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1N1F
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Crystal Structure of Human Interleukin-19
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, interleukin-19
Authors:Chang, C, Magracheva, E, Kozlov, S, Fong, S, Tobin, G, Kotenko, S, Wlodawer, A, Zdanov, A.
Deposit date:2002-10-17
Release date:2003-02-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of interleukin-19 defines a new subfamily of helical cytokines
J.Biol.Chem., 278, 2003
4X51
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BU of 4x51 by Molmil
X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y
Descriptor: Interleukin-10
Authors:Kuenze, G.
Deposit date:2014-12-04
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y
To Be Published
2H24
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Crystal structure of human IL-10
Descriptor: Interleukin-10
Authors:Yoon, S.I, Walter, M.R.
Deposit date:2006-05-18
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.
J.Biol.Chem., 281, 2006
2ILK
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CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN-10 AT 1.6 ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-10, SULFATE ION
Authors:Zdanov, A, Schalk-Hihi, C, Wlodawer, A.
Deposit date:1996-07-01
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of human interleukin-10 at 1.6 A resolution and a model of a complex with its soluble receptor.
Protein Sci., 5, 1996
1VLK
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BU of 1vlk by Molmil
STRUCTURE OF VIRAL INTERLEUKIN-10
Descriptor: VIRAL INTERLEUKIN-10
Authors:Zdanov, A, Schalk-Hihi, C, Wlodawer, A.
Deposit date:1997-02-14
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Epstein-Barr virus protein BCRF1, a homolog of cellular interleukin-10.
J.Mol.Biol., 268, 1997
1ILK
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INTERLEUKIN-10 CRYSTAL STRUCTURE REVEALS THE FUNCTIONAL DIMER WITH AN UNEXPECTED TOPOLOGICAL SIMILARITY TO INTERFERON GAMMA
Descriptor: INTERLEUKIN-10
Authors:Zdanov, A, Schalk-Hihi, C, Gustchina, A, Wlodawer, A.
Deposit date:1995-04-21
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma.
Structure, 3, 1995
1INR
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BU of 1inr by Molmil
CYTOKINE SYNTHESIS
Descriptor: INTERLEUKIN-10
Authors:Walter, M.R.
Deposit date:1995-07-31
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of interleukin 10 reveals an interferon gamma-like fold.
Biochemistry, 34, 1995
6X93
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BU of 6x93 by Molmil
Interleukin-10 signaling complex with IL-10RA and IL-10RB
Descriptor: Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta
Authors:Saxton, R.A, Tsutsumi, N, Gati, C, Garcia, K.C.
Deposit date:2020-06-02
Release date:2021-03-17
Last modified:2021-03-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.
Science, 371, 2021
4DOH
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BU of 4doh by Molmil
IL20/IL201/IL20R2 Ternary Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-20, Interleukin-20 receptor subunit alpha, ...
Authors:Logsdon, N.J, Walter, M.R.
Deposit date:2012-02-09
Release date:2012-07-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.
Proc.Natl.Acad.Sci.USA, 109, 2012
1Y6M
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BU of 1y6m by Molmil
Crystal structure of Epstein-Barr virus IL-10 complexed with the soluble IL-10R1 chain
Descriptor: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
Authors:Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
Deposit date:2004-12-06
Release date:2005-05-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1Y6K
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Crystal structure of human IL-10 complexed with the soluble IL-10R1 chain
Descriptor: Interleukin-10, Interleukin-10 receptor alpha chain
Authors:Yoon, S.I, Jones, B.C, Josepson, K, Logsdon, N.J, Walter, M.R.
Deposit date:2004-12-06
Release date:2005-12-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1Y6N
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Crystal structure of Epstein-Barr virus IL-10 mutant (A87I) complexed with the soluble IL-10R1 chain
Descriptor: Interleukin-10 receptor alpha chain, Viral interleukin-10 homolog
Authors:Yoon, S.I, Jones, B.C, Logsdon, N.J, Walter, M.R.
Deposit date:2004-12-06
Release date:2005-05-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain.
Structure, 13, 2005
1J7V
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BU of 1j7v by Molmil
HUMAN IL-10 / IL-10R1 COMPLEX
Descriptor: INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN
Authors:Josephson, K, Logsdon, N, Walter, M.R.
Deposit date:2001-05-18
Release date:2001-09-19
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.
Immunity, 15, 2001
1LK3
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BU of 1lk3 by Molmil
ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT
Descriptor: 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10
Authors:Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R.
Deposit date:2002-04-23
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography.
Structure, 10, 2002
1LQS
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BU of 1lqs by Molmil
CRYSTAL STRUCTURE OF HUMAN CYTOMEGALOVIRUS IL-10 BOUND TO SOLUBLE HUMAN IL-10R1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN, INTERLEUKIN-10-LIKE PROTEIN
Authors:Jones, B.C, Logsdon, N.J, Josephson, K, Cook, J, Barry, P.A, Walter, M.R.
Deposit date:2002-05-13
Release date:2002-07-17
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1.
Proc.Natl.Acad.Sci.USA, 99, 2002

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