2ZW3
 
 | | Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution | | Descriptor: | Gap junction beta-2 protein | | Authors: | Maeda, S, Nakagawa, S, Suga, M, Yamashita, E, Oshima, A, Fujiyoshi, Y, Tsukihara, T. | | Deposit date: | 2008-12-01 | | Release date: | 2009-04-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of the connexin 26 gap junction channel at 3.5 A resolution
Nature, 458, 2009
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3IZ1
 | | C-alpha model fitted into the EM structure of Cx26M34A | | Descriptor: | Gap junction beta-2 protein | | Authors: | Oshima, A, Tani, K, Toloue, M.M, Hiroaki, Y, Smock, A, Inukai, S, Cone, A, Nicholson, B.J, Sosinsky, G.E, Fujiyoshi, Y. | | Deposit date: | 2010-08-19 | | Release date: | 2010-11-03 | | Last modified: | 2024-02-21 | | Method: | ELECTRON CRYSTALLOGRAPHY (6 Å) | | Cite: | Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.
J.Mol.Biol., 405, 2011
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3IZ2
 | | C-alpha model fitted into the EM structure of Cx26M34Adel2-7 | | Descriptor: | Gap junction beta-2 protein | | Authors: | Oshima, A, Tani, K, Toloue, M.M, Hiroaki, Y, Smock, A, Inukai, S, Cone, A, Nicholson, B.J, Sosinsky, G.E, Fujiyoshi, Y. | | Deposit date: | 2010-08-19 | | Release date: | 2010-11-03 | | Last modified: | 2024-02-21 | | Method: | ELECTRON CRYSTALLOGRAPHY (10 Å) | | Cite: | Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.
J.Mol.Biol., 405, 2011
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5ER7
 | | Connexin-26 Bound to Calcium | | Descriptor: | CALCIUM ION, Gap junction beta-2 protein | | Authors: | Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J. | | Deposit date: | 2015-11-13 | | Release date: | 2016-01-27 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (3.286 Å) | | Cite: | An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels.
Nat Commun, 7, 2016
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5ERA
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6L3T
 | | Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium | | Descriptor: | Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | | Deposit date: | 2019-10-15 | | Release date: | 2020-09-09 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (2.34 Å) | | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
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6L3U
 | | Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium | | Descriptor: | CALCIUM ION, Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | | Deposit date: | 2019-10-15 | | Release date: | 2020-09-09 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
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6L3V
 | | The R15G mutant of human Cx31.3/GJC3 connexin hemichannel | | Descriptor: | Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol | | Authors: | Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S. | | Deposit date: | 2019-10-15 | | Release date: | 2020-09-09 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
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6MHQ
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6MHY
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6UVR
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6UVS
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6UVT
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7F92
 | | Structure of connexin43/Cx43/GJA1 gap junction intercellular channel in LMNG/CHS detergents at pH ~8.0 | | Descriptor: | Gap junction alpha-1 protein, TETRADECANE | | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | | Deposit date: | 2021-07-03 | | Release date: | 2022-07-06 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
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7F93
 | | Structure of connexin43/Cx43/GJA1 gap junction intercellular channel in nanodiscs with soybean lipids at pH ~8.0 | | Descriptor: | Gap junction alpha-1 protein, TETRADECANE | | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | | Deposit date: | 2021-07-03 | | Release date: | 2022-07-06 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
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7F94
 | | Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel with two conformationally different hemichannels | | Descriptor: | A C-terminal deletion mutant of gap junction alpha-1 protein (Cx43-M257) | | Authors: | Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S. | | Deposit date: | 2021-07-03 | | Release date: | 2022-07-06 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
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7JJP
 | | Sheep Connexin-50 at 1.9 angstroms resolution by CryoEM | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-07-27 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (1.94 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JKC
 | | Sheep Connexin-46 at 1.9 angstroms resolution by CryoEM | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-07-28 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (1.9 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JLW
 | | Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 1 | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-07-30 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JM9
 | | Sheep Connexin-50 at 2.5 angstroms reoslution, Lipid Class 2 | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-07-31 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JMC
 | | Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 3 | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-07-31 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JMD
 | | Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 1 | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-07-31 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JN0
 | | Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 2 | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.A, Myers, J.A, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-08-03 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7JN1
 | | Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3 | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein | | Authors: | Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L. | | Deposit date: | 2020-08-03 | | Release date: | 2020-09-09 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
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7QEO
 | | human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class C | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | | Deposit date: | 2021-12-03 | | Release date: | 2022-06-22 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26.
Structure, 30, 2022
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