PDB: 433 件ウェブページステータス検索Chemie searchBIRD

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4XC4	Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide 分子名称: CHLORIDE ION, Insulin, SODIUM ION, ... 著者 Bracey, A.W, Magis, A.T, Buschard, K, Osterbye, T, Bailey, K.M, Ostrov, D.A. 登録日 2014-12-17 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide To Be Published
1BQT	THREE-DIMENSIONAL STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR-I (IGF-I) DETERMINED BY 1H-NMR AND DISTANCE GEOMETRY, 6 STRUCTURES 分子名称: INSULIN-LIKE GROWTH FACTOR-I 著者 Sato, A, Nishimura, S, Ohkubo, T, Kyogoku, Y, Koyama, S, Kobayashi, M, Yasuda, T, Kobayashi, Y. 登録日 1998-08-18 公開日 1999-05-18 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry. Int.J.Pept.Protein Res., 41, 1993
1CPH	CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 分子名称: 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION 著者 Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. 登録日 1992-10-30 公開日 1993-01-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
7INS	STRUCTURE OF PORCINE INSULIN COCRYSTALLIZED WITH CLUPEINE Z 分子名称: GENERAL PROTAMINE CHAIN, INSULIN (CHAIN A), INSULIN (CHAIN B), ... 著者 Balschmidt, P, Hansen, F.B, Dodson, E, Dodson, G, Korber, F. 登録日 1991-09-03 公開日 1994-01-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of porcine insulin cocrystallized with clupeine Z. Acta Crystallogr.,Sect.B, 47, 1991
7JP3	Des-B29,B30-insulin 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, PHENOL, ... 著者 Yoder, J, Weiss, M.A, DiMarchi, R, Zaykov, A. 登録日 2020-08-07 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Des-B29,B30-insulin To Be Published
7NHU	Crystal structure of desB30 insulin produced by cell free protein synthesis 分子名称: Insulin 著者 Johansson, E. 登録日 2021-02-11 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein. Protein Expr.Purif., 186, 2021
4RXW	Crystal Structure of the cobalt human insulin derivative 分子名称: COBALT (II) ION, Insulin A chain, Insulin B chain 著者 Prugovecki, B, Ivetic, N, Matkovic-Calogovic, D. 登録日 2014-12-12 公開日 2015-01-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of the cobalt human insulin derivative TO BE PUBLISHED
4UNH	Human insulin B26Gly mutant crystal structure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION 著者 Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. 登録日 2014-05-28 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
4UNE	Human insulin B26Phe mutant crystal structure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION 著者 Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. 登録日 2014-05-28 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
4UNG	Human insulin B26Asn mutant crystal structure 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION 著者 Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. 登録日 2014-05-28 公開日 2014-10-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
7ELJ	Prion Derived Tetrapeptide Stabilizes Thermolabile Insulin via Conformational Trapping 分子名称: IS1, Insulin A Chain, Insulin B chain 著者 Banerjee, N. 登録日 2021-04-11 公開日 2021-04-28 最終更新日 2021-07-07 実験手法 SOLUTION NMR 主引用文献 Prion-derived tetrapeptide stabilizes thermolabile insulin via conformational trapping. Iscience, 24, 2021
7Z5Q	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP) 分子名称: Insulin, Insulin A chain, SULFATE ION 著者 van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
7Z5L	Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO) 分子名称: GLYCEROL, Insulin A chain, Insulin B chain, ... 著者 van den Elsen, J.M.H, Wahid, A.A, Crennell, C. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling To Be Published
5HPU	Insulin with proline analog HyP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin, chain A, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
5HRQ	Insulin with proline analog HzP at position B28 in the R6 state 分子名称: CHLORIDE ION, Insulin A-Chain, Insulin B-Chain, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-24 公開日 2017-01-25 最終更新日 2020-01-15 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
5HPR	Insulin with proline analog HyP at position B28 in the T2 state 分子名称: GLYCEROL, Insulin A-Chain, Insulin B-Chain, ... 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
5HQI	Insulin with proline analog HzP at position B28 in the T2 state 分子名称: Insulin A-Chain, Insulin B-Chain 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
6U46	Solution Structure of a Heat-Resistant Long-Acting Insulin Analog 分子名称: Insulin 著者 Yang, Y, Weiss, M.A. 登録日 2019-08-23 公開日 2020-08-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution Structure of a Heat-Resistant Long-Acting Insulin Analog To Be Published
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
5D53	In meso in situ serial X-ray crystallography structure of insulin at 100 K 分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Insulin A chain, Insulin B chain, ... 著者 Huang, C.-Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M. 登録日 2015-08-10 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures. Acta Crystallogr D Struct Biol, 72, 2016
5E7W	X-ray Structure of Human Recombinant 2Zn insulin at 0.92 Angstrom 分子名称: ACETATE ION, Insulin, N-PROPANOL, ... 著者 Lisgarten, D.R, Naylor, C.E, Palmer, R.A, Lobley, C.M.C. 登録日 2015-10-13 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.9519 Å) 主引用文献 Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K. Chem Cent J, 11, 2017
5ENA	Xray crystal structure of isotope-labeled human insulin 分子名称: Insulin chain A, Insulin chain B 著者 Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. 登録日 2015-11-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
6Z7Y	Human insulin in complex with the analytical antibody OXI-005 Fab 分子名称: Insulin, OXI-005 Fab Heavy chain, OXI-005 Fab Light chain 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
5EMS	Crystal Structure of an iodinated insulin analog 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Lawrence, M.C, Pandyarajan, V, Wan, Z, Weiss, M.A. 登録日 2015-11-06 公開日 2016-11-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY. J. Biol. Chem., 291, 2016
5EN9	High resolution x-ray crystal structure of isotope-labeled ester-insulin 分子名称: Insulin chain A, Insulin chain B 著者 Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. 登録日 2015-11-09 公開日 2016-01-13 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016

 

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