8KDX
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7JT9
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6NMW
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6IPY
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6IPZ
| Fyn SH3 domain R96W mutant, crystallized with 18-crown-6 | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn | Authors: | Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F. | Deposit date: | 2018-11-05 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.576 Å) | Cite: | Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
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5UL6
| The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions | Descriptor: | Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus | Authors: | Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. | Deposit date: | 2017-01-24 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus. ACS Chem. Biol., 12, 2017
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5VEI
| Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 | Descriptor: | Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION | Authors: | Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2017-04-04 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 To be Published
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4Y92
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6RO9
| Human spectrin SH3 domain D48G, E7V, K60V | Descriptor: | Spectrin alpha, non-erythrocytic 1 | Authors: | Reverter, D, Navarro, S, Ventura, S. | Deposit date: | 2019-05-10 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.814 Å) | Cite: | Human spectrin SH3 domain D48G, E7V, K60V To Be Published
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6EDF
| Fragment of a tyrosine-protein kinase | Descriptor: | FYN, GLYCEROL, UNKNOWN ATOM OR ION | Authors: | Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2018-08-09 | Release date: | 2018-08-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Fragment of a tyrosine-protein kinase To be Published
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6SCW
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6SDF
| N-terminal SH3 domain of Grb2 protein | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2 | Authors: | Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B. | Deposit date: | 2019-07-26 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the SH3 domain of growth factor receptor-bound protein 2. Acta Crystallogr.,Sect.F, 76, 2020
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4ZNX
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8WFF
| The Crystal Structure of LYN from Biortus. | Descriptor: | CHLORIDE ION, CITRATE ANION, Tyrosine-protein kinase Lyn | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y. | Deposit date: | 2023-09-19 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The Crystal Structure of LYN from Biortus. To Be Published
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5L23
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7NES
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7NER
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7NET
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7NZC
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7Y4N
| Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos | Descriptor: | Growth factor receptor-bound protein 2 | Authors: | Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y. | Deposit date: | 2022-06-15 | Release date: | 2022-08-31 | Method: | SOLUTION NMR | Cite: | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos. Biochem.Biophys.Res.Commun., 625, 2022
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7YXW
| Structure of the p22phox A200G mutant in complex with p47phox peptide | Descriptor: | Cytochrome b-245 light chain, Neutrophil cytosol factor 1 | Authors: | Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z. | Deposit date: | 2022-02-16 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics Acs Med.Chem.Lett., 13, 2022
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5NP3
| Abl2 SH3 | Descriptor: | Abelson tyrosine-protein kinase 2 | Authors: | Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. | Deposit date: | 2017-04-13 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
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5NP5
| Abl2 SH3 pTyr116/161 | Descriptor: | Abelson tyrosine-protein kinase 2, SULFATE ION | Authors: | Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. | Deposit date: | 2017-04-13 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
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6XVM
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4EIK
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