PDB: 93 resultsInfo pagesStatus searchChemie searchBIRD

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8B9N	Crystal structure of NEI domain of mouse NEIL3 trapped in covalent complex with ssDNA with abasic site Descriptor: Endonuclease 8-like 3, ZINC ION, ssDNA with abasic site Authors: Klima, M, Boura, E, Silhan, J. Deposit date: 2022-10-06 Release date: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of NEI domain of mouse NEIL3 trapped in covalent complex with ssDNA with abasic site To Be Published
8TH9	Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA Descriptor: DIMETHYL SULFOXIDE, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), ... Authors: Eckenroth, B.E, Doublie, S. Deposit date: 2023-07-14 Release date: 2023-11-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Structural and biochemical insights into NEIL2's preference for abasic sites. Nucleic Acids Res., 51, 2023
6VJI	Structure of mammalian NEIL2 from Monodelphis domestica Descriptor: Nei like DNA glycosylase 2, ZINC ION Authors: Eckenroth, B.E, Doublie, S. Deposit date: 2020-01-16 Release date: 2020-08-12 Last modified: 2021-01-20 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments. Structure, 29, 2021
7Z5A	Crystal structure of the trapped complex of mouse Endonuclease VIII-LIKE 3 (mNEIL3) and hairpin DNA with 5'overhang Descriptor: DNA (5'-D(P*TP*TP*TP*(PED)P*AP*CP*GP*CP*GP*AP*AP*GP*CP*GP*TP*G)-3'), Endonuclease 8-like 3, ZINC ION Authors: Silhan, J, Huskova, A. Deposit date: 2022-03-08 Release date: 2022-10-19 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model. Nucleic Acids Res., 50, 2022
4MB7	Crystal Structure of a viral DNA glycosylase Descriptor: Endonuclease 8-like L720, SULFATE ION, ZINC ION Authors: Prakash, A, Eckenroth, B.E, Doublie, S. Deposit date: 2013-08-19 Release date: 2013-10-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases. Dna Repair, 12, 2013
3W0F	Crystal structure of mouse Endonuclease VIII-LIKE 3 (mNEIL3) Descriptor: Endonuclease 8-like 3, IODIDE ION, ZINC ION Authors: Liu, M, Imamura, K, Averill, A.M, Wallace, S.S, Doublie, S. Deposit date: 2012-10-30 Release date: 2013-01-16 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA Structure, 21, 2013
3C58	Crystal structure of a complex between the wild-type lactococcus lactis Fpg (MutM) and a N7-Benzyl-Fapy-dG containing DNA Descriptor: DNA (5'-D(*DCP*DTP*DCP*DTP*DTP*DTP*(SOS)P*DTP*DTP*DTP*DCP*DTP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DAP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DGP*DA)-3'), DNA glycosylase, ... Authors: Coste, F, Castaing, B, Carell, T. Deposit date: 2008-01-31 Release date: 2008-12-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode Chem.Biol., 15, 2008
1EE8	CRYSTAL STRUCTURE OF MUTM (FPG) PROTEIN FROM THERMUS THERMOPHILUS HB8 Descriptor: MUTM (FPG) PROTEIN, ZINC ION Authors: Sugahara, M, Mikawa, T, Kumasaka, T, Yamamoto, M, Kato, R, Fukuyama, K, Inoue, Y, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2000-01-31 Release date: 2001-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8. EMBO J., 19, 2000
4CIS	Structure of MutM in complex with carbocyclic 8-oxo-G containing DNA Descriptor: (R,R)-2,3-BUTANEDIOL, DNA, FORMAMIDOPYRIMIDIN DNA GLYCOSYLASE, ... Authors: Schneider, S, Sadeghian, K, Flaig, D, Blank, I.D, Strasser, R, Stathis, D, Winnacker, M, Carell, T, Ochsenfeld, C. Deposit date: 2013-12-15 Release date: 2014-06-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Ribose-protonated DNA base excision repair: a combined theoretical and experimental study. Angew. Chem. Int. Ed. Engl., 53, 2014
2EA0	Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli in complex with AP-site containing DNA substrate Descriptor: 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', Endonuclease VIII, ... Authors: Golan, G, Zharov, D.O, Grollman, A.P, Shoham, G. Deposit date: 2007-01-29 Release date: 2008-02-26 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrate and mutations of critical residues To be Published
1TDZ	Crystal Structure Complex Between the Lactococcus Lactis FPG (Mutm) and a FAPY-dG Containing DNA Descriptor: 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', GLYCEROL, ... Authors: Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B. Deposit date: 2004-05-24 Release date: 2004-09-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase J.Biol.Chem., 279, 2004
6FBU	Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate Descriptor: ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3'), ... Authors: Pomyalov, S, Lansky, S, Golan, G, Zharkov, D.O, Grollman, A.P, Shoham, G. Deposit date: 2017-12-19 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate To Be Published
2OQ4	Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate Descriptor: 5'-D(*C*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(*G*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*GP*G)-3', Endonuclease VIII, ... Authors: Golan, G, Zharkov, D.O, Grollman, A.P, Shoahm, G. Deposit date: 2007-01-31 Release date: 2008-02-26 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrates and mutations of critical residues To be Published
2OPF	Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (R252A) in complex with AP-site containing DNA substrate Descriptor: 5'-D(*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', Endonuclease VIII, ... Authors: Golan, G, Zharov, D.O, Grollman, A.P, Shoham, G. Deposit date: 2007-01-29 Release date: 2008-02-26 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrates and mutations of critical residues To be Published
1XC8	CRYSTAL STRUCTURE COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND A FAPY-DG CONTAINING DNA Descriptor: 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ... Authors: Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B. Deposit date: 2004-09-01 Release date: 2005-09-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase. J.Biol.Chem., 279, 2004
6H0S	Crystal structure of the complex between the Lactococcus lactis FPG mutant G226P and a Fapy-dG containing DNA Descriptor: DNA (5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ... Authors: Coste, F, Castaing, B, Carell, T. Deposit date: 2018-07-10 Release date: 2019-07-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of the complex between the Lactococcus lactis FPG mutant G226P and a Fapy-dG containing DNA To Be Published
4G4O	MutM containing M77A mutation bound to oxoG-containing DNA Descriptor: DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... Authors: Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. Deposit date: 2012-07-16 Release date: 2013-02-20 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM. J.Biol.Chem., 288, 2013
4G4R	MutM containing F114A mutation bound to oxoG-containing DNA Descriptor: DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... Authors: Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. Deposit date: 2012-07-16 Release date: 2013-02-20 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM. J.Biol.Chem., 288, 2013
4G4N	MutM containing M77A mutation bound to undamaged DNA Descriptor: DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... Authors: Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. Deposit date: 2012-07-16 Release date: 2013-02-20 Last modified: 2013-11-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM. J.Biol.Chem., 288, 2013
4G4Q	MutM containing F114A mutation bound to undamaged DNA Descriptor: DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... Authors: Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. Deposit date: 2012-07-16 Release date: 2013-02-20 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM. J.Biol.Chem., 288, 2013
2F5N	MutM crosslinked to undamaged DNA sampling A:T base pair IC1 Descriptor: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', GLYCEROL, ... Authors: Banerjee, A, Santos, W.L, Verdine, G.L. Deposit date: 2005-11-26 Release date: 2006-03-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
2F5S	Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC1 Descriptor: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*(8OG)P*AP*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... Authors: Banerjee, A, Santos, W.L, Verdine, G.L. Deposit date: 2005-11-26 Release date: 2006-03-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
2F5O	MutM crosslinked to undamaged DNA sampling G:C base pair IC3 Descriptor: 5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*GP*GP*AP*TP*CP*TP*AP*CP*C)-3', GLYCEROL, ... Authors: Banerjee, A, Santos, W.L, Verdine, G.L. Deposit date: 2005-11-26 Release date: 2006-03-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
2F5Q	Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC2 Descriptor: 5'-D(*AP*GP*G*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*G*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... Authors: Banerjee, A, Santos, W.L, Verdine, G.L. Deposit date: 2005-11-26 Release date: 2006-03-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
2F5P	MutM crosslinked to undamaged DNA sampling A:T base pair IC2 Descriptor: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*G*TP*CP*CP*AP*AP*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... Authors: Banerjee, A, Santos, W.L, Verdine, G.L. Deposit date: 2005-11-26 Release date: 2006-03-07 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of a DNA glycosylase searching for lesions. Science, 311, 2006

 

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