PDB: 19 resultsInfo pagesStatus searchChemie searchBIRD

---

5L73	MAM domain of human neuropilin-1 Descriptor: BICINE, CALCIUM ION, Neuropilin-1, ... Authors: Yelland, T, Djordjevic, S. Deposit date: 2016-06-01 Release date: 2016-10-26 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture. Structure, 24, 2016
8A28	Structure of the astacin zymogen of LAST-MAM from Limulus polyphemus Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ... Authors: Guevara, T, Rodriguez Banqueri, A. Deposit date: 2022-06-02 Release date: 2022-10-19 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Zymogenic latency in an ∼250-million-year-old astacin metallopeptidase. Acta Crystallogr D Struct Biol, 78, 2022
7AQ1	Crystal structure of human mature meprin beta in complex with the specific inhibitor MWT-S-270 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Linnert, M, Parthier, C, Fritz, C. Deposit date: 2020-10-20 Release date: 2021-03-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.413 Å) Cite: Structure and Dynamics of Meprin beta in Complex with a Hydroxamate-Based Inhibitor. Int J Mol Sci, 22, 2021
4GWM	Crystal structure of human promeprin beta Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... Authors: Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. Deposit date: 2012-09-03 Release date: 2012-09-19 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
4GWN	Crystal structure of human mature meprin beta Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. Deposit date: 2012-09-03 Release date: 2012-09-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
5OJ2	Crystal structure of the chicken MDGA1 ectodomain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Elegheert, J, Clayton, A.J, Aricescu, A.R. Deposit date: 2017-07-20 Release date: 2017-08-23 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron, 95, 2017
7UAB	Human pro-meprin alpha (zymogen state) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C. Deposit date: 2022-03-12 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022
7UAE	Human meprin alpha (active state) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C. Deposit date: 2022-03-12 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022
7UAC	Human pro-meprin alpha (zymogen state) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Meprin A subunit alpha, ... Authors: Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C. Deposit date: 2022-03-12 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022
7UAF	Human meprin alpha inhibitory complex with compound 10d (N~3~,N~3~-bis[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-beta-alaninamide) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C. Deposit date: 2022-03-12 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022
8A1F	Human PTPRK N-terminal domains MAM-Ig-FN1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E. Deposit date: 2022-06-01 Release date: 2023-03-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3 Å) Cite: Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
2C9A	Crystal structure of the MAM-Ig module of receptor protein tyrosine phosphatase mu Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, ... Authors: Aricescu, A.R, Hon, W.C, Siebold, C, Lu, W, Van Der Merwe, P.A, Jones, E.Y. Deposit date: 2005-12-09 Release date: 2006-01-19 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular Analysis of Receptor Protein Tyrosine Phosphatase Mu-Mediated Cell Adhesion. Embo J., 25, 2006
2V5Y	Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, SODIUM ION Authors: Aricescu, A.R, Siebold, C, Choudhuri, K, Chang, V.T, Lu, W, Davis, S.J, van der Merwe, P.A, Jones, E.Y. Deposit date: 2007-07-11 Release date: 2007-09-11 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism. Science, 317, 2007
7AUW	Inhibitory complex of human meprin beta with mouse fetuin-B. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fetuin-B, ... Authors: Eckhard, U, Gomis-Ruth, F.X. Deposit date: 2020-11-03 Release date: 2021-04-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The crystal structure of a 250-kDa heterotetrameric particle explains inhibition of sheddase meprin beta by endogenous fetuin-B. Proc.Natl.Acad.Sci.USA, 118, 2021
8H3U	Inhibitor-bound EP, polyA model Descriptor: Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain Authors: Ding, Z.Y, Huang, H.J. Deposit date: 2022-10-09 Release date: 2022-11-23 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
8H3S	Substrate-bound EP, polyA model Descriptor: Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain, Serine protease 1 Authors: Ding, Z.Y, Huang, H.J. Deposit date: 2022-10-09 Release date: 2022-11-23 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
5OJ6	Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1 (NL1(-A-B)) cholinesterase domain. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, Neuroligin-1, ... Authors: Elegheert, J, Clayton, A.J, Aricescu, A.R. Deposit date: 2017-07-20 Release date: 2017-08-23 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron, 95, 2017
7T4S	CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein H, ... Authors: Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. Deposit date: 2021-12-10 Release date: 2022-03-23 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
7UAI	Meprin alpha helix in complex with fetuin-B Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C. Deposit date: 2022-03-13 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022