PDB: 13 resultsInfo pagesStatus searchChemie searchBIRD

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6AXJ	Crystal structure of the Yaf9 YEATS domain bound to H3K27ac Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ... Authors: Klein, B.J, Kutateladze, T.G. Deposit date: 2017-09-06 Release date: 2017-11-22 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (2.379 Å) Cite: Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain. Nucleic Acids Res., 46, 2018
5J9S	ENL YEATS in complex with histone H3 acetylation at K27 Descriptor: H3K27ac peptide from Histone H3.1, Protein ENL, SULFATE ION Authors: Li, Y, Li, H. Deposit date: 2016-04-11 Release date: 2017-03-08 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.702 Å) Cite: ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia Nature, 543, 2017
5XNV	Crystal structure of YEATS2 YEATS bound to H3K27ac peptide Descriptor: ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... Authors: Li, H.T, Guan, H.P, Zhao, D. Deposit date: 2017-05-24 Release date: 2017-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.696 Å) Cite: YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer. Nat Commun, 8, 2017
5XTZ	Crystal structure of GAS41 YEATS bound to H3K27ac peptide Descriptor: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4 Authors: Li, H.T, Zhao, D. Deposit date: 2017-06-21 Release date: 2018-06-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.105 Å) Cite: Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity. Cell Discov, 4, 2018
7X8G	Crystal structure of ENL T1(H116P) mutant YEATS domain in complex with histone H3 acetylation at K27 Descriptor: H3K27ac(24-27) peptide, Protein ENL Authors: Li, Y, Peng, B, Li, H. Deposit date: 2022-03-12 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7X8B	Crystal structure of ENL T1 mutant YEATS domain in complex with histone H3 acetylation at K27 Descriptor: H3K27ac(24-27) peptide, Protein ENL Authors: Li, Y, Peng, B, Li, H. Deposit date: 2022-03-11 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
8IIZ	Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide Descriptor: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ... Authors: Kikuchi, M, Umehara, T. Deposit date: 2023-02-24 Release date: 2023-11-01 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
7E7C	Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27 Descriptor: 1,2-ETHANEDIOL, Histone H3K27ac(24-27) peptide, IODIDE ION, ... Authors: Li, Y, Li, H. Deposit date: 2021-02-25 Release date: 2022-04-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27 To Be Published
7X8F	Crystal structure of ENL T4 mutant YEATS domain in complex with histone H3 acetylation at K27 Descriptor: CHLORIDE ION, H3K27ac(24-27) peptide, Protein ENL Authors: Li, Y, Peng, B, Li, H. Deposit date: 2022-03-12 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7X88	Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27 Descriptor: CITRIC ACID, Histone H3K27ac(24-27) peptide, Protein ENL Authors: Li, Y.Y, Li, H.T. Deposit date: 2022-03-11 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
6KN5	Crystal structure of AFF4 C-terminal domain Descriptor: AF4/FMR2 family member 4 Authors: Chen, L.J, Yang, W.S, Xu, R.M. Deposit date: 2019-08-03 Release date: 2020-07-08 Last modified: 2022-03-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol, 3, 2020
5YE4	Crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment Descriptor: 1A9D7 L chain, 1A9D7 VH CH1 chain, ZINC ION, ... Authors: Matsuda, T, Ito, T, Wakamori, M, Umehara, T. Deposit date: 2017-09-15 Release date: 2018-08-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.799 Å) Cite: JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13, 2018
5YE3	Crystal structure of the complex of di-acetylated histone H4 and 2A7D9 Fab fragment Descriptor: 2A7D9 L chain, 2A7D9 VH CH1 chain, di-acetylated histone H4 Authors: Matsuda, T, Ito, T, Wakamori, M, Umehara, T. Deposit date: 2017-09-15 Release date: 2018-08-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Epigenetics, 13, 2018