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4ESP
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BU of 4esp by Molmil
Crystal Structure of Peanut Allergen Ara h 5
Descriptor: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Profilin
Authors:Wang, Y, Zhang, Y.Z.
Deposit date:2012-04-23
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal Structure of Peanut ( Arachis hypogaea ) Allergen Ara h 5.
J.Agric.Food Chem., 61, 2013
1AWI
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BU of 1awi by Molmil
HUMAN PLATELET PROFILIN COMPLEXED WITH THE L-PRO10 PEPTIDE
Descriptor: L-PRO10, PROFILIN
Authors:Mahoney, N.M, Almo, S.C.
Deposit date:1997-10-02
Release date:1998-10-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulation.
Nat.Struct.Biol., 4, 1997
4QWO
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BU of 4qwo by Molmil
1.52 Angstrom Crystal Structure of A42R Profilin-like Protein from Monkeypox Virus Zaire-96-I-16
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ...
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Flores, K, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-07-16
Release date:2014-08-06
Last modified:2022-10-12
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structure of the Monkeypox virus profilin-like protein A42R reveals potential functional differences from cellular profilins.
Acta Crystallogr.,Sect.F, 78, 2022
7KYW
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BU of 7kyw by Molmil
Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer
Descriptor: CITRIC ACID, Profilin-1
Authors:O'Malley, A, Kapingidza, A.B, Hyduke, N, Dolamore, C, Chruszcz, M.
Deposit date:2020-12-09
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of timothy grass allergen Phl p 12.0101 reveals an unusual profilin dimer.
Acta Biochim.Pol., 68, 2021
4D60
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BU of 4d60 by Molmil
Structure of a dimeric Plasmodium falciparum profilin mutant
Descriptor: PROFILIN, SULFATE ION
Authors:Bhargav, S.P, Vahokoski, J, Kallio, J.P, Torda, A, Kursula, P, Kursula, I.
Deposit date:2014-11-07
Release date:2015-06-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Two Independently Folding Units of Plasmodium Profilin Suggest Evolution Via Gene Fusion.
Cell.Mol.Life Sci., 72, 2015
5NZC
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BU of 5nzc by Molmil
A disulfide switch determines proteolytic resistance in the birch pollen allergen Bet v 2
Descriptor: Profilin-2
Authors:Soh, W.T, Brandstetter, H.
Deposit date:2017-05-12
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.
Int J Mol Sci, 18, 2017
5NZB
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BU of 5nzb by Molmil
A disulfide switch determines proteolytic resistance in the birch pollen allergen Bet v 2
Descriptor: Profilin-2
Authors:Soh, W.T, Brandstetter, H.
Deposit date:2017-05-12
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.695 Å)
Cite:Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.
Int J Mol Sci, 18, 2017
1ACF
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BU of 1acf by Molmil
ACANTHAMOEBA CASTELLANII PROFILIN IB
Descriptor: PROFILIN I
Authors:Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C.
Deposit date:1994-07-29
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.
Proc.Natl.Acad.Sci.USA, 91, 1994
1A0K
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BU of 1a0k by Molmil
PROFILIN I FROM ARABIDOPSIS THALIANA
Descriptor: PROFILIN
Authors:Shigeta Junior, R, Huddler, D, Lindberg, U, Schutt, C.E.
Deposit date:1997-12-02
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of a major allergen from plants.
Structure, 5, 1997
3NEC
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BU of 3nec by Molmil
Crystal Structure of Toxoplasma gondii Profilin
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Inflammatory profilin, SULFATE ION
Authors:Kucera, K, Modis, Y.
Deposit date:2010-06-08
Release date:2010-09-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11.
J.Mol.Biol., 403, 2010
3NUL
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BU of 3nul by Molmil
Profilin I from Arabidopsis thaliana
Descriptor: GLYCEROL, PROFILIN I, SULFATE ION
Authors:Thorn, K, Christensen, H.E.M, Shigeta, R, Huddler, D, Chua, N.-H, Shalaby, L, Lindberg, U, Schutt, C.E.
Deposit date:1996-11-27
Release date:1997-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of a major allergen from plants.
Structure, 5, 1997
1K0K
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BU of 1k0k by Molmil
Yeast Profilin, Cubic Crystal Form
Descriptor: GLYCEROL, PROFILIN
Authors:Vorobiev, S, Fedorov, A.A, Almo, S.C.
Deposit date:2001-09-19
Release date:2001-10-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A Comparative Structural Analysis of Profilins
To be Published
7SBG
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BU of 7sbg by Molmil
Murine Fab/IgE in complex with profilin from Hevea brasieliensis (Hev b 8)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab/IgE Heavy chain, Fab/IgE Light chain, ...
Authors:Rodriguez-Romero, A, Garcia-Ramirez, B.
Deposit date:2021-09-24
Release date:2022-08-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:A native IgE in complex with profilin provides insights into allergen recognition and cross-reactivity.
Commun Biol, 5, 2022
7SBD
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BU of 7sbd by Molmil
Murine Fab/IgE in complex with profilin from Hevea brasieliensis (Hev b 8)
Descriptor: Fab/IgE Heavy chain, Fab/IgE Light chain, Profilin-2, ...
Authors:Rodriguez-Romero, A, Garcia-Ramirez, B.
Deposit date:2021-09-24
Release date:2022-08-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:A native IgE in complex with profilin provides insights into allergen recognition and cross-reactivity.
Commun Biol, 5, 2022
7PBH
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BU of 7pbh by Molmil
Structural characterization of Thorarchaeota profilin indicates a eukaryotic-like fold but with an extended N-terminus
Descriptor: Profilin
Authors:Celestine, C.
Deposit date:2021-08-02
Release date:2022-08-10
Last modified:2024-02-21
Method:SOLUTION NMR
Cite:Structural Characterization of a Thorarchaeota Profilin Indicates Eukaryotic-Like Features but with an Extended N-Terminus.
Adv Biol (Weinh), 6, 2022
2JKF
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BU of 2jkf by Molmil
Plasmodium falciparum profilin
Descriptor: PROFILIN
Authors:Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum
Structure, 16, 2008
2JKG
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BU of 2jkg by Molmil
Plasmodium falciparum profilin
Descriptor: MAGNESIUM ION, OCTAPROLINE PEPTIDE, PROFILIN
Authors:Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H.
Deposit date:2008-08-28
Release date:2008-09-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum.
Structure, 16, 2008
1YPR
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BU of 1ypr by Molmil
SACCHAROMYCES CEREVISIAE (YEAST) PROFILIN
Descriptor: PROFILIN
Authors:Eads, J.C, Mahoney, N.M, Almo, S.C.
Deposit date:1997-06-26
Release date:1997-12-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure determination and characterization of Saccharomyces cerevisiae profilin
Biochemistry, 37, 1998
4X1L
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BU of 4x1l by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Descriptor: PHOSPHATE ION, Profilin-1
Authors:Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X25
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BU of 4x25 by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Descriptor: Profilin-1
Authors:Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
Deposit date:2014-11-25
Release date:2015-06-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4X1M
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BU of 4x1m by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Descriptor: Profilin-1
Authors:Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
Deposit date:2014-11-24
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
2VK3
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BU of 2vk3 by Molmil
Crystal structure of rat profilin 2a
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, PROFILIN-2, ...
Authors:Haikarainen, T, Kursula, P.
Deposit date:2007-12-17
Release date:2009-02-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure, Modifications and Ligand-Binding Properties of Rat Profilin 2A.
Acta Crystallogr.,Sect.D, 65, 2009
2V8C
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BU of 2v8c by Molmil
Mouse Profilin IIa in complex with the proline-rich domain of VASP
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
Authors:Kursula, P, Downer, J, Witke, W, Wilmanns, M.
Deposit date:2007-08-06
Release date:2007-12-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2V8F
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BU of 2v8f by Molmil
Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
Authors:Kursula, P, Kursula, I, Downer, J, Witke, W, Wilmanns, M.
Deposit date:2007-08-07
Release date:2007-12-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2ACG
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BU of 2acg by Molmil
ACANTHAMOEBA CASTELLANII PROFILIN II
Descriptor: PROFILIN II
Authors:Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C.
Deposit date:1994-08-30
Release date:1994-11-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.
Proc.Natl.Acad.Sci.USA, 91, 1994

 

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