6IH6

Phosphite Dehydrogenase mutant I151R/P176R/M207A from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0005829	cellular_component	cytosol
A	0008465	molecular_function	glycerate dehydrogenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0016618	molecular_function	hydroxypyruvate reductase activity
A	0030267	molecular_function	glyoxylate reductase (NADPH) activity
A	0051287	molecular_function	NAD binding
B	0005829	cellular_component	cytosol
B	0008465	molecular_function	glycerate dehydrogenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0016618	molecular_function	hydroxypyruvate reductase activity
B	0030267	molecular_function	glyoxylate reductase (NADPH) activity
B	0051287	molecular_function	NAD binding
C	0005829	cellular_component	cytosol
C	0008465	molecular_function	glycerate dehydrogenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0016618	molecular_function	hydroxypyruvate reductase activity
C	0030267	molecular_function	glyoxylate reductase (NADPH) activity
C	0051287	molecular_function	NAD binding
D	0005829	cellular_component	cytosol
D	0008465	molecular_function	glycerate dehydrogenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0016618	molecular_function	hydroxypyruvate reductase activity
D	0030267	molecular_function	glyoxylate reductase (NADPH) activity
D	0051287	molecular_function	NAD binding

PDBデータベースに由来する情報

site_id	AC1
残基数	15
詳細	binding site for residue A7R A 400

鎖名	残基
A	THR104
A	THR214
A	ALA235
A	CYS236
A	ARG237
A	ASP261
A	GLY295
A	ARG151
A	GLY154
A	ALA155
A	VAL156
A	ASP175
A	ALA207
A	VAL208
A	PRO209

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site_id	AC2
残基数	18
詳細	binding site for residue A7R B 400

鎖名	残基
B	THR104
B	ARG151
B	GLY154
B	ALA155
B	VAL156
B	ASP175
B	ARG176
B	ALA207
B	VAL208
B	PRO209
B	GLU213
B	THR214
B	ALA235
B	CYS236
B	ARG237
B	ASP261
B	HIS293
B	GLY295

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site_id	AC3
残基数	8
詳細	binding site for Di-peptide PRO C 209 and ARG C 237

鎖名	残基
C	VAL208
C	MET210
C	ASN234
C	CYS236
C	GLY238
C	SER239
C	VAL240
C	VAL262

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UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00671
残基数	17
詳細	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKtGsYLINaCRGsVVD

鎖名	残基	詳細
A	MET226-ASP242

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