Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2IPX
DownloadVisualize
BU of 2ipx by Molmil
Human Fibrillarin
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, CALCIUM ION, rRNA 2'-O-methyltransferase fibrillarin
Authors:Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-10-12
Release date:2006-10-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of Human Fibrillarin in complex with SAH
To be Published
1PRY
DownloadVisualize
BU of 1pry by Molmil
Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)
Descriptor: Fibrillarin-like pre-rRNA processing protein
Authors:Deng, L, Starostina, N.G, Liu, Z.-J, Rose, J.P, Terns, R.M, Terns, M.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-06-20
Release date:2004-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus
Biochem.Biophys.Res.Commun., 315, 2004
4DF3
DownloadVisualize
BU of 4df3 by Molmil
Crystal Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-L-methionine at 1.7A
Descriptor: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, S-ADENOSYLMETHIONINE
Authors:de Silva, U.
Deposit date:2012-01-22
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-L-methionine at 1.7 A resolution.
Acta Crystallogr.,Sect.F, 68, 2012
1FBN
DownloadVisualize
BU of 1fbn by Molmil
CRYSTAL STRUCTURE OF A FIBRILLARIN HOMOLOGUE FROM METHANOCOCCUS JANNASCHII, A HYPERTHERMOPHILE, AT 1.6 A
Descriptor: MJ FIBRILLARIN HOMOLOGUE
Authors:Wang, H, Boisvert, D, Kim, K.K, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:1999-04-25
Release date:2000-04-26
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.
EMBO J., 19, 2000
1G8S
DownloadVisualize
BU of 1g8s by Molmil
METHANOCOCCUS JANNASCHII FIBRILLARIN PRE-RRNA PROCESSING PROTEIN
Descriptor: FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN, METHIONINE
Authors:Boisvert, D.C, Kim, S.H.
Deposit date:2000-11-20
Release date:2003-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Structural Approach to Gene Function and Structure Quality for Pyrococcus horikshii Fibrillarin
To be Published
1G8A
DownloadVisualize
BU of 1g8a by Molmil
PYROCOCCUS HORIKOSHII FIBRILLARIN PRE-RRNA PROCESSING PROTEIN
Descriptor: FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN
Authors:Boisvert, D.C, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2000-11-16
Release date:2003-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Structural Approach to Gene Function and Structure Quality for Pyrococcus horikoshii Fibrillarin
To be Published
7SE7
DownloadVisualize
BU of 7se7 by Molmil
Crystal structure of human Fibrillarin in complex with S-adenosyl-L-methionine
Descriptor: S-ADENOSYLMETHIONINE, rRNA 2'-O-methyltransferase fibrillarin
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SEC
DownloadVisualize
BU of 7sec by Molmil
Crystal structure of human Fibrillarin in complex with compound 1a
Descriptor: 2-[(8S)-4-oxo-2-(trifluoromethyl)-4,5-dihydropyrazolo[1,5-a]pyrazin-6-yl]acetamide, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SE6
DownloadVisualize
BU of 7se6 by Molmil
Crystal structure of human Fibrillarin in ligand-free state
Descriptor: FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SEB
DownloadVisualize
BU of 7seb by Molmil
Crystal structure of human Fibrillarin in complex with compound 2 from single soak
Descriptor: 6-(trifluoromethyl)pyrimidin-4-amine, FORMIC ACID, rRNA 2'-O-methyltransferase fibrillarin
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SE9
DownloadVisualize
BU of 7se9 by Molmil
Crystal structure of human Fibrillarin in complex with compound 1 from single soak
Descriptor: (5S)-3-methyl-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazin-1(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SED
DownloadVisualize
BU of 7sed by Molmil
Crystal structure of human Fibrillarin in complex with compound 2a
Descriptor: FORMIC ACID, N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine, rRNA 2'-O-methyltransferase fibrillarin
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SEA
DownloadVisualize
BU of 7sea by Molmil
Crystal structure of human Fibrillarin in complex with compound 2 from cocktail soak
Descriptor: 6-(trifluoromethyl)pyrimidin-4-amine, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
7SE8
DownloadVisualize
BU of 7se8 by Molmil
Crystal structure of human Fibrillarin in complex with fragment 1 from cocktail soak
Descriptor: (5S)-3-methyl-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazin-1(2H)-one, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Shi, Y, El-Deeb, I.M, Masic, V, Hartley-Tassell, L, Maggioni, A, von Itzstein, M, Ve, T.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin.
Pharmaceuticals, 15, 2021
2NNW
DownloadVisualize
BU of 2nnw by Molmil
Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs
Descriptor: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein
Authors:Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H.
Deposit date:2006-10-24
Release date:2007-08-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.
J.Mol.Biol., 371, 2007
6ZDT
DownloadVisualize
BU of 6zdt by Molmil
Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain
Descriptor: Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin
Authors:Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W.
Deposit date:2020-06-15
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Rna, 27, 2021
7XPL
DownloadVisualize
BU of 7xpl by Molmil
Crystal structure of a C/D-free RNA-guided RNA 2'-O-methyltransferase
Descriptor: BMG3 RNA strand A, BMG3 RNA strand B, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ...
Authors:Wang, J, Ye, K.
Deposit date:2022-05-04
Release date:2022-10-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.213 Å)
Cite:Methylation guide RNAs without box C/D motifs.
Rna, 28, 2022
1NT2
DownloadVisualize
BU of 1nt2 by Molmil
CRYSTAL STRUCTURE OF FIBRILLARIN/NOP5P COMPLEX
Descriptor: Fibrillarin-like pre-rRNA processing protein, S-ADENOSYLMETHIONINE, conserved hypothetical protein
Authors:Aittaleb, M, Rashid, R, Chen, Q, Palmer, J.R, Daniels, C.J, Li, H.
Deposit date:2003-01-28
Release date:2003-04-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and function of archaeal box C/D sRNP core proteins.
Nat.Struct.Biol., 10, 2003
3ID6
DownloadVisualize
BU of 3id6 by Molmil
Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex
Descriptor: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, Pre mRNA splicing protein, S-ADENOSYLMETHIONINE
Authors:Ye, K.
Deposit date:2009-07-20
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural organization of box C/D RNA-guided RNA methyltransferase.
Proc.Natl.Acad.Sci.USA, 106, 2009
3NVM
DownloadVisualize
BU of 3nvm by Molmil
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle
Descriptor: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein
Authors:Xue, S, Wang, R, Li, H.
Deposit date:2010-07-08
Release date:2011-07-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.408 Å)
Cite:Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle.
Mol.Cell, 39, 2010
5OQL
DownloadVisualize
BU of 5oql by Molmil
Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum
Descriptor: 35S rRNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ...
Authors:Cheng, J, Kellner, N, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2017-08-12
Release date:2017-10-11
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017
4BY9
DownloadVisualize
BU of 4by9 by Molmil
The structure of the Box CD enzyme reveals regulation of rRNA methylation
Descriptor: 5'-R(*UP*CP*GP*CP*CP*CP*AP*UP*CP*AP*CP)-3', 50S RIBOSOMAL PROTEIN L7AE, FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERASE, ...
Authors:Lapinaite, A, Simon, B, Skjaerven, L, Rakwalska-Bange, M, Gabel, F, Carlomagno, T.
Deposit date:2013-07-18
Release date:2013-10-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
Nature, 502, 2013
3ID5
DownloadVisualize
BU of 3id5 by Molmil
Crystal structure of Sulfolobus solfataricus C/D RNP assembled with Nop5, fibrillarin, L7Ae and a split half C/D RNA
Descriptor: 50S ribosomal protein L7Ae, Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, Pre mRNA splicing protein, ...
Authors:Ye, K.
Deposit date:2009-07-20
Release date:2009-08-25
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (4.01 Å)
Cite:Structural organization of box C/D RNA-guided RNA methyltransferase.
Proc.Natl.Acad.Sci.USA, 106, 2009
5WLC
DownloadVisualize
BU of 5wlc by Molmil
The complete structure of the small subunit processome
Descriptor: 18S pre-rRNA, 5' ETS, Bms1, ...
Authors:Barandun, J, Chaker-Margot, M, Hunziker, M, Klinge, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The complete structure of the small-subunit processome.
Nat. Struct. Mol. Biol., 24, 2017
5WYJ
DownloadVisualize
BU of 5wyj by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon