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1AR1
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BU of 1ar1 by Molmil
Structure at 2.7 Angstrom Resolution of the Paracoccus Denitrificans two-subunit Cytochrome C Oxidase Complexed with an Antibody Fv Fragment
Descriptor: ANTIBODY FV FRAGMENT, CALCIUM ION, COPPER (II) ION, ...
Authors:Ostermeier, C, Harrenga, A, Ermler, U, Michel, H.
Deposit date:1997-08-08
Release date:1998-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment.
Proc.Natl.Acad.Sci.USA, 94, 1997
6CI0
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BU of 6ci0 by Molmil
Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with E101A (II) mutation
Descriptor: (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ...
Authors:Liu, J, Hiser, C, Ferguson-Miller, S.
Deposit date:2018-02-23
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain.
Biochim. Biophys. Acta, 1859, 2018
2GSM
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BU of 2gsm by Molmil
Catalytic Core (Subunits I and II) of Cytochrome c oxidase from Rhodobacter sphaeroides
Descriptor: CADMIUM ION, CALCIUM ION, COPPER (II) ION, ...
Authors:Qin, L, Hiser, C, Mulichak, A, Garavito, R.M, Ferguson-Miller, S.
Deposit date:2006-04-26
Release date:2006-10-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
5LUF
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BU of 5luf by Molmil
Cryo-EM of bovine respirasome
Descriptor: COPPER (II) ION, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
Authors:Sousa, J.S, Mills, D.J, Vonck, J, Kuehlbrandt, W.
Deposit date:2016-09-08
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Functional asymmetry and electron flow in the bovine respirasome.
Elife, 5, 2016
2OCC
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BU of 2occ by Molmil
BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE
Descriptor: COPPER (II) ION, CYTOCHROME C OXIDASE, HEME-A, ...
Authors:Tsukihara, T, Yao, M.
Deposit date:1998-05-26
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase.
Science, 280, 1998
3FYE
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BU of 3fye by Molmil
Catalytic core subunits (I and II) of cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state
Descriptor: CADMIUM ION, CALCIUM ION, COPPER (I) ION, ...
Authors:Qin, L, Mills, D.A, Proshlyakov, D.A, Hiser, C, Ferguson-Miller, S.
Deposit date:2009-01-22
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake.
Biochemistry, 48, 2009
6T0B
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BU of 6t0b by Molmil
The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-02
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T15
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BU of 6t15 by Molmil
The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CARDIOLIPIN, COPPER (II) ION, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-03
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PW1
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BU of 6pw1 by Molmil
Cytochrome c Oxidase delta 16
Descriptor: (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ...
Authors:Liu, J, Ferguson-Miller, S.
Deposit date:2019-07-21
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry.
Biochim Biophys Acta Bioenerg, 1861, 2019
6PW0
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BU of 6pw0 by Molmil
Cytochrome C oxidase delta 6 mutant
Descriptor: (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ...
Authors:Liu, J, Ferguson-Miller, S.
Deposit date:2019-07-21
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry.
Biochim Biophys Acta Bioenerg, 1861, 2019
3HB3
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BU of 3hb3 by Molmil
High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase
Descriptor: ANTIBODY FV FRAGMENT, CALCIUM ION, COPPER (I) ION, ...
Authors:Koepke, J, Angerer, H, Peng, G.
Deposit date:2009-05-04
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways
Biochim.Biophys.Acta, 1787, 2009
1V55
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BU of 1v55 by Molmil
Bovine heart cytochrome c oxidase at the fully reduced state
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Tsukihara, T, Shimokata, K, Katayama, Y, Shimada, H, Muramoto, K, Aoyama, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Yao, M, Ishimura, Y, Yoshikawa, S.
Deposit date:2003-11-21
Release date:2003-12-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process.
Proc.Natl.Acad.Sci.Usa, 100, 2003
6YMY
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BU of 6ymy by Molmil
Cytochrome c oxidase from Saccharomyces cerevisiae
Descriptor: (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, COPPER (II) ION, ...
Authors:Berndtsson, J, Rathore, S, Ott, M.
Deposit date:2020-04-10
Release date:2020-09-09
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance.
Embo Rep., 21, 2020
1V54
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BU of 1v54 by Molmil
Bovine heart cytochrome c oxidase at the fully oxidized state
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Tsukihara, T, Shimokata, K, Katayama, Y, Shimada, H, Muramoto, K, Aoyama, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Yao, M, Ishimura, Y, Yoshikawa, S.
Deposit date:2003-11-21
Release date:2003-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process.
Proc.Natl.Acad.Sci.Usa, 100, 2003
6YMX
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BU of 6ymx by Molmil
CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae
Descriptor: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate, (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate, ...
Authors:Berndtsson, J, Rathore, S, Ott, M.
Deposit date:2020-04-10
Release date:2020-09-09
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance.
Embo Rep., 21, 2020
5W97
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BU of 5w97 by Molmil
Crystal Structure of CO-bound Cytochrome c Oxidase determined by Serial Femtosecond X-Ray Crystallography at Room Temperature
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Rousseau, D.L, Yeh, S.-R, Ishigami, I, Zatsepin, N.A, Grant, T.D, Fromme, P, Fromme, R.
Deposit date:2017-06-22
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WEH
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BU of 5weh by Molmil
Cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Aa3-type cytochrome c oxidase subunit IV, CALCIUM ION, ...
Authors:Liu, J, Ferguson-Miller, F, Ling, Q, Hiser, C.
Deposit date:2017-07-10
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity.
Biochem. Soc. Trans., 45, 2017
1M56
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BU of 1m56 by Molmil
Structure of cytochrome c oxidase from Rhodobactor sphaeroides (Wild Type)
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, COPPER (II) ION, ...
Authors:Svensson-Ek, M, Abramson, J, Larsson, G, Tornroth, S, Brezezinski, P, Iwata, S.
Deposit date:2002-07-08
Release date:2002-08-28
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides.
J.Mol.Biol., 321, 2002
3WG7
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BU of 3wg7 by Molmil
A 1.9 angstrom radiation damage free X-ray structure of large (420KDa) protein by femtosecond crystallography
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Hirata, K, Shinzawa-Itoh, K, Yano, N, Takemura, S, Kato, K, Hatanaka, M, Muramoto, K, Kawahara, T, Tsukihara, T, Yamashita, E, Tono, K, Ueno, G, Hikima, T, Murakami, H, Inubushi, Y, Yabashi, M, Ishikawa, T, Yamamoto, M, Ogura, T, Sugimoto, H, Shen, J.R, Yoshikawa, S, Ago, H.
Deposit date:2013-07-29
Release date:2014-04-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determination of damage-free crystal structure of an X-ray-sensitive protein using an XFEL.
Nat.Methods, 11, 2014
1M57
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BU of 1m57 by Molmil
Structure of cytochrome c oxidase from Rhodobacter sphaeroides (EQ(I-286) mutant))
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, COPPER (II) ION, ...
Authors:Svensson-Ek, M, Abramson, J, Larsson, G, Tornroth, S, Brezezinski, P, Iwata, S.
Deposit date:2002-07-08
Release date:2002-08-28
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides.
J.Mol.Biol., 321, 2002
3X2Q
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BU of 3x2q by Molmil
X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state at 2.0 angstrom resolution
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Yano, N, Muramoto, K, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Yoshikawa, S, Tsukihara, T.
Deposit date:2014-12-26
Release date:2015-06-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state at 2.0 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 71, 2015
5B3S
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BU of 5b3s by Molmil
Bovine heart cytochrome c oxidase in the carbon monoxide-bound mixed-valence state at 1.68 angstrom resolution (50 K)
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Shinzawa-Ito, K, Yoshikawa, S, Tsukihara, T.
Deposit date:2016-03-11
Release date:2017-03-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Bovine heart cytochrome c oxidase in the carbon monoxide-bound mixed-valence state at 1.68 angstrom resolution (50 K)
To Be Published
5B1B
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BU of 5b1b by Molmil
Bovine heart cytochrome c oxidase in the fully reduced state at 1.6 angstrom resolution
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Yano, N, Muramoto, K, Shimada, A, Takemura, S, Baba, J, Fujisawa, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Tsukihara, T, Yoshikawa, S.
Deposit date:2015-12-01
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Mg2+-containing Water Cluster of Mammalian Cytochrome c Oxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle.
J.Biol.Chem., 291, 2016
5B1A
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BU of 5b1a by Molmil
Bovine heart cytochrome c oxidase in the fully oxidized state at 1.5 angstrom resolution
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Yano, N, Muramoto, K, Shimada, A, Takemura, S, Baba, J, Fujisawa, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Tsukihara, T, Yoshikawa, S.
Deposit date:2015-12-01
Release date:2016-09-14
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Mg2+-containing Water Cluster of Mammalian Cytochrome c Oxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle.
J.Biol.Chem., 291, 2016
7O3C
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BU of 7o3c by Molmil
Murine supercomplex CIII2CIV in the mature unlocked conformation
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
Authors:Vercellino, I, Sazanov, L.A.
Deposit date:2021-04-01
Release date:2021-10-13
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
Nature, 598, 2021

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