ
 | | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex | | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | | 登録日 | 2022-11-23 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
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8BNR
 | | Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex | | 分子名称: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | | 著者 | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | | 登録日 | 2022-11-14 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (10.3 Å) | | 主引用文献 | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes.
Structure, 31, 2023
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