5GTJ
 
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7EZN
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5BX1
 | | Crystal Structure of PRL-1 complex with compound analogy 3 | | Descriptor: | 3-(5,6-dimethyl-2H-isoindol-2-yl)-N'-[(E)-furan-2-ylmethylidene]benzohydrazide, Protein tyrosine phosphatase type IVA 1, SULFATE ION | | Authors: | Liu, S, Bai, Y, Zhang, Z. | | Deposit date: | 2015-06-08 | | Release date: | 2016-12-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of PRL-1 complex with compound analogy 3
To Be Published
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7NCY
 | | Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3 | | Descriptor: | Dual specificity phosphatase, GLYCEROL, NICKEL (II) ION | | Authors: | Welin, M, Akutsu, M, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Nordberg Karlsson, E. | | Deposit date: | 2021-01-29 | | Release date: | 2022-03-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3
To Be Published
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7C8S
 | | Crystal structure of DUSP22 mutant_N128A | | Descriptor: | Dual specificity protein phosphatase 22, SULFATE ION | | Authors: | Lai, C.H, Lyu, P.C. | | Deposit date: | 2020-06-03 | | Release date: | 2020-10-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
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8GZ4
 | | Crystal structure of MPXV phosphatase | | Descriptor: | Dual specificity protein phosphatase H1, PHOSPHATE ION | | Authors: | Yang, H.T, Wang, W, Huang, H.J, Ji, X.Y. | | Deposit date: | 2022-09-25 | | Release date: | 2023-05-17 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | Crystal structure of monkeypox H1 phosphatase, an antiviral drug target.
Protein Cell, 14, 2023
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3LJ8
 | | Crystal Structure of MKP-4 | | Descriptor: | Tyrosine-protein phosphatase | | Authors: | Jeong, D.G, Yoon, T.S, Jung, S.-K, Park, H.S, Ryu, S.E, Kim, S.J. | | Deposit date: | 2010-01-26 | | Release date: | 2010-12-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
Acta Crystallogr.,Sect.D, 67, 2011
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2WGP
 | | Crystal structure of human dual specificity phosphatase 14 | | Descriptor: | DUAL SPECIFICITY PROTEIN PHOSPHATASE 14, PHOSPHATE ION | | Authors: | Lountos, G.T, Tropea, J.E, Cherry, S, Waugh, D.S. | | Deposit date: | 2009-04-22 | | Release date: | 2009-10-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Overproduction, Purification and Structure Determination of Human Dual-Specificity Phosphatase 14.
Acta Crystallogr.,Sect.D, 65, 2009
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2Y96
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4WOH
 | | Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate | | Descriptor: | 1,2-ETHANEDIOL, 4-NITROPHENYL PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Lountos, G.T, Cherry, S, Tropea, J.E, Waugh, D.S. | | Deposit date: | 2014-10-15 | | Release date: | 2015-02-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.
Acta Crystallogr.,Sect.F, 71, 2015
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4Y2E
 | | Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S) | | Descriptor: | Dual specificity protein phosphatase 7, PHOSPHATE ION | | Authors: | Lountos, G.T, Austin, B.P, Tropea, J.E, Waugh, D.S. | | Deposit date: | 2015-02-09 | | Release date: | 2015-06-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structure of human dual-specificity phosphatase 7, a potential cancer drug target.
Acta Crystallogr.,Sect.F, 71, 2015
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4R30
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3RGQ
 | | Crystal Structure of PTPMT1 in complex with PI(5)P | | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Protein-tyrosine phosphatase mitochondrial 1 | | Authors: | Xiao, J, Engel, J.L. | | Deposit date: | 2011-04-08 | | Release date: | 2011-07-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3RGO
 | | Crystal Structure of PTPMT1 | | Descriptor: | Protein-tyrosine phosphatase mitochondrial 1, SULFATE ION | | Authors: | Xiao, J, Engel, J.L. | | Deposit date: | 2011-04-08 | | Release date: | 2011-07-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.928 Å) | | Cite: | Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4KYR
 | | Structure of a product bound plant phosphatase | | Descriptor: | PHOSPHATE ION, Phosphoglucan phosphatase LSF2, chloroplastic, ... | | Authors: | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | | Deposit date: | 2013-05-29 | | Release date: | 2013-07-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation.
Plant Cell, 25, 2013
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4KYQ
 | | Structure of a product bound plant phosphatase | | Descriptor: | CITRATE ANION, Phosphoglucan phosphatase LSF2, chloroplastic | | Authors: | Meekins, D.A, Guo, H.-F, Husodo, S, Paasch, B.C, Bridges, T.M, Santelia, D, Kotting, O, Vander Kooi, C.W, Gentry, M.S. | | Deposit date: | 2013-05-29 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structure of the Arabidopsis Glucan Phosphatase LIKE SEX FOUR2 Reveals a Unique Mechanism for Starch Dephosphorylation.
Plant Cell, 25, 2013
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3RZ2
 | | Crystal of Prl-1 complexed with peptide | | Descriptor: | Prl-1 (PTP4A1), Protein tyrosine phosphatase type IVA 1 | | Authors: | Zhang, Z.-Y, Liu, D, Bai, Y. | | Deposit date: | 2011-05-11 | | Release date: | 2011-10-26 | | Last modified: | 2014-10-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J.Biol.Chem., 286, 2011
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3S4E
 | | Crystal Structrue of a Novel Mitogen-activated Protein Kinase Phosphatase, SKRP1 | | Descriptor: | Dual specificity protein phosphatase 19, PHOSPHATE ION, SULFATE ION | | Authors: | Wei, C.H, Ryu, S.Y, Jeon, Y.H, Jeong, D.G, Kim, S.J, Ryu, S.E. | | Deposit date: | 2011-05-19 | | Release date: | 2012-04-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Crystal structure of a novel mitogen-activated protein kinase phosphatase, SKRP1.
Proteins, 79, 2011
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4MBB
 | | Cubic crystal form of PIR1 dual specificity phosphatase core | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | | Authors: | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | | Deposit date: | 2013-08-19 | | Release date: | 2013-12-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.849 Å) | | Cite: | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
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4B04
 | | Crystal structure of the Catalytic Domain of Human DUSP26 (C152S) | | Descriptor: | DUAL SPECIFICITY PROTEIN PHOSPHATASE 26 | | Authors: | Won, E.-Y, Lee, D.Y, Park, S.G, Yokoyama, S, Kim, S.J, Chi, S.-W. | | Deposit date: | 2012-06-28 | | Release date: | 2013-05-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.205 Å) | | Cite: | High-Resolution Crystal Structure of the Catalytic Domain of Human Dual-Specificity Phosphatase 26
Acta Crystallogr.,Sect.D, 69, 2013
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5M43
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7Y4E
 | | Crystal structure of DUSP10 mutant_N130A | | Descriptor: | Dual specificity protein phosphatase 10 | | Authors: | Hu, I.C, Lyu, P.C. | | Deposit date: | 2022-06-14 | | Release date: | 2023-06-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Crystal structure of DUSP10 mutant_N130A
To Be Published
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7Y4D
 | | Crystal structure of DUSP10 mutant_S95A | | Descriptor: | Dual specificity protein phosphatase 10 | | Authors: | Hu, I.C, Lyu, P.C. | | Deposit date: | 2022-06-14 | | Release date: | 2023-06-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Crystal structure of DUSP10 mutant_S95A
To Be Published
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7Y4B
 | | Crystal structure of DUSP10 mutant_D59A | | Descriptor: | Dual specificity protein phosphatase 10 | | Authors: | Hu, I.C, Lyu, P.C. | | Deposit date: | 2022-06-14 | | Release date: | 2023-06-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal structure of DUSP10 mutant_D59A
To Be Published
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7Y4C
 | | Crystal structure of DUSP10 | | Descriptor: | Dual specificity protein phosphatase 10 | | Authors: | Hu, I.C, Lyu, P.C. | | Deposit date: | 2022-06-14 | | Release date: | 2023-06-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Crystal structure of DUSP10
To Be Published
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