8RGR
| Closed Complex I from murine liver | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Vercellino, I, Sazanov, L.A. | 登録日 | 2023-12-14 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
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8RGT
| Open Complex I from murine brain | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Vercellino, I, Sazanov, L.A. | 登録日 | 2023-12-14 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
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8RIL
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8RJ3
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8RJW
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8RK2
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8RKS
| Structure of VPS29-VPS35 bound to the LFa motif R21 of Fam21. | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, WASH complex subunit 2A | 著者 | Romano-Moreno, M, Astorga-Simon, E.N, Rojas, A.L, Hierro, A. | 登録日 | 2023-12-30 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21. Protein Sci., 33, 2024
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8RM6
| Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: C3(1)ARE | 分子名称: | C3(1)ARE_Chain C, C3(1)ARE_Chain D, Isoform 2 of Androgen receptor, ... | 著者 | Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F. | 登録日 | 2024-01-05 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241, 2024
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8RM7
| Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: MMTV-177 GRE/ARE | 分子名称: | Isoform 2 of Androgen receptor, MMTV-177 GRE/ARE Chain C, MMTV-177 GRE/ARE, ... | 著者 | Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F. | 登録日 | 2024-01-05 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241, 2024
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8RRQ
| Crystal structure of human SYK in complex with compound 24 | 分子名称: | GLYCEROL, N-[(1S,2R)-2-azanylcyclohexyl]-5-[2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl]-2-methyl-pyrazole-3-carboxamide, Tyrosine-protein kinase SYK | 著者 | Canevari, G. | 登録日 | 2024-01-23 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors. Eur.J.Med.Chem., 270, 2024
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8RRZ
| Crystal structure of SYK kinase in complex with compound 1 | 分子名称: | GLYCEROL, N-[(2S)-1-(azetidin-1-yl)propan-2-yl]-3-{2-[(3,5-dimethoxyphenyl)amino]pyrimidin-4-yl}-1-methyl-1H-pyrazole-5-carboxamide, Tyrosine-protein kinase SYK | 著者 | Canevari, G. | 登録日 | 2024-01-24 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors. Eur.J.Med.Chem., 270, 2024
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8RUU
| Fabs derived from bimekizumab in complex with IL-17F | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoblobulin heavy chain, Immunoblobulin light chain, ... | 著者 | Adams, R, Lawson, A.D.G. | 登録日 | 2024-01-31 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition J Invest Dermatol., 2024
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8S7C
| Ternary Complex of Cachd1, FZD5 and LRP6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-5, ... | 著者 | Zhao, Y, Ren, J, Jones, E.Y. | 登録日 | 2024-02-29 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (4.7 Å) | 主引用文献 | Cachd1 is a Frizzled- and LRP6-interacting protein required for neurons to acquire left-right asymmetric character Science, 2024
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8S9T
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8S9U
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8S9V
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8S9X
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8SDE
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8SDI
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8SDJ
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8SGB
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8SGI
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8SGM
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8SHB
| Crystal Structure of PRMT3 with Compound YD1-208 | 分子名称: | 5'-S-[3-(N'-phenylcarbamimidamido)propyl]-5'-thioadenosine, Protein arginine N-methyltransferase 3 | 著者 | Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2023-04-13 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal Structure of PRMT3 with Compound YD1-208 To be published
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8SHK
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