PDB: 120 件ウェブページステータス検索Chemie searchBIRD

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5HPG	STRUCTURE AND LIGAND DETERMINANTS OF THE RECOMBINANT KRINGLE 5 DOMAIN OF HUMAN PLASMINOGEN 分子名称: PLASMINOGEN 著者 Tulinsky, A, Mochalkin, I, Castellino, F.J. 登録日 1997-09-19 公開日 1998-03-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen. Biochemistry, 37, 1998
1B2I	KRINGLE 2 DOMAIN OF HUMAN PLASMINOGEN: NMR SOLUTION STRUCTURE OF TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID (AMCHA) COMPLEX 分子名称: PROTEIN (PLASMINOGEN), TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID 著者 Marti, D.N, Schaller, J, Llinas, M. 登録日 1999-09-24 公開日 1999-11-19 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of the plasminogen kringle 2-AMCHA complex: 3(1)-helix in homologous domains. Biochemistry, 38, 1999
7TNG	Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) 分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1 著者 Guarino, S.R, Di Bello, A, Palamini, M, Forneris, F. 登録日 2022-01-21 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1) Acta Crystallogr.,Sect.F, 78, 2022
1TPK	CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION 分子名称: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR 著者 De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A. 登録日 1991-09-24 公開日 1992-07-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution. Biochemistry, 31, 1992
6RX7	Structure of the KIV type 2 (KIV-2) domain of lipoprotein (a) 分子名称: Apolipoprotein(a), GLYCEROL, SULFATE ION 著者 Santonastaso, A, Maggi, M, Scotti, C. 登録日 2019-06-07 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 High resolution structure of human apolipoprotein (a) kringle IV type 2: beyond the lysine binding site. J.Lipid Res., 61, 2020
1URK	SOLUTION STRUCTURE OF THE AMINO TERMINAL FRAGMENT OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR 分子名称: PLASMINOGEN ACTIVATOR, alpha-L-fucopyranose 著者 Hansen, A.P, Petros, A.M, Meadows, R.P, Nettesheim, D.G, Mazar, A.P, Olejniczak, E.T, Xu, R.X, Pederson, T.M, Henkin, J, Fesik, S.W. 登録日 1994-01-10 公開日 1995-05-08 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator. Biochemistry, 33, 1994
4KIV	RECOMBINANT KRINGLE IV-10/W72R MUTANT OF HUMAN APOLIPOPROTEIN(A) 分子名称: APOLIPOPROTEIN 著者 Mochalkin, I, Tulinsky, A, Scanu, A. 登録日 1998-08-26 公開日 1999-05-18 最終更新日 2018-03-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry, 38, 1999
1CEA	THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH EACA (EPSILON-AMINOCAPROIC ACID) 分子名称: 6-AMINOHEXANOIC ACID, PLASMINOGEN 著者 Tulinsky, A, Mathews, I.I. 登録日 1995-12-03 公開日 1996-04-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid. Biochemistry, 35, 1996
1CEB	THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH AMCHA (TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID) 分子名称: PLASMINOGEN, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID 著者 Tulinsky, A, Mathews, I.I. 登録日 1995-12-03 公開日 1996-04-03 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid. Biochemistry, 35, 1996
3KIV	RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A) 分子名称: 6-AMINOHEXANOIC ACID, APOLIPOPROTEIN 著者 Mochalkin, I, Tulinsky, A, Scanu, A. 登録日 1998-09-08 公開日 1999-05-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry, 38, 1999
5Z55	NMR Solution Structure of the Kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1) 分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1 著者 Ma, X, Hu, K.F. 登録日 2018-01-17 公開日 2018-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1). Biomol NMR Assign, 12, 2018
6BA5	Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1 分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain Heavy chain, antibody R11, ... 著者 Park, H, Rader, C. 登録日 2017-10-12 公開日 2018-06-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BAN	Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1 分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain R11 Heavy chain, Variable domain of R11 Light Chain 著者 Park, H, Rader, C. 登録日 2017-10-14 公開日 2018-06-13 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2PK4	THE REFINED STRUCTURE OF THE EPSILON-AMINOCAPROIC ACID COMPLEX OF HUMAN PLASMINOGEN KRINGLE 分子名称: 6-AMINOHEXANOIC ACID, HUMAN PLASMINOGEN KRINGLE 4 著者 Tulinsky, A, Wu, T.-P. 登録日 1991-07-18 公開日 1993-10-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4. Biochemistry, 30, 1991
6OSV	Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 分子名称: Antibody heavy chain variable region, Antibody light chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 著者 Park, H, Rader, C. 登録日 2019-05-02 公開日 2020-04-01 最終更新日 2020-05-13 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
6OSH	Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 分子名称: Antibody Light chain variable region, Antibody heavy chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 著者 Park, H, Rader, C. 登録日 2019-05-01 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.117 Å) 主引用文献 Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
6OSN	Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 分子名称: ACETATE ION, Tyrosine-protein kinase transmembrane receptor ROR2 著者 Park, H, Rader, C. 登録日 2019-05-01 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.083 Å) 主引用文献 Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
2FEB	NMR Solution Structure, Dynamics and Binding Properties of the Kringle IV Type 8 module of apolipoprotein(a) 分子名称: Apolipoprotein(a) 著者 Chitayat, S, Kanelis, V, Koschinsky, M.L, Smith, S.P. 登録日 2005-12-15 公開日 2006-12-26 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a). Biochemistry, 46, 2007
7OCM	K1K1H6, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hepatocyte growth factor alpha chain,Hepatocyte growth factor alpha chain 著者 de Jonge, H, de Nola, G, Gherardi, E. 登録日 2021-04-27 公開日 2021-07-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist. Life Sci Alliance, 5, 2022
7OCL	K1K1, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic 分子名称: Hepatocyte growth factor alpha chain,Hepatocyte growth factor alpha chain 著者 de Jonge, H, de Nola, G, Gherardi, E. 登録日 2021-04-27 公開日 2021-07-21 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist. Life Sci Alliance, 5, 2022
1PK4	CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN PLASMINOGEN KRINGLE 4 REFINED AT 1.9-ANGSTROMS RESOLUTION 分子名称: PLASMINOGEN KRINGLE 4, SULFATE ION 著者 Tulinsky, A, Mulichak, A.M. 登録日 1991-07-18 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution. Biochemistry, 30, 1991
1PKR	THE STRUCTURE OF RECOMBINANT PLASMINOGEN KRINGLE 1 AND THE FIBRIN BINDING SITE 分子名称: CHLORIDE ION, PLASMINOGEN 著者 Wu, T.-P, Tulinsky, A. 登録日 1993-08-03 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 The structure of recombinant plasminogen kringle 1 and the fibrin binding site. Blood Coagulation Fibrinolysis, 5, 1994
1PML	KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES 分子名称: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR KRINGLE 2 著者 Padmanabhan, K, Tulinsky, A. 登録日 1994-04-25 公開日 1994-06-22 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Kringle-kringle interactions in multimer kringle structures. Protein Sci., 3, 1994
2I9A	Crystal structure of the free aminoterminal fragment of urokinase type plasminogen activator (ATF) 分子名称: PHOSPHATE ION, Urokinase-type plasminogen activator 著者 Lubkowski, J, Barinka, C. 登録日 2006-09-05 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis of interaction between urokinase-type plasminogen activator and its receptor. J.Mol.Biol., 363, 2006
1PMK	KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES 分子名称: PLASMINOGEN KRINGLE 4 著者 Padmanabhan, K, Tulinsky, A. 登録日 1994-04-25 公開日 1994-06-22 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Kringle-kringle interactions in multimer kringle structures. Protein Sci., 3, 1994

 

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