Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8BO0
DownloadVisualize
BU of 8bo0 by Molmil
Solution structure of Lqq4 toxin from Leiurus quinquestriatus quinquestriatus
Descriptor: Alpha-toxin Lqq4
Authors:Mineev, K.S, Motov, V.V, Vassilevski, A.A, Chernykh, M.A, Kuzmenkov, A.I.
Deposit date:2022-11-14
Release date:2023-09-20
Last modified:2023-10-04
Method:SOLUTION NMR
Cite:A scorpion toxin affecting sodium channels shows double cis-trans isomerism.
Febs Lett., 597, 2023
7XSU
DownloadVisualize
BU of 7xsu by Molmil
Cardiac sodium channel in complex with LqhIII
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-like toxin Lqh3, ...
Authors:Jiang, D, Catterall, W.A.
Deposit date:2022-05-15
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Basis for Nav1.5 Opening Modulated by a Gating Modifier Toxin
To Be Published
7K18
DownloadVisualize
BU of 7k18 by Molmil
Cardiac Sodium channel with toxin bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-like toxin Lqh3, ...
Authors:Jiang, D, Catterall, W.A.
Deposit date:2020-09-07
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin.
Nat Commun, 12, 2021
6VXW
DownloadVisualize
BU of 6vxw by Molmil
NMR solution structure of natural scorpion toxin Cl13
Descriptor: Beta-toxin Cl13
Authors:del Rio Portilla, F, Delepierre, M, Lopez Giraldo, A.E.
Deposit date:2020-02-24
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus.
Toxicon, 184, 2020
6THI
DownloadVisualize
BU of 6thi by Molmil
Solution structure of MeuNaTxalpha-1 toxin from Mesobuthus Eupeus
Descriptor: Sodium channel neurotoxin MeuNaTxalpha-1
Authors:Mineev, K.S, Kuzmenkov, A.I, Khusainov, G.A, Arseniev, A.S, Vassilevski, A.A.
Deposit date:2019-11-20
Release date:2020-12-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of MeuNaTx alpha-1 toxin from scorpion venom highlights the importance of the nest motif.
Proteins, 2021
6NT4
DownloadVisualize
BU of 6nt4 by Molmil
Cryo-EM structure of a human-cockroach hybrid Nav channel bound to alpha-scorpion toxin AaH2.
Descriptor: (7E,21R,24S)-27-amino-24-hydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaheptacos-7-en-21-yl (9Z,12E)-octadeca-9,12-dienoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Clairfeuille, T, Rohou, A, Payandeh, J.
Deposit date:2019-01-28
Release date:2019-02-20
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of alpha-scorpion toxin action on Na v channels.
Science, 363, 2019
5MOU
DownloadVisualize
BU of 5mou by Molmil
NMR spatial structure of scorpion alpha-like toxin BeM9
Descriptor: Alpha-mammal toxin BeM9
Authors:Mineev, K.S, Kuldushev, N.A, Berkut, A.A, Grishin, E.V, Vassilevski, A.A, Arseniev, A.S.
Deposit date:2016-12-14
Release date:2018-01-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Refined structure of BeM9 reveals arginine hand, an overlooked structural motif in scorpion toxins affecting sodium channels.
Proteins, 86, 2018
5CY0
DownloadVisualize
BU of 5cy0 by Molmil
Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography
Descriptor: GLYCEROL, Ts3 Toxin
Authors:Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B.
Deposit date:2015-07-29
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
Angew.Chem.Int.Ed.Engl., 55, 2016
4V1D
DownloadVisualize
BU of 4v1d by Molmil
Ternary complex among two human derived single chain antibody fragments and Cn2 toxin from scorpion Centruroides noxius.
Descriptor: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT LR, HEAVY CHAIN, ...
Authors:Riano-Umbarila, L, Serrano-Posada, H, Rojas-Trejo, S, Rudino-Pinera, E, Becerril, B.
Deposit date:2014-09-25
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Optimal Neutralization of Centruroides Noxius Venom is Understood Through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.
J.Biol.Chem., 291, 2016
4KYP
DownloadVisualize
BU of 4kyp by Molmil
Beta-Scorpion Toxin folded in the periplasm of E.coli
Descriptor: Beta-insect excitatory toxin Bj-xtrIT, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL
Authors:O'Reilly, A.O, Cole, A.R, Lopes, J.L, Lampert, A, Wallace, B.A.
Deposit date:2013-05-29
Release date:2014-02-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chaperone-mediated native folding of a beta-scorpion toxin in the periplasm of Escherichia coli.
Biochim.Biophys.Acta, 1840, 2014
4HHF
DownloadVisualize
BU of 4hhf by Molmil
Crystal Structure of chemically synthesized scorpion alpha-toxin OD1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-toxin OD1
Authors:Wang, C.I.A, Lewis, R.J, Alewood, P.F, Durek, T.
Deposit date:2012-10-09
Release date:2013-04-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
Acs Chem.Biol., 8, 2013
4AEI
DownloadVisualize
BU of 4aei by Molmil
Crystal structure of the AaHII-Fab4C1 complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALPHA-MAMMAL TOXIN AAH2, CHLORIDE ION, ...
Authors:Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P.
Deposit date:2012-01-10
Release date:2012-03-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
J.Biol.Chem., 287, 2012
2YEO
DownloadVisualize
BU of 2yeo by Molmil
A39L mutation of scorpion toxin lqh-alpha-it
Descriptor: 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ...
Authors:Frolow, F, Kahn, R, Gurevitz, M.
Deposit date:2011-03-28
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels
To be Published
2YC1
DownloadVisualize
BU of 2yc1 by Molmil
Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
Descriptor: BETA-MAMMAL TOXIN CN2, GLYCEROL, SINGLE CHAIN ANTIBODY FRAGMENT 9004G
Authors:Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A.
Deposit date:2011-03-10
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment.
J.Biol.Chem., 286, 2011
2YBR
DownloadVisualize
BU of 2ybr by Molmil
Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
Descriptor: BETA-MAMMAL TOXIN CN2, SINGLE CHAIN ANTIBODY FRAGMENT 9004G
Authors:Canul-Tec, J.C, Riano-Umbarila, L, Rudino-Pinera, E, Becerril, B, Possani, L.D, Torres-Larios, A.
Deposit date:2011-03-09
Release date:2011-04-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment
J.Biol.Chem., 286, 2011
2SN3
DownloadVisualize
BU of 2sn3 by Molmil
STRUCTURE OF SCORPION TOXIN VARIANT-3 AT 1.2 ANGSTROMS RESOLUTION
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, SCORPION NEUROTOXIN (VARIANT 3)
Authors:Zhao, B, Carson, M, Ealick, S.E, Bugg, C.E.
Deposit date:1992-02-20
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of scorpion toxin variant-3 at 1.2 A resolution.
J.Mol.Biol., 227, 1992
2LKB
DownloadVisualize
BU of 2lkb by Molmil
Evolutionary diversification of Mesobuthus alpha-scorpion toxins affecting sodium channels
Descriptor: Neurotoxin MeuNaTx-5
Authors:Zhu, S, Peigneur, S, Gao, B, Lu, X, Cao, C, Tytgat, J.
Deposit date:2011-10-09
Release date:2011-11-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Evolutionary diversification of Mesobuthus {alpha}-scorpion toxins affecting sodium channels
Mol.Cell Proteomics, 2011
2LJM
DownloadVisualize
BU of 2ljm by Molmil
Solution Structure of CssII
Descriptor: Beta-mammal toxin Css2
Authors:del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
Deposit date:2011-09-20
Release date:2012-02-15
Method:SOLUTION NMR
Cite:Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
Biochim.Biophys.Acta, 1824, 2012
2LI7
DownloadVisualize
BU of 2li7 by Molmil
Solution Structure of CssII
Descriptor: Beta-mammal toxin Css2
Authors:del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
Deposit date:2011-08-24
Release date:2012-02-15
Method:SOLUTION NMR
Cite:Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels.
Biochim.Biophys.Acta, 1824, 2012
2KJA
DownloadVisualize
BU of 2kja by Molmil
Chemical shift assignments, constraints, and coordinates for CN5 scorpion toxin
Descriptor: Beta-toxin Cn5
Authors:Prochnicka-Chalufour, A, Corzo, G, Garcia, B.I, Possani, L.D, Delepierre, M.
Deposit date:2009-05-26
Release date:2009-10-06
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Biochim.Biophys.Acta, 1794, 2009
2KBK
DownloadVisualize
BU of 2kbk by Molmil
Solution Structure of BmK-M10
Descriptor: Neurotoxin BmK-M10
Authors:Zhu, J, Wu, H.
Deposit date:2008-11-28
Release date:2009-12-22
Last modified:2019-12-11
Method:SOLUTION NMR
Cite:Solution Structure of BmK-M10
To be Published
2KBJ
DownloadVisualize
BU of 2kbj by Molmil
solution structure of BmKalphaTx11 (minor conformation)
Descriptor: Toxin Bmka2
Authors:Zhu, J, Wu, H.
Deposit date:2008-11-28
Release date:2009-12-08
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 391, 2010
2KBH
DownloadVisualize
BU of 2kbh by Molmil
solution structure of BmKalphaTx11 (major conformation)
Descriptor: Toxin Bmka2
Authors:Zhu, J, Wu, H.
Deposit date:2008-11-28
Release date:2009-12-08
Last modified:2019-12-11
Method:SOLUTION NMR
Cite:Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 391, 2010
2I61
DownloadVisualize
BU of 2i61 by Molmil
Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ...
Authors:Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D.
Deposit date:2006-08-27
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity.
J.Mol.Biol., 366, 2007
2E0H
DownloadVisualize
BU of 2e0h by Molmil
Solution Structure of BmKalphaIT01, an alpha-insect toxin from the Venom of the Chinese Scorpion Buthus martensi Karsch
Descriptor: Alpha-neurotoxin TX12
Authors:Tong, X.T, Chen, X, Wu, H.M.
Deposit date:2006-10-08
Release date:2007-10-16
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution Structure of BmKalphaIT01, an alpha-Insect Toxin from the Venom of the Chinese Scorpion Buthus martensii Karsch
Biochemistry, 46, 2007

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon