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4RGW
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BU of 4rgw by Molmil
Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID
Descriptor: GLYCEROL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7
Authors:Wang, H, Curran, E.C, Hinds, T.R, Wang, E.H, Zheng, N.
Deposit date:2014-09-30
Release date:2014-12-03
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell Res., 24, 2014
4OY2
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BU of 4oy2 by Molmil
Crystal structure of TAF1-TAF7, a TFIID subcomplex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7, ...
Authors:Bhattacharya, S, Lou, X, Rajashankar, K, Jacobson, R.H, Webb, P.
Deposit date:2014-02-10
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Proc.Natl.Acad.Sci.USA, 111, 2014
5FUR
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BU of 5fur by Molmil
Structure of human TFIID-IIA bound to core promoter DNA
Descriptor: SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ...
Authors:Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E.
Deposit date:2016-01-29
Release date:2016-04-06
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
8GXQ
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BU of 8gxq by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
Deposit date:2022-09-21
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (5.04 Å)
Cite:Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8GXS
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BU of 8gxs by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X.
Deposit date:2022-09-21
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
6MZM
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BU of 6mzm by Molmil
Human TFIID bound to promoter DNA and TFIIA
Descriptor: SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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BU of 6mzl by Molmil
Human TFIID canonical state
Descriptor: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
Authors:Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
8WAL
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BU of 8wal by Molmil
Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (8.52 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAK
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BU of 8wak by Molmil
Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (5.47 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAS
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BU of 8was by Molmil
Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.13 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAO
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BU of 8wao by Molmil
Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAQ
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BU of 8waq by Molmil
Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.29 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAP
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BU of 8wap by Molmil
Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (5.85 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAN
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BU of 8wan by Molmil
Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.07 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAR
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BU of 8war by Molmil
Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
7EDX
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BU of 7edx by Molmil
p53-bound TFIID-based core PIC on HDM2 promoter
Descriptor: DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-17
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG9
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BU of 7eg9 by Molmil
TFIID-based intermediate PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG7
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BU of 7eg7 by Molmil
TFIID-based core PIC on SCP promoter
Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EG8
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BU of 7eg8 by Molmil
TFIID-based core PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGA
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BU of 7ega by Molmil
TFIID-based intermediate PIC on PUMA promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGH
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BU of 7egh by Molmil
TFIID lobe C subcomplex
Descriptor: DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGI
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BU of 7egi by Molmil
TFIID in rearranged conformation
Descriptor: TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (9.82 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGD
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BU of 7egd by Molmil
SCP promoter-bound TFIID-TFIIA in initial TBP-loading state
Descriptor: DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (6.75 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGB
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BU of 7egb by Molmil
TFIID-based holo PIC on SCP promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGJ
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BU of 7egj by Molmil
SCP promoter-bound TFIID-TFIIA in post TBP-loading state
Descriptor: DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
Authors:Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (8.64 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021

 

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