6V2J
 
 | | Crystal structure of ClC-ec1 triple mutant (E113Q, E148Q, E203Q) | | Descriptor: | CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA | | Authors: | Maduke, M, Mathews, I.I, Chavan, T.S. | | Deposit date: | 2019-11-24 | | Release date: | 2020-05-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl - /H + transport cycle.
Elife, 9, 2020
|
|
5HD8
 | |
2R9H
 | |
4LOU
 | |
5TQQ
 | |
5TR1
 | |
1KPK
 | | Crystal Structure of the ClC Chloride Channel from E. coli | | Descriptor: | putative channel transporter | | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-12-31 | | Release date: | 2002-01-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
|
|
1KPL
 | | Crystal Structure of the ClC Chloride Channel from S. typhimurium | | Descriptor: | CHLORIDE ION, N-OCTANE, PENTADECANE, ... | | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-12-31 | | Release date: | 2002-01-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
|
|
7N8P
 | |
7N9W
 | |
4ENE
 | | Structure of the N- and C-terminal trimmed ClC-ec1 Cl-/H+ antiporter and Fab Complex | | Descriptor: | CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, H(+)/Cl(-) exchange transporter ClcA, ... | | Authors: | Lim, H.H, Shane, T, Miller, C. | | Deposit date: | 2012-04-13 | | Release date: | 2012-12-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Intracellular proton access in a cl(-)/h(+) antiporter.
Plos Biol., 10, 2012
|
|
4FG6
 | | Structure of EcCLC E148A mutant in Glutamate | | Descriptor: | Fab fragment (Heavy chain), Fab fragment (Light chain), H(+)/Cl(-) exchange transporter ClcA | | Authors: | Feng, L, MacKinnon, R. | | Deposit date: | 2012-06-04 | | Release date: | 2012-07-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.019 Å) | | Cite: | Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3NMO
 | |
3ND0
 | | X-ray crystal structure of a slow cyanobacterial Cl-/H+ antiporter | | Descriptor: | CHLORIDE ION, Sll0855 protein | | Authors: | Jayaram, H, Robertson, J, Wu, F, Williams, C, Miller, C. | | Deposit date: | 2010-06-06 | | Release date: | 2011-01-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
|
|
6K5F
 | | Crystal structure of the CLC-ec1 deltaNC in presence of 200 mM NaBr | | Descriptor: | BROMIDE ION, Fab fragment, heavy chain, ... | | Authors: | Park, K, Lim, H.H. | | Deposit date: | 2019-05-28 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.203 Å) | | Cite: | Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
3DET
 | | Structure of the E148A, Y445A doubly ungated mutant of E.coli CLC_Ec1, Cl-/H+ antiporter | | Descriptor: | Fab fragment, Heavy chain, Light chain, ... | | Authors: | Jayaram, H, Accardi, A, Wu, F, Williams, C, Miller, C. | | Deposit date: | 2008-06-10 | | Release date: | 2008-06-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
7XF5
 | | Full length human CLC-2 channel in apo state | | Descriptor: | Chloride channel protein 2 | | Authors: | Wang, L. | | Deposit date: | 2022-04-01 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
|
|
7XJA
 | | TMD masked refine map of human ClC-2 | | Descriptor: | Chloride channel protein 2 | | Authors: | Wang, L. | | Deposit date: | 2022-04-15 | | Release date: | 2023-05-17 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
|
|
6K5D
 | |
3Q17
 | | Structure of a slow CLC Cl-/H+ antiporter from a cyanobacterium in Bromide | | Descriptor: | BROMIDE ION, Sll0855 protein | | Authors: | Jayaram, H, Robertson, J.L, Fang, W, Williams, C, Miller, C. | | Deposit date: | 2010-12-16 | | Release date: | 2011-01-19 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium.
Biochemistry, 50, 2011
|
|
3EJY
 | |
6LSC
 | |
6QVD
 | |
6QV6
 | |
6QVB
 | |
