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8KDX
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BU of 8kdx by Molmil
Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current
分子名称: Microtubule-associated protein tau, Tyrosine-protein kinase Fyn
著者Padavattan, S, Jos, S.
登録日2023-08-10
公開日2024-02-28
実験手法X-RAY DIFFRACTION (1.01 Å)
主引用文献Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current.
J.Mol.Biol., 436, 2024
7JT9
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BU of 7jt9 by Molmil
Fgr SH3 domain crystal structure
分子名称: Tyrosine-protein kinase Fgr
著者Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M.
登録日2020-08-17
公開日2022-01-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr.
J.Mol.Biol., 434, 2022
6NMW
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BU of 6nmw by Molmil
Crystal structure of the human Lyn SH3 domain
分子名称: Tyrosine-protein kinase Lyn
著者Berndt, S, Gurevich, V.V, Iverson, T.M.
登録日2019-01-12
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
PLoS ONE, 14, 2019
6IPY
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BU of 6ipy by Molmil
His-tagged Fyn SH3 domain R96I mutant
分子名称: Tyrosine-protein kinase Fyn
著者Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
登録日2018-11-05
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.343 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
6IPZ
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BU of 6ipz by Molmil
Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn
著者Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
登録日2018-11-05
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.576 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
5UL6
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BU of 5ul6 by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
分子名称: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus
著者Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
登録日2017-01-24
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
5VEI
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BU of 5vei by Molmil
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
分子名称: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-04-04
公開日2017-08-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
4Y92
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Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
分子名称: GLYCEROL, Protein-tyrosine kinase, SULFATE ION, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2015-02-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
to be published
6RO9
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Human spectrin SH3 domain D48G, E7V, K60V
分子名称: Spectrin alpha, non-erythrocytic 1
著者Reverter, D, Navarro, S, Ventura, S.
登録日2019-05-10
公開日2020-06-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.814 Å)
主引用文献Human spectrin SH3 domain D48G, E7V, K60V
To Be Published
6EDF
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BU of 6edf by Molmil
Fragment of a tyrosine-protein kinase
分子名称: FYN, GLYCEROL, UNKNOWN ATOM OR ION
著者Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC)
登録日2018-08-09
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Fragment of a tyrosine-protein kinase
To be Published
6SCW
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BU of 6scw by Molmil
SH3-subunit of chicken alpha spectrin solved by NMR
分子名称: Spectrin alpha chain, non-erythrocytic 1 isoform X11
著者Grohe, K, Hebrank, C, Linser, R.
登録日2019-07-25
公開日2020-08-12
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献Protein Motional Details Revealed by Complementary Structural Biology Techniques.
Structure, 28, 2020
6SDF
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BU of 6sdf by Molmil
N-terminal SH3 domain of Grb2 protein
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2
著者Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B.
登録日2019-07-26
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
4ZNX
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BU of 4znx by Molmil
Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12
分子名称: APP12, Tyrosine-protein kinase Fyn
著者Camara-Artigas, A.
登録日2015-05-05
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Acta Crystallogr.,Sect.F, 72, 2016
8WFF
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BU of 8wff by Molmil
The Crystal Structure of LYN from Biortus.
分子名称: CHLORIDE ION, CITRATE ANION, Tyrosine-protein kinase Lyn
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y.
登録日2023-09-19
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The Crystal Structure of LYN from Biortus.
To Be Published
5L23
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BU of 5l23 by Molmil
Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand
分子名称: Adapter molecule crk, C3G derived peptide, DI(HYDROXYETHYL)ETHER
著者Bhatt, V.S, Krieger, I, Sacchettini, J, Cho, J.-H.
登録日2016-07-30
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of the complex between the N-terminal SH3 domain of CrkII and a proline-rich ligand
To Be Published
7NES
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BU of 7nes by Molmil
Crystal structure of the v-Src SH3 domain N117D-V124L mutant
分子名称: GLYCINE, v-Src SH3 domain
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2021-06-16
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7NER
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BU of 7ner by Molmil
Crystal structure of the v-Src SH3 domain Q128R mutant
分子名称: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7NET
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Crystal structure of the v-Src SH3 domain W95R-I96T mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7NZC
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BU of 7nzc by Molmil
First SH3 domain of POSH (Plenty of SH3 Domains protein)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase SH3RF1
著者Palencia, A, Bessa, L.M, Jensen, M.R.
登録日2021-03-23
公開日2021-12-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.111 Å)
主引用文献Visualizing protein breathing motions associated with aromatic ring flipping.
Nature, 602, 2022
7Y4N
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BU of 7y4n by Molmil
Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos
分子名称: Growth factor receptor-bound protein 2
著者Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y.
登録日2022-06-15
公開日2022-08-31
実験手法SOLUTION NMR
主引用文献Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
Biochem.Biophys.Res.Commun., 625, 2022
7YXW
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BU of 7yxw by Molmil
Structure of the p22phox A200G mutant in complex with p47phox peptide
分子名称: Cytochrome b-245 light chain, Neutrophil cytosol factor 1
著者Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z.
登録日2022-02-16
公開日2022-03-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Acs Med.Chem.Lett., 13, 2022
5NP3
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BU of 5np3 by Molmil
Abl2 SH3
分子名称: Abelson tyrosine-protein kinase 2
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP5
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BU of 5np5 by Molmil
Abl2 SH3 pTyr116/161
分子名称: Abelson tyrosine-protein kinase 2, SULFATE ION
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
6XVM
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BU of 6xvm by Molmil
Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2
分子名称: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
4EIK
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Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12
分子名称: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide
著者Camara-Artigas, A.
登録日2012-04-05
公開日2013-04-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016

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件を2024-04-24に公開中

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