8D9Y
 
 | | Crystal structure of Taipan alpha-neurotoxin in complex with Centi-3FTX-D09 antibody | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Centi-3FTX-D09 Fab heavy chain, ... | | 著者 | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | | 登録日 | 2022-06-12 | | 公開日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
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6AEX
 | | Crystal structure of unoccupied murine uPAR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | | 著者 | Min, L, Huang, M. | | 登録日 | 2018-08-06 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | | 主引用文献 | Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit.
Febs Lett., 593, 2019
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1KXI
 | | STRUCTURE OF CYTOTOXIN HOMOLOG PRECURSOR | | 分子名称: | CARDIOTOXIN V | | 著者 | Sun, Y.-J, Wu, W.-G, Chiang, C.-M, Hsin, A.-Y, Hsiao, C.-D. | | 登録日 | 1996-08-29 | | 公開日 | 1997-04-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal structure of cardiotoxin V from Taiwan cobra venom: pH-dependent conformational change and a novel membrane-binding motif identified in the three-finger loops of P-type cardiotoxin.
Biochemistry, 36, 1997
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1CDR
 | | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 | | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | | 登録日 | 1994-06-01 | | 公開日 | 1994-09-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
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3PLC
 | | Crystal structure of Beta-Cardiotoxin, a novel three-finger cardiotoxin from the venom of Ophiophagus hannah | | 分子名称: | Beta-cardiotoxin OH-27 | | 著者 | Roy, A, Qingxiang, S, Kini, R.M, Sivaraman, J. | | 登録日 | 2010-11-15 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Identification of a alpha-helical molten globule intermediate and structural characterization of beta-cardiotoxin, an all beta-sheet protein isolated from the venom of Ophiophagus hannah (king cobra).
Protein Sci., 28, 2019
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7V63
 | | Structure of dimeric uPAR at low pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | | 著者 | Yuan, C, Huang, M. | | 登録日 | 2021-08-19 | | 公開日 | 2021-12-22 | | 最終更新日 | 2022-04-06 | | 実験手法 | X-RAY DIFFRACTION (2.906 Å) | | 主引用文献 | Crystal structure and cellular functions of uPAR dimer
Nat Commun, 13, 2022
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1YWH
 | | crystal structure of urokinase plasminogen activator receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Llinas, P, Le Du, M.H, Gardsvoll, H, Dano, K, Ploug, M, Gilquin, B, Stura, E.A, Menez, A. | | 登録日 | 2005-02-18 | | 公開日 | 2005-05-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
EMBO J., 24, 2005
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4QTI
 | | Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 | | 分子名称: | Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... | | 著者 | Zhao, B, Yuan, C, Luo, Z, Huang, M. | | 登録日 | 2014-07-08 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation.
J.Mol.Biol., 427, 2015
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1ERH
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS | | 分子名称: | CD59 | | 著者 | Kieffer, B, Driscoll, P.C, Campbell, I.D, Willis, A.C, Van Der Merwe, P.A, Davis, S.J. | | 登録日 | 1993-12-13 | | 公開日 | 1994-04-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.
Biochemistry, 33, 1994
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3U74
 | | Crystal structure of stabilized human uPAR mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | | 著者 | Huang, M.D, Xu, X, Yuan, C. | | 登録日 | 2011-10-13 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Crystal structure of the urokinase receptor in a ligand-free form.
J.Mol.Biol., 416, 2012
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6ION
 | | The complex of C4.4A with its antibody 11H10 Fab fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ly6/PLAUR domain-containing protein 3, ... | | 著者 | Huang, M.D, Jiang, Y.B, Yuan, C, Lin, L. | | 登録日 | 2018-10-30 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/alpha-neurotoxin Domain
Int J Biol Sci, 16, 2020
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6IOM
 | | Crystal structure of human C4.4A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ly6/PLAUR domain-containing protein 3 | | 著者 | Huang, M.D, Jiang, Y.B, Yuan, C, Lin, L. | | 登録日 | 2018-10-30 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | | 主引用文献 | Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/alpha-neurotoxin Domain
Int J Biol Sci, 16, 2020
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1ERG
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS | | 分子名称: | CD59 | | 著者 | Kieffer, B, Driscoll, P.C, Campbell, I.D, Willis, A.C, Van Der Merwe, P.A, Davis, S.J. | | 登録日 | 1993-12-13 | | 公開日 | 1994-04-30 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.
Biochemistry, 33, 1994
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7QFC
 | | Crystal structure of cytotoxin 13 from Naja naja, orthorhombic form | | 分子名称: | Cytotoxin 13 | | 著者 | Samygina, V.R, Dubova, K.M, Bourenkov, G, Utkin, Y.N, Dubovskii, P.V. | | 登録日 | 2021-12-05 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Variability in the Spatial Structure of the Central Loop in Cobra Cytotoxins Revealed by X-ray Analysis and Molecular Modeling.
Toxins, 14, 2022
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7QHI
 | | Crystal structure of cytotoxin 13 from Naja naja, hexagonal form | | 分子名称: | Cytotoxin 13 | | 著者 | Samygina, V.R, Dubova, K.M, Bourenkov, G, Utkin, Y.N, Dubovskii, P.V. | | 登録日 | 2021-12-12 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Variability in the Spatial Structure of the Central Loop in Cobra Cytotoxins Revealed by X-ray Analysis and Molecular Modeling.
Toxins, 14, 2022
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2J8B
 | | High resolution structure of human CD59 | | 分子名称: | CD59 GLYCOPROTEIN | | 著者 | Leath, K.J, Johnson, S, Roversi, P, Morgan, B.P, Smith, R.A.G, Lea, S.M. | | 登録日 | 2006-10-24 | | 公開日 | 2007-08-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | High-Resolution Structures of Bacterially Expressed Soluble Human Cd59.
Acta Crystallogr.,Sect.F, 63, 2007
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1CDS
 | | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 | | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | | 登録日 | 1994-06-01 | | 公開日 | 1994-09-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
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1CDQ
 | | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | | 分子名称: | CD59 | | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | | 登録日 | 1994-06-01 | | 公開日 | 1994-09-30 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59.
Structure, 2, 1994
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1CVO
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7BPR
 | | Crystal structure of human TEX101 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PLATINUM (II) ION, Testis-expressed protein 101 | | 著者 | Masutani, M, Sakurai, S, Shimizu, T, Ohto, U. | | 登録日 | 2020-03-23 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-12-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains.
Febs Lett., 594, 2020
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7BPS
 | | Crystal structure of mouse TEX101 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Testis-expressed protein 101, ... | | 著者 | Masutani, M, Sakurai, S, Shimizu, T, Ohto, U. | | 登録日 | 2020-03-23 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains.
Febs Lett., 594, 2020
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6ZZE
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6ZZF
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7E17
 | | Structure of dimeric uPAR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | | 著者 | Cai, Y, Huang, M. | | 登録日 | 2021-02-01 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Crystal structure and cellular functions of uPAR dimer
Nat Commun, 13, 2022
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2N99
 | | Solution structure of the SLURP-2, a secreted isoform of Lynx1 | | 分子名称: | Ly-6/neurotoxin-like protein 1 | | 著者 | Paramonov, A.S, Shenkarev, Z.O, Lyukmanova, E.N, Arseniev, A.S. | | 登録日 | 2015-11-11 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors.
Sci Rep, 6, 2016
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