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6VSU
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BU of 6vsu by Molmil
Arginase from Arabidopsis thaliana in Complex with Ornithine
Descriptor: Arginase 1, mitochondrial, DI(HYDROXYETHYL)ETHER, ...
Authors:Sekula, B.
Deposit date:2020-02-11
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Front Plant Sci, 11, 2020
7OI1
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BU of 7oi1 by Molmil
Crystal structure of Synechocystis sp PCC6803 guanidinium hydrolase
Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ...
Authors:Fleming, J.R, Mayans, O.M.
Deposit date:2021-05-11
Release date:2021-12-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of a Ni 2+ -dependent guanidine hydrolase in bacteria.
Nature, 603, 2022
5CEV
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BU of 5cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX
Descriptor: GUANIDINE, LYSINE, MANGANESE (II) ION, ...
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-16
Release date:1999-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
6DKT
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BU of 6dkt by Molmil
Crystal structure of Arginase from Bacillus subtilis
Descriptor: Arginase, MANGANESE (II) ION
Authors:Lewis, M.C, Hollingsworth, S.A, Holden, J.K, Poulos, T.L.
Deposit date:2018-05-30
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of Arginase from Bacillus subtilis at 2.08 Angstroms resolution
To Be Published
5RLA
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BU of 5rla by Molmil
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Descriptor: ARGINASE, MANGANESE (II) ION
Authors:Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
Deposit date:1997-05-07
Release date:1998-05-13
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
2ZAV
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BU of 2zav by Molmil
Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolution
Descriptor: Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2007-10-11
Release date:2007-10-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster
J.Am.Chem.Soc., 129, 2007
1D3V
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BU of 1d3v by Molmil
CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W.
Deposit date:1999-10-01
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Arginase-boronic acid complex highlights a physiological role in erectile function.
Nat.Struct.Biol., 6, 1999
1CEV
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BU of 1cev by Molmil
ARGINASE FROM BACILLUS CALDOVELOX, NATIVE STRUCTURE AT PH 5.6
Descriptor: MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-12
Release date:1999-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
8E5M
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BU of 8e5m by Molmil
Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6
Descriptor: 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION
Authors:Palte, R.L, Gathiaka, S.
Deposit date:2022-08-22
Release date:2023-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
8E5N
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BU of 8e5n by Molmil
Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 10
Descriptor: 1-{[(3S,4S)-3-(3-fluorophenyl)-4-{[4-(1,3,4-triethyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl}pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION
Authors:Palte, R.L, Gathiaka, S.
Deposit date:2022-08-22
Release date:2023-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.538 Å)
Cite:Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
5HJ9
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BU of 5hj9 by Molmil
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE
Descriptor: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2016-01-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HJA
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BU of 5hja by Molmil
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHDP
Descriptor: (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid, Arginase, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2016-01-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4CEV
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BU of 4cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX
Descriptor: GUANIDINE, L-ornithine, MANGANESE (II) ION, ...
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-15
Release date:1999-04-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
4DZ4
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BU of 4dz4 by Molmil
X-ray crystal structure of a hypothetical Agmatinase from Burkholderia thailandensis
Descriptor: 1,2-ETHANEDIOL, Agmatinase, MANGANESE (II) ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-02-29
Release date:2012-03-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
8AUP
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BU of 8aup by Molmil
Structure of hARG1 with a novel inhibitor.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, ...
Authors:Napiorkowska-Gromadzka, A, Nowak, E, Nowotny, M.
Deposit date:2022-08-25
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Mol.Cancer Ther., 22, 2023
8C0H
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BU of 8c0h by Molmil
Crystal structure of guanidinase from Nitrospira inopinata
Descriptor: NICKEL (II) ION, Putative agmatinase 2, SULFATE ION
Authors:Puehringer, D.
Deposit date:2022-12-16
Release date:2023-12-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Growth of complete ammonia oxidizers on guanidine
To Be Published
8D27
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BU of 8d27 by Molmil
Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum
Descriptor: Arginase
Authors:Chan, A.C, Kolesnikov, M, Murphy, M.E.
Deposit date:2022-05-27
Release date:2022-07-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species.
Biochemistry, 61, 2022
5YNL
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BU of 5ynl by Molmil
Crystal structure of a cold-adapted arginase from psychrophilic yeast, Glaciozyma antarctica
Descriptor: Arginase
Authors:Yusof, N.Y, Quay, D.H.X, Illias, R.M, Firdaus-Raih, M, Abu-Bakar, F.D, Mahadi, N.M, Murad, A.M.A.
Deposit date:2017-10-24
Release date:2018-01-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Crystal structure of a cold-adapted arginase from psychrophilic yeast, Glaciozyma antarctica
To Be Published
5ZEF
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BU of 5zef by Molmil
Crystal structure of Entamoeba histolytica Arginase in complex with L- Norvaline at 2.01 A
Descriptor: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ...
Authors:Malik, A, Dalal, V, Ankri, S, Tomar, S.
Deposit date:2018-02-27
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
5ZEH
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BU of 5zeh by Molmil
Crystal structure of Entamoeba histolytica Arginase in complex with L- Ornithine at 2.35 A
Descriptor: 1,2-ETHANEDIOL, Arginase, L-ornithine, ...
Authors:Malik, A, Dalal, V, Ankri, S, Tomar, S.
Deposit date:2018-02-27
Release date:2019-06-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
5ZEE
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BU of 5zee by Molmil
Crystal structure of Entamoeba histolytica Arginase in complex with N(omega)-hydroxy-L-arginine (NOHA) at 1.74 A
Descriptor: 1,2-ETHANEDIOL, Arginase, MANGANESE (II) ION, ...
Authors:Malik, A, Dalal, V, Ankri, S, Tomar, S.
Deposit date:2018-02-27
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Febs J., 286, 2019
2PHA
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BU of 2pha by Molmil
Crystal structure of native, unliganded human arginase at 1.90 resolution
Descriptor: Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Pique, M.E, Christianson, D.W.
Deposit date:2007-04-10
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
2PLL
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BU of 2pll by Molmil
Crystal structure of perdeuterated human arginase I
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, arginase-1
Authors:Di Costanzo, L, Moulin, M, Haertlein, M, Meilleur, F, Christianson, D.W.
Deposit date:2007-04-19
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Expression, purification, assay, and crystal structure of perdeuterated human arginase I
Arch.Biochem.Biophys., 465, 2007
2PHO
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BU of 2pho by Molmil
Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution
Descriptor: Arginase-1, HYDRAZINECARBOTHIOAMIDE, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2007-04-11
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.
J.Am.Chem.Soc., 129, 2007
2RLA
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BU of 2rla by Molmil
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Descriptor: ARGINASE, MANGANESE (II) ION
Authors:Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
Deposit date:1997-05-07
Release date:1998-05-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997

217705

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