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8AMS
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BU of 8ams by Molmil
Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Polyubiquitin-C, ...
Authors:Perez-Borrajero, C, Kotova, I, Murciano, B, Hennig, J.
Deposit date:2022-08-04
Release date:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biophysical studies of TRIM2 and TRIM3
To Be Published
8AMR
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BU of 8amr by Molmil
Coiled-coil domain of human TRIM3
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Tripartite motif-containing protein 3
Authors:Perez-Borrajero, C, Murciano, B, Hennig, J.
Deposit date:2022-08-04
Release date:2023-11-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural and biophysical studies of TRIM2 and TRIM3
To Be Published
7Y4S
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BU of 7y4s by Molmil
Structure of human MG53 homo-dimer
Descriptor: Tripartite motif-containing protein 72
Authors:Chen, L, Niu, Y.
Deposit date:2022-06-16
Release date:2022-09-21
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of human MG53 homodimer.
Biochem.J., 479, 2022
7XZ0
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BU of 7xz0 by Molmil
TRIM E3 ubiquitin ligase
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Park, S.H, Song, H.K.
Deposit date:2022-06-02
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Nat.Struct.Mol.Biol., 30, 2023
7XZ1
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BU of 7xz1 by Molmil
TRIM E3 ubiquitin ligase
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Park, S.H, Song, H.K.
Deposit date:2022-06-02
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (5.2 Å)
Cite:Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Nat.Struct.Mol.Biol., 30, 2023
7XYY
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BU of 7xyy by Molmil
TRIM E3 ubiquitin ligase WT
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Park, S.H, Song, H.K.
Deposit date:2022-06-02
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (7.1 Å)
Cite:Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Nat.Struct.Mol.Biol., 30, 2023
7XZ2
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BU of 7xz2 by Molmil
TRIM E3 ubiquitin ligase
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Park, S.H, Song, H.K.
Deposit date:2022-06-02
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Nat.Struct.Mol.Biol., 30, 2023
7XYZ
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BU of 7xyz by Molmil
TRIM E3 ubiquitin ligase
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Park, S.H, Song, H.K.
Deposit date:2022-06-02
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (4.62 Å)
Cite:Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Nat.Struct.Mol.Biol., 30, 2023
7XV2
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BU of 7xv2 by Molmil
TRIM E3 ubiquitin ligase
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Park, S.H, Song, H.K.
Deposit date:2022-05-20
Release date:2023-05-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane.
Nat.Struct.Mol.Biol., 30, 2023
7XT2
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BU of 7xt2 by Molmil
Crystal structure of TRIM72
Descriptor: Tripartite motif-containing protein 72, ZINC ION
Authors:Zhou, C, Ma, Y.M, Ding, L.
Deposit date:2022-05-15
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for TRIM72 oligomerization during membrane damage repair
Nat Commun, 14, 2023
7Z36
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BU of 7z36 by Molmil
Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain
Descriptor: Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta, SMARCAD1 CUE1 domain, ZINC ION, ...
Authors:Stoll, G.A, Modis, Y.
Deposit date:2022-03-01
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and functional mapping of the KRAB-KAP1 repressor complex.
Embo J., 41, 2022
7WSJ
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BU of 7wsj by Molmil
Crystal structure of the tandem B-box domain of Arabidopsis thaliana CONSTANS
Descriptor: ZINC ION, Zinc finger protein CONSTANS
Authors:Dahal, P, Pathak, D, Kwon, E, Kim, D.Y.
Deposit date:2022-01-29
Release date:2022-03-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a tandem B-box domain from Arabidopsis CONSTANS.
Biochem.Biophys.Res.Commun., 599, 2022
7VSQ
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BU of 7vsq by Molmil
Crystal strcuture of the tandem B-Box domains of CONSTANS
Descriptor: ZINC ION, Zinc finger protein CONSTANS
Authors:Liu, R, Lv, X, Du, J.
Deposit date:2021-10-27
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation.
J Integr Plant Biol, 64, 2022
7VSP
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BU of 7vsp by Molmil
Crystal strcuture of the tandem B-Box domains of COL2
Descriptor: ZINC ION, Zinc finger protein CONSTANS-LIKE 2
Authors:Lv, X, Liu, R, Du, J.
Deposit date:2021-10-27
Release date:2022-03-02
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation.
J Integr Plant Biol, 64, 2022
6O5K
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BU of 6o5k by Molmil
Murine TRIM28 Bbox1 domain
Descriptor: Transcription intermediary factor 1-beta, ZINC ION
Authors:Sun, Y, Keown, J.R, Goldstone, D.C.
Deposit date:2019-03-03
Release date:2019-06-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
J.Mol.Biol., 431, 2019
6QU1
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BU of 6qu1 by Molmil
Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom resolution.
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta,Transcription intermediary factor 1-beta, ZINC ION
Authors:Newman, J.A, Aitkenhead, H, Gavard, A, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2019-02-26
Release date:2019-07-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 2019
6QAJ
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BU of 6qaj by Molmil
Structure of the tripartite motif of KAP1/TRIM28
Descriptor: Endolysin,Transcription intermediary factor 1-beta, ZINC ION
Authors:Stoll, G.A, Oda, S, Yu, M, Modis, Y.
Deposit date:2018-12-19
Release date:2019-07-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.
Proc.Natl.Acad.Sci.USA, 116, 2019
6IMQ
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BU of 6imq by Molmil
Crystal structure of PML B1-box multimers
Descriptor: CHLORIDE ION, Protein PML, ZINC ION
Authors:Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G.
Deposit date:2018-10-23
Release date:2019-07-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis.
Nat Commun, 10, 2019
6H3A
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BU of 6h3a by Molmil
Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain.
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION
Authors:Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2018-07-17
Release date:2019-06-26
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (5.505 Å)
Cite:A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 27, 2019
5OLM
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BU of 5olm by Molmil
TRIM21
Descriptor: E3 ubiquitin-protein ligase TRIM21, ZINC ION
Authors:James, L.C.
Deposit date:2017-07-28
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife, 7, 2018
5W9A
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BU of 5w9a by Molmil
The structure of the Trim5alpha Bbox- coiled coil in complex LC3B
Descriptor: Microtubule-associated proteins 1A/1B light chain 3B, Tripartite motif-containing protein 5, ZINC ION
Authors:Keown, J.R, Goldstone, D.C.
Deposit date:2017-06-22
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5 alpha and mammalian autophagy-related ATG8 proteins.
J. Biol. Chem., 293, 2018
5VA4
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BU of 5va4 by Molmil
TRIM-Cyclophilin A B-box 2 and coiled-coil chimera
Descriptor: TRIM5/cyclophilin A V4 fusion protein, ZINC ION
Authors:Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O.W.
Deposit date:2017-03-24
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins.
J. Virol., 92, 2018
5K3Q
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BU of 5k3q by Molmil
Rhesus macaques Trim5alpha Bbox2 domain
Descriptor: NITRATE ION, Tripartite motif-containing protein 5,Tripartite motif-containing protein 5, ZINC ION
Authors:Keown, J.K, Goldstone, D.C.
Deposit date:2016-05-19
Release date:2016-07-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Trim5 alpha Bbox2 domain from rhesus macaques describes a plastic oligomerisation interface.
J.Struct.Biol., 195, 2016
5JPX
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BU of 5jpx by Molmil
Solution structure of the TRIM21 B-box2 (B2)
Descriptor: E3 ubiquitin-protein ligase TRIM21, ZINC ION
Authors:Wallenhammar, A, Anandapadamanaban, M, Sunnerhagen, M.
Deposit date:2016-05-04
Release date:2017-08-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain.
PLoS ONE, 12, 2017
5IEA
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BU of 5iea by Molmil
TRIM5 B-box2 and coiled-coil chimera
Descriptor: Tripartite motif-containing protein 5, Serine--tRNA ligase Chimera, ZINC ION
Authors:Wagner, J.M, Doss, G, Pornillos, O.
Deposit date:2016-02-25
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.258 Å)
Cite:Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5 alpha.
Elife, 5, 2016

 

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