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6X7H	Cyanovirin-N Mutation I34Y with Dimannose bound Descriptor: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose Authors: Fromme, R, Sharma, P, Ghirlanda, G. Deposit date: 2020-05-30 Release date: 2021-06-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations. Elife, 11, 2022
3LHC	Crystal structure of cyanovirin-n swapping domain b mutant Descriptor: Cyanovirin-N, PHOSPHATE ION, SODIUM ION Authors: Matei, E, Zheng, A, Furey, W, Rose, J, Aiken, C, Gronenborn, A.M. Deposit date: 2010-01-21 Release date: 2010-02-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization. J.Biol.Chem., 285, 2010
5K79	Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog Descriptor: 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER Authors: Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M. Deposit date: 2016-05-25 Release date: 2016-07-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure and Glycan Binding of a New Cyanovirin-N Homolog. J.Biol.Chem., 291, 2016
1LOM	CYANOVIRIN-N DOUBLE MUTANT P51S S52P Descriptor: CALCIUM ION, Cyanovirin-N, SULFATE ION Authors: Botos, I, Mori, T, Cartner, L.K, Boyd, M.R, Wlodawer, A. Deposit date: 2002-05-06 Release date: 2002-06-26 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Domain-swapped structure of a mutant of cyanovirin-N. Biochem.Biophys.Res.Commun., 294, 2002
2Z21	Crystal Structure of a five site mutated Cyanovirin-N Descriptor: Cyanovirin-N Authors: Fromme, R, Katilene, Z, Fromme, P, Ghirlanda, G. Deposit date: 2007-05-17 Release date: 2007-07-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity. Biochemistry, 46, 2007
1N02	Solution Structure of a Circular-Permuted Variant of the Potent HIV-inactivating Protein Cyanovirin-N Descriptor: Cyanovirin-N Authors: Barrientos, L.G, Gronenborn, A.M. Deposit date: 2002-10-10 Release date: 2002-12-18 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Solution Structure of a Circular-Permuted Variant of the Potent HIV-inactivating Protein Cyanovirin-N: Structural Basis for Protein Stability and Oligosaccharide Interaction J.Mol.Biol., 325, 2003
3S3Z	Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L10 Descriptor: SODIUM ION, Tandem Cyanovirin-N Dimer CVN2L10 Authors: Keeffe, J.R, Bjorkman, P.J, Mayo, S.L. Deposit date: 2011-05-18 Release date: 2011-08-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Designed oligomers of cyanovirin-N show enhanced HIV neutralization. Proc.Natl.Acad.Sci.USA, 108, 2011
3S3Y	Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L0 Descriptor: SODIUM ION, TANDEM CYANOVIRIN-N DIMER CVN2L0 Authors: Keeffe, J.R, Bjorkman, P.J, Mayo, S.L. Deposit date: 2011-05-18 Release date: 2011-08-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Designed oligomers of cyanovirin-N show enhanced HIV neutralization. Proc.Natl.Acad.Sci.USA, 108, 2011
3CZZ	Crystal structure of Cyanovirin-N domain B mutant Descriptor: Cyanovirin-N Authors: Matei, E, Furey, W, Gronenborn, A.M. Deposit date: 2008-04-30 Release date: 2008-08-19 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping. Structure, 16, 2008
2KJL	NMR structures of a designed Cyanovirin-N homolog lectin; LKAMG Descriptor: Cyanovirin-N homolog Authors: Koharudin, L.M.I, Gronenborn, A.M. Deposit date: 2009-05-31 Release date: 2009-06-23 Last modified: 2020-02-26 Method: SOLUTION NMR Cite: The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity. Structure, 16, 2008
2RDK	Five site mutated Cyanovirin-N with Mannose dimer bound Descriptor: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose Authors: Fromme, R, Katiliene, Z, Fromme, P, Ghirlanda, G. Deposit date: 2007-09-24 Release date: 2008-05-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution. Protein Sci., 17, 2008
2RP3	Solution Structure of Cyanovirin-N Domain B Mutant Descriptor: Cyanovirin-N Authors: Matei, E, Furey, W, Gronenborn, A.M. Deposit date: 2008-04-30 Release date: 2008-08-19 Last modified: 2021-11-10 Method: SOLUTION NMR Cite: Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping Structure, 16, 2008
2L2F	NMR Structure of GzCVNH (Gibberella zeae CVNH) Descriptor: Cyanovirin-N HOMOLOG Authors: Matei, E, Louis, J.M, Jee, J.G, Gronenborn, A.M. Deposit date: 2010-08-17 Release date: 2011-03-23 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: NMR solution structure of a cyanovirin homolog from wheat head blight fungus. Proteins, 79, 2011
1IIY	Solution NMR Structure of Complex of 1:2 Cyanovirin-N:Man-Alpha1,2-Man-Alpha Restrained Regularized Mean Coordinates Descriptor: CYANOVIRIN-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose Authors: Bewley, C.A. Deposit date: 2001-04-24 Release date: 2001-10-24 Last modified: 2020-07-29 Method: SOLUTION NMR Cite: Solution Structure of a Cyanovirin-N:Man alpha 1-2Man alpha Complex. Structural Basis for High Affinity Carbohydrate-Mediated Binding to gp120 Structure, 9, 2001
1J4V	CYANOVIRIN-N Descriptor: CYANOVIRIN-N Authors: Clore, G.M, Bewley, C.A. Deposit date: 2001-11-21 Release date: 2002-03-06 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings. J.Magn.Reson., 154, 2002
2Y1S	Microvirin lectin Descriptor: Mannan-binding lectin Authors: Bewley, C.A, Hussan, S. Deposit date: 2010-12-10 Release date: 2011-04-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity. J. Biol. Chem., 286, 2011
2YHH	Microvirin:mannobiose complex Descriptor: MANNAN-BINDING LECTIN, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose Authors: Hussan, S, Bewley, C.A, Clore, G.M, Gustchina, E, Ghirlando, R. Deposit date: 2011-05-02 Release date: 2011-06-15 Last modified: 2020-07-29 Method: SOLUTION NMR Cite: Solution Structure of the Monovalent Lectin Microvirin in Complex with Man(Alpha)(1-2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity. J.Biol.Chem., 286, 2011
1L5B	DOMAIN-SWAPPED CYANOVIRIN-N DIMER Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, cyanovirin-N Authors: Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. Deposit date: 2002-03-06 Release date: 2002-05-22 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
1L5E	The domain-swapped dimer of CV-N in solution Descriptor: Cyanovirin-N Authors: Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. Deposit date: 2002-03-06 Release date: 2002-06-05 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
2PYS	Crystal Structure of a Five Site Mutated Cyanovirin-N with a Mannose Dimer Bound at 1.8 A Resolution Descriptor: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose Authors: Fromme, R, Katilene, Z, Fromme, P, Ghirlanda, G. Deposit date: 2007-05-16 Release date: 2007-07-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity. Biochemistry, 46, 2007
2EZN	SOLUTION NMR STRUCTURE OF CYANOVIRIN-N ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES Descriptor: CYANOVIRIN-N Authors: Bewley, C.A, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-06 Release date: 1999-05-11 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of cyanovirin-N, a potent HIV-inactivating protein. Nat.Struct.Biol., 5, 1998
2EZM	SOLUTION NMR STRUCTURE OF CYANOVIRIN-N, RESTRAINED REGULARIZED MEAN COORDINATES Descriptor: CYANOVIRIN-N Authors: Bewley, C.A, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-06 Release date: 1999-05-11 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of cyanovirin-N, a potent HIV-inactivating protein. Nat.Struct.Biol., 5, 1998
4J4E	Structure of P51G Cyanovirin-N swapped trimer in the P212121 space group Descriptor: Cyanovirin-N Authors: Koharudin, L.M.I, Liu, L, Gronenborn, A.M. Deposit date: 2013-02-06 Release date: 2013-04-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates. Proc.Natl.Acad.Sci.USA, 110, 2013
4J4G	Structure of P51G Cyanovirin-N swapped tetramer in the C2 space group Descriptor: Cyanovirin-N Authors: Koharudin, L.M.I, Liu, L, Gronenborn, A.M. Deposit date: 2013-02-06 Release date: 2013-04-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates. Proc.Natl.Acad.Sci.USA, 110, 2013
4J4F	Structure of P51G Cyanovirin-N swapped tetramer in the P212121 space group Descriptor: Cyanovirin-N Authors: Koharudin, L.M.I, Liu, L, Gronenborn, A.M. Deposit date: 2013-02-06 Release date: 2013-04-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates. Proc.Natl.Acad.Sci.USA, 110, 2013

 

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