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1IYJ
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BU of 1iyj by Molmil
STRUCTURE OF A BRCA2-DSS1 COMPLEX
Descriptor: Deleted in split hand/split foot protein 1, breast cancer susceptibility
Authors:Pavletich, N.P, Jeffrey, P.D, Yang, H.J.
Deposit date:2002-08-28
Release date:2002-10-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
1MIU
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BU of 1miu by Molmil
Structure of a BRCA2-DSS1 complex
Descriptor: Breast Cancer type 2 susceptibility protein, Deleted in split hand/split foot protein 1, MERCURY (II) ION
Authors:Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P.
Deposit date:2002-08-23
Release date:2002-09-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
Science, 297, 2002
1MJE
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BU of 1mje by Molmil
STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX
Descriptor: 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2
Authors:Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P.
Deposit date:2002-08-27
Release date:2002-09-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
5WVK
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BU of 5wvk by Molmil
Yeast proteasome-ADP-AlFx
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Ding, Z, Cong, Y.
Deposit date:2016-12-25
Release date:2017-03-22
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx
Cell Res., 27, 2017
4TRQ
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BU of 4trq by Molmil
Crystal structure of Sac3/Thp1/Sem1
Descriptor: 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ...
Authors:Hellerschmied, D, Schneider, S, Kohler, A, Clausen, T.
Deposit date:2014-06-17
Release date:2015-08-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression.
Cell, 162, 2015
8CVT
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BU of 8cvt by Molmil
Human 19S-20S proteasome, state SD2
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Zhao, J.
Deposit date:2022-05-18
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7QO5
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BU of 7qo5 by Molmil
26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
Authors:Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
Deposit date:2021-12-23
Release date:2022-03-16
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
5A5B
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BU of 5a5b by Molmil
Structure of the 26S proteasome-Ubp6 complex
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F.
Deposit date:2015-06-17
Release date:2015-07-22
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5G5P
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BU of 5g5p by Molmil
Structure of the Saccharomyces cerevisiae TREX-2 complex
Descriptor: 26S PROTEASOME COMPLEX SUBUNIT SEM1, NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEAR MRNA EXPORT PROTEIN THP1
Authors:Aibara, S, Bai, X.C, Stewart, M.
Deposit date:2016-05-26
Release date:2016-11-23
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:The Sac3 Tpr-Like Region in the Saccharomyces Cerevisiae Trex-2 Complex is More Extensive But Independent of the Cid Region
J.Struct.Biol., 195, 2016
5GJQ
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BU of 5gjq by Molmil
Structure of the human 26S proteasome bound to USP14-UbAl
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-08-17
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
5GJR
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BU of 5gjr by Molmil
An atomic structure of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-13
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6WJN
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BU of 6wjn by Molmil
SD-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-14
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
3T5X
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BU of 3t5x by Molmil
PCID2:DSS1 Structure
Descriptor: 26S proteasome complex subunit DSS1, PCI domain-containing protein 2
Authors:Stewart, M, Ellisdon, A.M.
Deposit date:2011-07-28
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.123 Å)
Cite:Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex.
Nat.Struct.Mol.Biol., 19, 2012
3T5V
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BU of 3t5v by Molmil
Sac3:Thp1:Sem1 complex
Descriptor: 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1
Authors:Stewart, M, Ellisdon, A.M.
Deposit date:2011-07-28
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex.
Nat.Struct.Mol.Biol., 19, 2012
7EWF
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BU of 7ewf by Molmil
Selenomethionine-substituted structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
Authors:Kuang, Z, Niu, L.
Deposit date:2021-05-25
Release date:2022-09-07
Last modified:2023-04-05
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
7EWM
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BU of 7ewm by Molmil
Native crystal structure of S. cerevisiae Csn12 in complex with Thp3 and Sem1
Descriptor: 26S proteasome complex subunit SEM1, Cop9 signalosome complex subunit 12, Protein THP3
Authors:Kuang, Z, Niu, L.
Deposit date:2021-05-25
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural assembly of the nucleic-acid-binding Thp3-Csn12-Sem1 complex functioning in mRNA splicing.
Nucleic Acids Res., 50, 2022
4CR2
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BU of 4cr2 by Molmil
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CR3
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BU of 4cr3 by Molmil
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CR4
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BU of 4cr4 by Molmil
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JCK
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BU of 3jck by Molmil
Structure of the yeast 26S proteasome lid sub-complex
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit RPN3, ...
Authors:Herzik Jr, M.A, Dambacher, C.M, Worden, E.J, Martin, A, Lander, G.C.
Deposit date:2015-12-20
Release date:2016-01-20
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition.
Elife, 5, 2016
3JCO
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BU of 3jco by Molmil
Structure of yeast 26S proteasome in M1 state derived from Titan dataset
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
3JCP
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BU of 3jcp by Molmil
Structure of yeast 26S proteasome in M2 state derived from Titan dataset
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
6EPC
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BU of 6epc by Molmil
Ground state 26S proteasome (GS2)
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
Authors:Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (12.3 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
6EPD
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BU of 6epd by Molmil
Substrate processing state 26S proteasome (SPS1)
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
Authors:Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
Deposit date:2017-10-11
Release date:2018-02-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (15.4 Å)
Cite:In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018

 

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